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Page 1
Metabolomics for the Diagnosis of Secondary Infections in Critically Ill Patients With COVID-19.
McCreath G, Regnault C, Blackburn GJ, Daly R, Leanord AT, Whitfield PD, Roe AJ, Davidson A, Watson MJ, Sim MAB. McCreath G, et al. Crit Care Explor. 2025 Nov 6;7(11):e1336. doi: 10.1097/CCE.0000000000001336. eCollection 2025 Nov 1. Crit Care Explor. 2025. PMID: 41195955 Free PMC article.
OBJECTIVES: Secondary infections are a common occurrence in critically ill COVID-19 patients. These are difficult to identify, and antibiotic usage is high in this population. ...CONCLUSIONS: Metabolomic profiling of critically ill COVID-19 shows promi …
OBJECTIVES: Secondary infections are a common occurrence in critically ill COVID-19 patients. These are difficult to identify, …
The effect of inflammatory proteins on COVID-19 is mediated by blood metabolites: A Mendelian randomization study.
Chen Y, Chen C. Chen Y, et al. Medicine (Baltimore). 2025 Mar 14;104(11):e41852. doi: 10.1097/MD.0000000000041852. Medicine (Baltimore). 2025. PMID: 40101060 Free PMC article.
Therefore, the purpose of the present study is to investigate the causal relationship between inflammatory proteins and COVID-19 and to identify and quantify the role of blood metabolites as potential mediators. ...The results of mediated MR showed that Betaine …
Therefore, the purpose of the present study is to investigate the causal relationship between inflammatory proteins and COVID-19 …
Metabolomic profiling of COVID-19 using serum and urine samples in intensive care and medical ward cohorts.
Tristán AI, Jiménez-Luna C, Abreu AC, Arrabal-Campos FM, Salmerón ADM, Rodríguez FI, Maresca MÁR, García AB, Melguizo C, Prados J, Fernández I. Tristán AI, et al. Sci Rep. 2024 Oct 10;14(1):23713. doi: 10.1038/s41598-024-74641-9. Sci Rep. 2024. PMID: 39390047 Free PMC article.
The COVID-19 pandemic remains a significant global health threat, with uncertainties persisting regarding the factors determining whether individuals experience mild symptoms, severe conditions, or succumb to the disease. This study presents an NMR metabolomics-base …
The COVID-19 pandemic remains a significant global health threat, with uncertainties persisting regarding the factors determin …
Boosting humoral and cellular immunity with enhanced STING activation by hierarchical mesoporous metal-organic framework adjuvants.
Huang C, Zhi X, Ye T, Wang X, Li K, Li Y, Zhang Q, Jiang L, Ding X. Huang C, et al. J Control Release. 2024 Jun;370:691-706. doi: 10.1016/j.jconrel.2024.05.010. Epub 2024 May 15. J Control Release. 2024. PMID: 38723671
Here, we designed hierarchical mesoporous MOF-801 (HM801) using a Cocamidopropyl betaine (CAPB) and a Pluronics F127 in an aqueous phase system. Meanwhile, we synthesized a novel SARS-CoV-2 nanovaccine (R@M@HM801) with a high loading capacity for both …
Here, we designed hierarchical mesoporous MOF-801 (HM801) using a Cocamidopropyl betaine (CAPB) and a Pluronics F127 in an aqueous ph …
Betaine prevents cognitive dysfunction by suppressing hippocampal microglial activation in chronic social isolated male mice.
Shi MM, Xu XF, Sun QM, Luo M, Liu DD, Guo DM, Chen L, Zhong XL, Xu Y, Cao WY. Shi MM, et al. Phytother Res. 2023 Oct;37(10):4755-4770. doi: 10.1002/ptr.7944. Epub 2023 Jul 15. Phytother Res. 2023. PMID: 37846157
Chronic social isolation (SI) stress, which became more prevalent during the COVID-19 pandemic, contributes to abnormal behavior, including mood changes and cognitive impairment. Known as a functional nutrient, betaine has potent antioxidant and anti-inflamma …
Chronic social isolation (SI) stress, which became more prevalent during the COVID-19 pandemic, contributes to abnormal behavi …
Integrated NMR and MS Analysis of the Plasma Metabolome Reveals Major Changes in One-Carbon, Lipid, and Amino Acid Metabolism in Severe and Fatal Cases of COVID-19.
