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184 results

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Identification by whole genome sequencing of genes associated with delayed postoperative hemorrhage in Scottish deerhounds.

Court MH, Kiser JN, Neibergs HL, Zhu Z, Dillberger JE. Court MH, et al. J Vet Intern Med. 2023 Mar;37(2):510-517. doi: 10.1111/jvim.16643. Epub 2023 Feb 13. J Vet Intern Med. 2023. PMID: 36780177 Free PMC article.

Bisphenol-A glucuronidation in human liver and breast: identification of UDP-glucuronosyltransferases (UGTs) and influence of genetic polymorphisms.

Street CM, Zhu Z, Finel M, Court MH. Street CM, et al. Among authors: court mh. Xenobiotica. 2017 Jan;47(1):1-10. doi: 10.3109/00498254.2016.1156784. Epub 2016 Mar 21. Xenobiotica. 2017. PMID: 26999266 Free PMC article.

Race, Gender, and Genetic Polymorphism Contribute to Variability in Acetaminophen Pharmacokinetics, Metabolism, and Protein-Adduct Concentrations in Healthy African-American and European-American Volunteers.

Court MH, Zhu Z, Masse G, Duan SX, James LP, Harmatz JS, Greenblatt DJ. Court MH, et al. J Pharmacol Exp Ther. 2017 Sep;362(3):431-440. doi: 10.1124/jpet.117.242107. Epub 2017 Jun 29. J Pharmacol Exp Ther. 2017. PMID: 28663312 Free PMC article.

Pharmacokinetics of Mycophenolic Acid after Intravenous Administration of Mycophenolate Mofetil to Healthy Cats.

Slovak JE, Rivera SM, Hwang JK, Court MH, Villarino NF. Slovak JE, et al. Among authors: court mh. J Vet Intern Med. 2017 Nov;31(6):1827-1832. doi: 10.1111/jvim.14827. Epub 2017 Sep 11. J Vet Intern Med. 2017. PMID: 28892209 Free PMC article.

Absolute Quantitation of Drug-Metabolizing Cytochrome P450 Enzymes and Accessory Proteins in Dog Liver Microsomes Using Label-Free Standard-Free Analysis Reveals Interbreed Variability.

Martinez SE, Shi J, Zhu HJ, Perez Jimenez TE, Zhu Z, Court MH. Martinez SE, et al. Among authors: court mh. Drug Metab Dispos. 2019 Nov;47(11):1314-1324. doi: 10.1124/dmd.119.088070. Epub 2019 Aug 19. Drug Metab Dispos. 2019. PMID: 31427433 Free PMC article.

Canine Albumin Polymorphisms and Their Impact on Drug Plasma Protein Binding.

Costa AP, Court MH, Burke NS, Zhu Z, Mealey KL, Villarino NF. Costa AP, et al. Among authors: court mh. Drug Metab Dispos. 2019 Oct;47(10):1024-1031. doi: 10.1124/dmd.119.087304. Epub 2019 Sep 3. Drug Metab Dispos. 2019. PMID: 31481400 Free PMC article.

Pharmacogenomics of poor drug metabolism in Greyhounds: Cytochrome P450 (CYP) 2B11 genetic variation, breed distribution, and functional characterization.

Martinez SE, Andresen MC, Zhu Z, Papageorgiou I, Court MH. Martinez SE, et al. Among authors: court mh. Sci Rep. 2020 Jan 9;10(1):69. doi: 10.1038/s41598-019-56660-z. Sci Rep. 2020. PMID: 31919457 Free PMC article.

Association of cytochrome P450 2D15 (CYP2D15) nonsynonymous polymorphisms and exon 3 deleted RNA splice variant with CYP2D15 protein content and enzyme function in dog liver microsomes.

Jimenez TP, Zhu Z, Court MH. Jimenez TP, et al. Among authors: court mh. J Vet Pharmacol Ther. 2023 Mar;46(2):77-90. doi: 10.1111/jvp.13113. Epub 2023 Jan 23. J Vet Pharmacol Ther. 2023. PMID: 36691326

Cannabidiol and cannabidiolic acid: Preliminary in vitro evaluation of metabolism and drug-drug interactions involving canine cytochrome P-450, UDP-glucuronosyltransferase, and P-glycoprotein.

Court MH, Mealey KL, Burke NS, Jimenez TP, Zhu Z, Wakshlag JJ. Court MH, et al. J Vet Pharmacol Ther. 2024 Jan;47(1):1-13. doi: 10.1111/jvp.13403. Epub 2023 Jul 19. J Vet Pharmacol Ther. 2024. PMID: 37469115

Pharmacogenomics of poor drug metabolism in greyhounds: Canine P450 oxidoreductase genetic variation, breed heterogeneity, and functional characterization.

Martinez SE, Pandey AV, Perez Jimenez TE, Zhu Z, Court MH. Martinez SE, et al. Among authors: court mh. PLoS One. 2024 Feb 1;19(2):e0297191. doi: 10.1371/journal.pone.0297191. eCollection 2024. PLoS One. 2024. PMID: 38300925 Free PMC article.

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