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MoMo30 Binds to SARS-CoV-2 Spike Variants and Blocks Infection by SARS-CoV-2 Pseudovirus.
DeBarros K, Khan M, Coleman M, Bond VC, Floyd V, Gbodossou E, Diop A, Krumpe LRH, O'Keefe BR, Powell MD. DeBarros K, et al. Viruses. 2024 Sep 7;16(9):1433. doi: 10.3390/v16091433. Viruses. 2024. PMID: 39339909 Free PMC article.
MoMo30 is an antiviral protein isolated from aqueous extracts of Momordica balsamina L. (Senegalese bitter melon). Previously, we demonstrated MoMo30's antiviral activity against HIV-1. Here, we explore whether MoMo30 has antiviral activity against the COV …
MoMo30 is an antiviral protein isolated from aqueous extracts of Momordica balsamina L. (Senegalese bitter melon). Prev …
The ribosome-inactivating proteins MAP30 and Momordin inhibit SARS-CoV-2.
Watts NR, Eren E, Palmer I, Huang PL, Huang PL, Shoemaker RH, Lee-Huang S, Wingfield PT. Watts NR, et al. PLoS One. 2023 Jun 29;18(6):e0286370. doi: 10.1371/journal.pone.0286370. eCollection 2023. PLoS One. 2023. PMID: 37384752 Free PMC article.
The continuing emergence of SARS-CoV-2 variants has highlighted the need to identify additional points for viral inhibition. Ribosome inactivating proteins (RIPs), such as MAP30 and Momordin which are derived from bitter melon (Momordica …
The continuing emergence of SARS-CoV-2 variants has highlighted the need to identify additional points for viral inhibi …
Promising roles of Zingiber officinale roscoe, Curcuma longa L., and Momordica charantia L. as immunity modulators against COVID-19: A bibliometric analysis.
Sheikh HI, Zakaria NH, Abdul Majid FA, Zamzuri F, Fadhlina A, Hairani MAS. Sheikh HI, et al. J Agric Food Res. 2023 Dec;14:100680. doi: 10.1016/j.jafr.2023.100680. Epub 2023 Jun 12. J Agric Food Res. 2023. PMID: 37346755 Free PMC article.
Zingiber officinale, Curcuma longa, and Momordica charantia are medicinal plants that are commonly used in the form of herbal tea, which is formulated to strengthen the immune system, especially against COVID-19 infection. ...This review paper therefor …
Zingiber officinale, Curcuma longa, and Momordica charantia are medicinal plants that are commonly used in the form of herbal …
In-silico studies of Momordica charantia extracts as potential candidates against SARS-CoV-2 targeting human main protease enzyme (M(pro)).
Adedayo A, Famuti A. Adedayo A, et al. Inform Med Unlocked. 2023;38:101216. doi: 10.1016/j.imu.2023.101216. Epub 2023 Mar 11. Inform Med Unlocked. 2023. PMID: 36935867 Free PMC article.
Momordica charintia, a well-known plant called bitter melon, has been shown to have antibacterial, anti-diabetic, and antiviral properties against HIV infection. ...From the results obtained, it can be concluded that Quercetin 3-galactopyranoside, Rutin, and …
Momordica charintia, a well-known plant called bitter melon, has been shown to have antibacterial, anti-diabetic, and a …
Comparison study of Beninese and Chinese herbal medicines in treating COVID-19.
Houeze EA, Wang Y, Zhou Q, Zhang H, Wang X. Houeze EA, et al. J Ethnopharmacol. 2023 May 23;308:116172. doi: 10.1016/j.jep.2023.116172. Epub 2023 Feb 10. J Ethnopharmacol. 2023. PMID: 36773790 Free PMC article.
Chinese and Beninese herbal medicine are similar in that they have the same targets and pathways in inflammation and oxidative stress relief. Mild COVID-19-related targets come from C. aurantiifolia and M. charantia, and severe COVID-19-related …
Chinese and Beninese herbal medicine are similar in that they have the same targets and pathways in inflammation and oxidative stress relief …
Molecular Docking of Phytochemical Compounds of Momordica charantia as Potential Inhibitors against SARS-CoV-2.
