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16,319 results

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Page 1
Covalent cofactor attachment to proteins: cytochrome c biogenesis.
Stevens JM, Uchida T, Daltrop O, Ferguson SJ. Stevens JM, et al. Biochem Soc Trans. 2005 Aug;33(Pt 4):792-5. doi: 10.1042/BST0330792. Biochem Soc Trans. 2005. PMID: 16042600 Review.
It confers diverse functions, including electron transfer, the binding and sensing of gases, and many types of catalysis. The majority of cofactors are non-covalently attached to proteins. There are, however, some proteins in which the cofactor binds covalently …
It confers diverse functions, including electron transfer, the binding and sensing of gases, and many types of catalysis. The majority of co …
Covalent Attachment of Horseradish Peroxidase to Single-Walled Carbon Nanotubes for Hydrogen Peroxide Detection.
Ledesma F, Nishitani S, Cunningham FJ, Hubbard JD, Yim D, Lui A, Chio L, Murali A, Landry MP. Ledesma F, et al. Adv Funct Mater. 2024 Aug 8;34(32):2316028. doi: 10.1002/adfm.202316028. Epub 2024 May 16. Adv Funct Mater. 2024. PMID: 39677986 Free PMC article.
Taken together, these results demonstrate successful covalent attachment of enzymes to SWCNTs while preserving both intrinsic SWCNT fluorescence and enzyme function. We anticipate this platform can be adapted to covalently attach other proteins of inte …
Taken together, these results demonstrate successful covalent attachment of enzymes to SWCNTs while preserving both intrinsic …
Covalent Attachment Strategies of Molecular Electrochromes for Enhancing Electrochromic Performance.
Anthony Raj MR, Humeniuk HV, Skene WG. Anthony Raj MR, et al. Chempluschem. 2025 Sep;90(9):e202500178. doi: 10.1002/cplu.202500178. Epub 2025 Aug 6. Chempluschem. 2025. PMID: 40765274 Free PMC article.
Focus is given to various strategies of covalently attaching molecular electrochromes to the device electrode for improving key electrochromic properties of contrast ratio and coloration efficiency. ...The overarching goal is to provide useful insight that can be le …
Focus is given to various strategies of covalently attaching molecular electrochromes to the device electrode for improving ke …
Covalent Attachment of Horseradish Peroxidase to Single-Walled Carbon Nanotubes for Hydrogen Peroxide Detection.
Ledesma F, Nishitani S, Cunningham FJ, Hubbard JD, Yim D, Lui A, Chio L, Murali A, Landry MP. Ledesma F, et al. bioRxiv [Preprint]. 2023 Dec 15:2023.12.14.571773. doi: 10.1101/2023.12.14.571773. bioRxiv. 2023. Update in: Adv Funct Mater. 2024 Aug 8;34(32):2316028. doi: 10.1002/adfm.202316028. PMID: 38168430 Free PMC article. Updated. Preprint.
Taken together, these results demonstrate successful covalent attachment of enzymes to SWCNTs while preserving both intrinsic SWCNT fluorescence and enzyme function. We anticipate this platform can be adapted to covalently attach other proteins of inte …
Taken together, these results demonstrate successful covalent attachment of enzymes to SWCNTs while preserving both intrinsic …
Covalent attachment of resveratrol to stainless steel toward the development of a resveratrol-releasing bare-metal stent.
Creasey HN, Brandel EZ, Nguyen R, Bashore MJ, Jones CM. Creasey HN, et al. J Biomed Mater Res B Appl Biomater. 2020 Jul;108(5):2344-2353. doi: 10.1002/jbm.b.34568. Epub 2020 Jan 29. J Biomed Mater Res B Appl Biomater. 2020. PMID: 31994825
Herein, we describe the covalent attachment of resveratrol, a naturally occurring antioxidant, to the surface of stainless-steel as a model for designing a novel bare-metal stent to treat coronary artery disease. ...Resveratrol can displace these hydrocarbons in apr …
Herein, we describe the covalent attachment of resveratrol, a naturally occurring antioxidant, to the surface of stainless-ste …
Covalent Attachment of Active Enzymes to Upconversion Phosphors Allows Ratiometric Detection of Substrates.
