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18,425 results

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Page 1
A countermeasure development pipeline.
MacRae CA, Boss G, Brenner M, Gerszten RE, Mahon S, Peterson RT. MacRae CA, et al. Ann N Y Acad Sci. 2016 Aug;1378(1):58-67. doi: 10.1111/nyas.13224. Ann N Y Acad Sci. 2016. PMID: 27737495 Free PMC article. Review.
We have developed an integrated pipeline for countermeasure discovery that, under the auspices of the National Institutes of Health Countermeasures Against Chemical Threats network, is one of the few efforts within academia that by design spans the spectrum from dis …
We have developed an integrated pipeline for countermeasure discovery that, under the auspices of the National Institutes of Health …
Development of radiation countermeasure agents for acute radiation syndromes.
Guan B, Li D, Meng A. Guan B, et al. Animal Model Exp Med. 2023 Aug;6(4):329-336. doi: 10.1002/ame2.12339. Epub 2023 Aug 29. Animal Model Exp Med. 2023. PMID: 37642199 Free PMC article. Review.
Therefore, serious security issues have emerged globally, and there has been an increase in the number of studies focusing on radiological prevention and medical countermeasures. Radioprotective drugs are particularly important components of emergency medical preparedness …
Therefore, serious security issues have emerged globally, and there has been an increase in the number of studies focusing on radiological p …
Considerations for carcinogenesis countermeasure development using mouse models.
Nakamura JL. Nakamura JL. Life Sci Space Res (Amst). 2022 Nov;35:158-162. doi: 10.1016/j.lssr.2022.08.005. Epub 2022 Aug 12. Life Sci Space Res (Amst). 2022. PMID: 36336361 Free article. Review.
Thus, developing the countermeasures to address potential effects of ionizing radiation exposure will require understanding biological underpinnings to design countermeasures effectively in conjunction with highly robust modeling approaches to test and examine in vi …
Thus, developing the countermeasures to address potential effects of ionizing radiation exposure will require understanding biologica …
Innovative approaches to COVID-19 medical countermeasure development.
Harris GH, Adalja AA. Harris GH, et al. J Antimicrob Chemother. 2023 Nov 23;78(Suppl 2):ii18-ii24. doi: 10.1093/jac/dkad312. J Antimicrob Chemother. 2023. PMID: 37995353 Free PMC article. Review.
OBJECTIVES: To provide a brief overview of the advances in preventative and therapeutic medical countermeasure development for COVID-19. METHODS: A narrative review of relevant major medical countermeasure trials was conducted using the date range February 2020-Dece …
OBJECTIVES: To provide a brief overview of the advances in preventative and therapeutic medical countermeasure development for COVID- …
Radiation countermeasure agents: an update (2011-2014).
Singh VK, Newman VL, Romaine PL, Wise SY, Seed TM. Singh VK, et al. Expert Opin Ther Pat. 2014 Nov;24(11):1229-55. doi: 10.1517/13543776.2014.964684. Epub 2014 Oct 14. Expert Opin Ther Pat. 2014. PMID: 25315070 Free PMC article. Review.
AREA COVERED: This article reviews relevant publications and patents for recent developments and progress for potential ARS treatments in the area of radiation countermeasures. Emphasis is placed on the advanced development of existing agents since 2011 and new agents iden …
AREA COVERED: This article reviews relevant publications and patents for recent developments and progress for potential ARS treatments in th …
Stimulant Use as a Fatigue Countermeasure in Aviation.
Ehlert AM, Wilson PB. Ehlert AM, et al. Aerosp Med Hum Perform. 2021 Mar 1;92(3):190-200. doi: 10.3357/AMHP.5716.2021. Aerosp Med Hum Perform. 2021. PMID: 33754977 Review.
The identification of efficacious fatigue countermeasures is crucial for sustaining flight performance during fatigue-inducing operations. ...Stimulant use as a fatigue countermeasure in aviation. Aerosp Med Hum Perform. 2021; 92(3):190200....
The identification of efficacious fatigue countermeasures is crucial for sustaining flight performance during fatigue-inducing operat …
Denosumab as a Pharmacological Countermeasure Against Osteopenia in Long Duration Spaceflight.
Rengel A, Tran V, Toh LS. Rengel A, et al. Aerosp Med Hum Perform. 2023 May 1;94(5):389-395. doi: 10.3357/AMHP.6053.2023. Aerosp Med Hum Perform. 2023. PMID: 37069761 Review.
INTRODUCTION: Prolonged exposure to microgravity is associated with a significant reduction in bone density, exposing astronauts to renal calculi in flight and osteoporotic fractures on return to Earth. While physical countermeasures and bisphosphonates may reduce deminera …
INTRODUCTION: Prolonged exposure to microgravity is associated with a significant reduction in bone density, exposing astronauts to renal ca …
Motion Sickness: Current Knowledge and Recent Advance.
Zhang LL, Wang JQ, Qi RR, Pan LL, Li M, Cai YL. Zhang LL, et al. CNS Neurosci Ther. 2016 Jan;22(1):15-24. doi: 10.1111/cns.12468. Epub 2015 Oct 9. CNS Neurosci Ther. 2016. PMID: 26452639 Free PMC article. Review.
This review summarizes the current knowledge about pathogenesis and pathophysiology, prediction, evaluation, and countermeasures of MS. The sensory conflict hypothesis is the most widely accepted theory for MS. ...Repeated real motion exposure and combined visual-vestibula …
This review summarizes the current knowledge about pathogenesis and pathophysiology, prediction, evaluation, and countermeasures of M …
Physiological effects of weightlessness: countermeasure system development for a long-term Chinese manned spaceflight.
Wang L, Li Z, Tan C, Liu S, Zhang J, He S, Zou P, Liu W, Li Y. Wang L, et al. Front Med. 2019 Apr;13(2):202-212. doi: 10.1007/s11684-017-0587-7. Epub 2018 Apr 25. Front Med. 2019. PMID: 29693211 Review.
As a national space laboratory, it will offer unique opportunities for studying the physiological effects of weightlessness and the efficacy of the countermeasures against such effects. In this paper, we described the development of countermeasure systems in the Chi …
As a national space laboratory, it will offer unique opportunities for studying the physiological effects of weightlessness and the efficacy …
An Overview of Radiation Countermeasure Development in Radiation Research from 1954 to 2024.
Kiang JG, Cannon G, Singh VK. Kiang JG, et al. Radiat Res. 2024 Aug 1;202(2):420-431. doi: 10.1667/RADE-24-00036.1. Radiat Res. 2024. PMID: 38964743 Free PMC article. Review.
The identification of these mechanisms suggests molecules and signaling pathways that can be targeted to develop radiation medical countermeasures. Thus far, the United States Food and Drug Administration (U.S. FDA) has approved seven countermeasures to mitigate hem …
The identification of these mechanisms suggests molecules and signaling pathways that can be targeted to develop radiation medical counte …
18,425 results
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