Evary YM, Masyita A, Kurnianto AA, Asri RM, Rifai Y. Evary YM, et al. Infect Disord Drug Targets. 2022;22(3):e130122200221. doi: 10.2174/1871526522666220113143358. Infect Disord Drug Targets. 2022. PMID: 35049440
BACKGROUND: Coronavirus disease 2019 (COVID-19) has been recently declared as a global public health emergency, where the infection is caused by SARS-CoV-2. ...CONCLUSION: Our result indicates that these molecules can be further explored as prom …
BACKGROUND: Coronavirus disease 2019 (COVID-19) has been recently declared as a global public health emergency, where the infe …
Virtual screening of functional foods and dissecting their roles in modulating gene functions to support post COVID-19 complications.
Afroz S, Fairuz S, Joty JA, Uddin MN, Rahman MA. Afroz S, et al. J Food Biochem. 2021 Dec;45(12):e13961. doi: 10.1111/jfbc.13961. Epub 2021 Oct 22. J Food Biochem. 2021. PMID: 34676581 Free PMC article.
COVID-19 has become the focal point since 2019 after the outbreak of coronavirus disease. ...Among the chosen functional foods, black cumin, fenugreek, garlic, ginger, turmeric, bitter melon, and Indian pennywort were found to modulate the actions. Res …
COVID-19 has become the focal point since 2019 after the outbreak of coronavirus disease. ...Among the chosen functional foods …
Targeting novel coronavirus SARS-CoV-2 spike protein with phytoconstituents of Momordica charantia.
Singh SK, Singh S, Singh R. Singh SK, et al. J Ovarian Res. 2021 Sep 27;14(1):126. doi: 10.1186/s13048-021-00872-3. J Ovarian Res. 2021. PMID: 34579761 Free PMC article.
Thus, there is an urgent need to find drugs that treat COVID-19 and save human lives. Hence, in this study, we identified phytoconstituents of an edible vegetable, Bitter melon (Momordica charantia), that affect the SARS-CoV …
Thus, there is an urgent need to find drugs that treat COVID-19 and save human lives. Hence, in this study, we identified phyt …
Promising traditional Indian medicinal plants for the management of novel Coronavirus disease: A systematic review.
Singh RS, Singh A, Kaur H, Batra G, Sarma P, Kaur H, Bhattacharyya A, Sharma AR, Kumar S, Upadhyay S, Tiwari V, Avti P, Prakash A, Medhi B. Singh RS, et al. Phytother Res. 2021 Aug;35(8):4456-4484. doi: 10.1002/ptr.7150. Epub 2021 Jun 16. Phytother Res. 2021. PMID: 34132429 Free PMC article.
Further, 36 randomized and nonrandomized registered clinical trials were also included that were aimed at evaluating the efficacy of herbal plants or their formulations in COVID-19 management. The antiviral, immunomodulatory, and thrombolytic activities of the tradi …
Further, 36 randomized and nonrandomized registered clinical trials were also included that were aimed at evaluating the efficacy of herbal …
Natural phyto, compounds as possible noncovalent inhibitors against SARS-CoV2 protease: computational approach.
Ogidigo JO, Iwuchukwu EA, Ibeji CU, Okpalefe O, Soliman MES. Ogidigo JO, et al. J Biomol Struct Dyn. 2022 Mar;40(5):2284-2301. doi: 10.1080/07391102.2020.1837681. Epub 2020 Oct 25. J Biomol Struct Dyn. 2022. PMID: 33103616 Free PMC article.
At present, there is no cure or vaccine for the devastating new highly infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has affected people globally. Herein, we identified potent phytocompounds from two antiviral plants Momordic …
At present, there is no cure or vaccine for the devastating new highly infectious severe acute respiratory syndrome coronavirus 2 (SARS …