Burgess L, Wilson H, Jones AR, Harvey P, Natrajan LS, Hay S. Burgess L, et al. Chemistry. 2020 Nov 20;26(65):14817-14822. doi: 10.1002/chem.202001974. Epub 2020 Oct 16. Chemistry. 2020. PMID: 32476171 Free PMC article.
Here, UCPs were capped with functionalized silica in order to provide a surface to covalently conjugate proteins with surface-accessible cysteines. Variants of green fluorescent protein (GFP) and the flavoenzyme pentaerythritol tetranitrate reductase (PETNR) were then a …
Here, UCPs were capped with functionalized silica in order to provide a surface to covalently conjugate proteins with surface-accessi …
Comparison of Attachment and Antibacterial Activity of Covalent and Noncovalent Lysozyme-Functionalized Single-Walled Carbon Nanotubes.
Noor MM, Goswami J, Davis VA. Noor MM, et al. ACS Omega. 2020 Jan 27;5(5):2254-2259. doi: 10.1021/acsomega.9b03387. eCollection 2020 Feb 11. ACS Omega. 2020. PMID: 32064386 Free PMC article.
However, there has not been a direct comparison of the covalent and noncovalent methods for creating them. In this work, single-walled carbon nanotubes (SWNT) were functionalized with LSZ using both noncovalent adsorption and covalent attachment via N-ethyl-N …
However, there has not been a direct comparison of the covalent and noncovalent methods for creating them. In this work, single-walle …
Enhancing Membrane Permeability of Fluorescein-Type Chromophore Through Covalent Attachment of Chlorinated Dodecaborate.
Nakamura H, Yamamoto S, Kawamura YK, Kitazawa T, Kimura M, Kitazawa Y. Nakamura H, et al. Molecules. 2024 Nov 17;29(22):5416. doi: 10.3390/molecules29225416. Molecules. 2024. PMID: 39598805 Free PMC article.
In this study, we investigated the effect of covalently attaching chlorinated dodecaborate moiety [B(12)Cl(11)O-](2-) to 6-carboxyfluorescein (6-FAM) (3) via a PEG3 linker to form conjugate (4). We compared the membrane permeability of this covalent conjugate …
In this study, we investigated the effect of covalently attaching chlorinated dodecaborate moiety [B(12)Cl(11)O-](2-) to 6-car …
Assessing the Covalent Attachment and Energy Transfer Capabilities of Upconverting Phosphors With Cofactor Containing Bioactive Enzymes.
Burgess L, Wilson H, Jones AR, Hay S, Natrajan LS. Burgess L, et al. Front Chem. 2020 Dec 21;8:613334. doi: 10.3389/fchem.2020.613334. eCollection 2020. Front Chem. 2020. PMID: 33409268 Free PMC article.
Examples of biosensors utilizing the apparent energy transfer of UCPs and nanophosphors (UCNPs) with biomolecules have started to appear in the literature but very few exploit the covalent anchoring of the biomolecule to the surface of the UCP to improve the sensitivity of …
Examples of biosensors utilizing the apparent energy transfer of UCPs and nanophosphors (UCNPs) with biomolecules have started to appear in …
Direct covalent attachment of fluorescent molecules on plasma polymerized nanoparticles: a simplified approach for biomedical applications.
Haidar LL, Wang Y, Gilmour AD, Austria E Jr, Boumelhem BB, Aziz Khan N, Fadzil AA, Fraser ST, Bilek MMM, Akhavan B. Haidar LL, et al. J Mater Chem B. 2025 Jan 29;13(5):1666-1680. doi: 10.1039/d4tb01515k. J Mater Chem B. 2025. PMID: 39717992
While covalent attachment offers stability, it often entails laborious multi-step wet-chemistry processes. This work demonstrates that plasma polymerised nanoparticles (PPNs) can directly and covalently attach fluorescent molecules with no need for add …
While covalent attachment offers stability, it often entails laborious multi-step wet-chemistry processes. This work demonstra …
16,319 results
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