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1,505 results

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Page 1
The Cortisol Awakening Response: Regulation and Functional Significance.
Stalder T, Oster H, Abelson JL, Huthsteiner K, Klucken T, Clow A. Stalder T, et al. Endocr Rev. 2025 Jan 10;46(1):43-59. doi: 10.1210/endrev/bnae024. Endocr Rev. 2025. PMID: 39177247 Free article. Review.
In healthy individuals, the majority of cortisol secretion occurs within several hours surrounding morning awakening. A highly studied component of this secretory period is the cortisol awakening response (CAR), the rapid increase in cortisol …
In healthy individuals, the majority of cortisol secretion occurs within several hours surrounding morning awakening. A highly …
Stress, the cortisol awakening response and cognitive function.
Law R, Clow A. Law R, et al. Int Rev Neurobiol. 2020;150:187-217. doi: 10.1016/bs.irn.2020.01.001. Epub 2020 Mar 11. Int Rev Neurobiol. 2020. PMID: 32204832 Review.
There is evidence that stress-induced disruption of the circadian rhythm of cortisol secretion, has negative consequences for brain health. The cortisol awakening response (CAR) is the most prominent and dynamic aspect of this rhythm. ...Despite this, …
There is evidence that stress-induced disruption of the circadian rhythm of cortisol secretion, has negative consequences for brain h …
The cortisol awakening response--applications and implications for sleep medicine.
Elder GJ, Wetherell MA, Barclay NL, Ellis JG. Elder GJ, et al. Sleep Med Rev. 2014 Jun;18(3):215-24. doi: 10.1016/j.smrv.2013.05.001. Epub 2013 Jul 5. Sleep Med Rev. 2014. PMID: 23835138 Review.
The stress hormone cortisol is the end product of the hypothalamic-pituitary-adrenal (HPA) axis, and the cortisol awakening response (CAR) refers to the rapid rise in cortisol levels observed immediately following awakening. During the CA …
The stress hormone cortisol is the end product of the hypothalamic-pituitary-adrenal (HPA) axis, and the cortisol awakening …
The cortisol awakening response in context.
Clow A, Hucklebridge F, Thorn L. Clow A, et al. Int Rev Neurobiol. 2010;93:153-75. doi: 10.1016/S0074-7742(10)93007-9. Int Rev Neurobiol. 2010. PMID: 20970005 Review.
The cortisol awakening response (CAR) is a crucial point of reference within the healthy cortisol circadian rhythm, with cortisol secretion typically peaking between 30 and 45 min post awakening. This chapter reviews the history of invest …
The cortisol awakening response (CAR) is a crucial point of reference within the healthy cortisol circadian rhyt …
The cortisol awakening response: more than a measure of HPA axis function.
Clow A, Hucklebridge F, Stalder T, Evans P, Thorn L. Clow A, et al. Neurosci Biobehav Rev. 2010 Sep;35(1):97-103. doi: 10.1016/j.neubiorev.2009.12.011. Epub 2009 Dec 22. Neurosci Biobehav Rev. 2010. PMID: 20026350 Review.
In most healthy people morning awakening is associated with a burst of cortisol secretion: the cortisol awakening response (CAR). ...A role for the hippocampus in this pre-awakening regulation of cortisol secretion is considered. A …
In most healthy people morning awakening is associated with a burst of cortisol secretion: the cortisol awakening …
Cortisol awakening response in patients with psychosis: Systematic review and meta-analysis.
Berger M, Kraeuter AK, Romanik D, Malouf P, Amminger GP, Sarnyai Z. Berger M, et al. Neurosci Biobehav Rev. 2016 Sep;68:157-166. doi: 10.1016/j.neubiorev.2016.05.027. Epub 2016 May 24. Neurosci Biobehav Rev. 2016. PMID: 27229759
The cortisol awakening response (CAR), defined as the increase in cortisol release in response to waking up, shows associations with social and environmental risk factors of schizophrenia and has been studied as a potential biomarker in schizoph …
The cortisol awakening response (CAR), defined as the increase in cortisol release in response to waking …
The cortisol awakening response (CAR): facts and future directions.
Fries E, Dettenborn L, Kirschbaum C. Fries E, et al. Int J Psychophysiol. 2009 Apr;72(1):67-73. doi: 10.1016/j.ijpsycho.2008.03.014. Epub 2008 Sep 30. Int J Psychophysiol. 2009. PMID: 18854200 Review.
In humans, the secretion of cortisol from the adrenal glands follows a diurnal cycle with a profound increase after awakening. This increase after awakening, a phenomenon termed the cortisol awakening response (CAR), appears to be a disti …
In humans, the secretion of cortisol from the adrenal glands follows a diurnal cycle with a profound increase after awakening. …
The cortisol awakening response and major depression: examining the evidence.
Dedovic K, Ngiam J. Dedovic K, et al. Neuropsychiatr Dis Treat. 2015 May 14;11:1181-9. doi: 10.2147/NDT.S62289. eCollection 2015. Neuropsychiatr Dis Treat. 2015. PMID: 25999722 Free PMC article. Review.
There are many ways that the dysregulation of the HPA axis can be assessed: by sampling diurnal basal secretion and/or in response to a stress task, pharmacological challenge, and awakening. Here, we focus on the association between cortisol awakening …
There are many ways that the dysregulation of the HPA axis can be assessed: by sampling diurnal basal secretion and/or in response to …
Awakening not associated with an increased rate of cortisol secretion.
Klaas S, Upton TJ, Zavala E, Lawton M, Bensing S, Berinder K, Botusan I, Grytaas M, Methlie P, Øksnes M, Russell G, Vassiliadi DA, Lightman SL. Klaas S, et al. Proc Biol Sci. 2025 Jan;292(2038):20241844. doi: 10.1098/rspb.2024.1844. Epub 2025 Jan 15. Proc Biol Sci. 2025. PMID: 39809311 Free PMC article.
The endogenous circadian peak of cortisol occurs in the morning, and increases in cortisol observed post-awakening have been named the cortisol awakening response (CAR) based on the belief that the act of waking up stimulates cortisol …
The endogenous circadian peak of cortisol occurs in the morning, and increases in cortisol observed post-awakening have …
Cortisol awakening response in children and adolescents with autism spectrum disorder: a systematic review and meta-analysis.
Hadwin JA, Lee E, Kumsta R, Cortese S, Kovshoff H. Hadwin JA, et al. Evid Based Ment Health. 2019 Aug;22(3):118-124. doi: 10.1136/ebmental-2019-300098. Epub 2019 Jun 28. Evid Based Ment Health. 2019. PMID: 31253603 Free PMC article.
BACKGROUND: The cortisol awakening response (CAR) is characterised by an increase in cortisol in the 30 to 60 min after waking. ...In terms of NOS items, no study specified Representativeness of the cases and Non-response rate. DISCUSSION AND CL …
BACKGROUND: The cortisol awakening response (CAR) is characterised by an increase in cortisol in the 30 to 60 mi …
1,505 results