Gama-Almeida MC, Pinto GDA, Teixeira L, Hottz ED, Ivens P, Ribeiro H, Garrett R, Torres AG, Carneiro TIA, Barbalho BO, Ludwig C, Struchiner CJ, Assunção-Miranda I, Valente APC, Bozza FA, Bozza PT, Dos Santos GC Jr, El-Bacha T. Gama-Almeida MC, et al. Metabolites. 2023 Jul 24;13(7):879. doi: 10.3390/metabo13070879. Metabolites. 2023. PMID: 37512587 Free PMC article.
Brazil has the second-highest COVID-19 death rate worldwide, and Rio de Janeiro is among the states with the highest rate in the country. ...COVID-19 patients were grouped into survivors (n = 18) and non-survivors (n = 17). Choline-related metabolites, …
Brazil has the second-highest COVID-19 death rate worldwide, and Rio de Janeiro is among the states with the highest rate in t …
Development of an optimized colorimetric RT-LAMP for SARS-CoV-2 assay with enhanced procedure controls for remote diagnostics.
Raddatz BW, Kim EYS, Imamura LM, Steil GJ, Santiago EB, Soares SPT, Ribeiro VHA, de Almeida BMM, Rogal SR Jr, Figueredo MVM. Raddatz BW, et al. Sci Rep. 2022 Dec 11;12(1):21424. doi: 10.1038/s41598-022-25872-1. Sci Rep. 2022. PMID: 36503901 Free PMC article.
In this paper, we developed an optimized colorimetric Reverse Transcriptase Loop-Mediated Isothermal Amplification (RT-LAMP) Point-of-Care test using a portable device to diagnose COVID-19. Variables such as concentration of primers, magnesium sulfate, betaine …
In this paper, we developed an optimized colorimetric Reverse Transcriptase Loop-Mediated Isothermal Amplification (RT-LAMP) Point-of-Care t …
Insight into the microplastics release from disposable face mask: Simulated environment and removal strategy.
Jiang H, Su J, Zhang Y, Bian K, Wang Z, Wang H, Wang C. Jiang H, et al. Chemosphere. 2022 Dec;309(Pt 1):136748. doi: 10.1016/j.chemosphere.2022.136748. Epub 2022 Oct 6. Chemosphere. 2022. PMID: 36209868 Free PMC article.
The fight against the COVID-19 epidemic significantly raises the global demand for personal protective equipment, especially disposable face masks (DFMs). ...Considering the risk of MPs released from DFMs to the environment, we innovatively established a novel flota …
The fight against the COVID-19 epidemic significantly raises the global demand for personal protective equipment, especially d …
The Effect of Dietary Methyl-Donor Intake and Other Lifestyle Factors on Cancer Patients in Hungary.
Kiss E, Hajdu A, Forika G, Dank M, Krenacs T, Nemeth Z. Kiss E, et al. Cancers (Basel). 2022 Sep 13;14(18):4432. doi: 10.3390/cancers14184432. Cancers (Basel). 2022. PMID: 36139592 Free PMC article.
Their deficiency can lead to several symptoms and diseases-even to severe SARS-CoV-2 infection. We aimed to explore the potential protective effect of methyl-donor intake in breast, colorectal and pancreatic cancer by patient follow up. ...The total intake of …
Their deficiency can lead to several symptoms and diseases-even to severe SARS-CoV-2 infection. We aimed to explore the …
Identification of Prognostic Metabolomic Biomarkers at the Interface of Mortality and Morbidity in Pre-Existing TB Cases Infected With SARS-CoV-2.
Diboun I, Cyprian FS, Anwardeen NR, Yassine HM, Elrayess MA, Rahmoon SM, Sayed SK, Schuchardt S, Khatib M, Bansal D, Farag EABA, Emara MM, Abdallah AM. Diboun I, et al. Front Cell Infect Microbiol. 2022 Jul 22;12:929689. doi: 10.3389/fcimb.2022.929689. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35937683 Free PMC article.
In this study, we used a metabolomics analysis to identify potential biomarkers that aid in the prognosis of COVID-19 morbidity and mortality in post-TB infected patients. This analysis involved blood samples from 155 SARS-CoV-2 infected adults, …
In this study, we used a metabolomics analysis to identify potential biomarkers that aid in the prognosis of COVID-19 morbidit …
16 results