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2020 2
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TIRTL-seq: deep, quantitative and affordable paired TCR repertoire sequencing.
Pogorelyy MV, Kirk AM, Adhikari S, Minervina AA, Sundararaman B, Vegesana K, Brice DC, Scott ZB; SJTRC Study Team; Thomas PG. Pogorelyy MV, et al. Nat Methods. 2026 Jan;23(1):56-64. doi: 10.1038/s41592-025-02907-9. Epub 2025 Nov 24. Nat Methods. 2026. PMID: 41286199 Free PMC article.
We benchmarked TIRTL-seq against state-of-the-art bulk TCR-seq and 10x Genomics Chromium technologies on longitudinal samples and identified severe acute respiratory syndrome coronavirus 2- and Epstein-Barr virus-specific clonal expansions after infection with distinct dyn …
We benchmarked TIRTL-seq against state-of-the-art bulk TCR-seq and 10x Genomics Chromium technologies on longitudinal samples and ide …
Single-cell RNA-sequencing highlights a curtailed NK cell function in convalescent COVID-19 pregnant women.
Salker MS, Abd Aziz NH, Prodan NC, Yang Z, Lankapalli AK, Lazar K, Shafiee MN, Kocak E, Ganesan H, Pal SS, Khalid O, Kasim NM, Kalok A, Fuad NA, Bissinger AL, Ganzenmueller T, Iftner T, Kagan KO, Ossowski S, Casadei N, Brucker SY, Riess O, Singh Y; Deutsche COVID-19 OMICS Initiative (DeCOI). Salker MS, et al. Front Immunol. 2025 Jun 30;16:1560391. doi: 10.3389/fimmu.2025.1560391. eCollection 2025. Front Immunol. 2025. PMID: 40661959 Free PMC article.
Further, scRNA-seq data revealed that infection with SARS-CoV-2 rewired the gene expression profile of NK, monocytes, CD4(+), CD8(+) effector T cells and antibody producing B cells in convalescent pregnant women. ...DISCUSSION: Overall, our study uncovers tha …
Further, scRNA-seq data revealed that infection with SARS-CoV-2 rewired the gene expression profile of NK, monocytes, C …
A portable, rapid isothermal amplification kit enabling naked eye detection of SARS-CoV-2 RNAs.
Park JH, Kim K, Lee B, Jang H, Kim MG. Park JH, et al. Talanta. 2025 Apr 1;285:127327. doi: 10.1016/j.talanta.2024.127327. Epub 2024 Dec 9. Talanta. 2025. PMID: 39657523
Since the coronavirus disease 2019 (COVID-19) pandemic, isothermal amplification techniques have attracted attention due to their higher sensitivity and specificity, compared with immunoassays, and their potential application for point-of-care testing (POCT). ...Usi …
Since the coronavirus disease 2019 (COVID-19) pandemic, isothermal amplification techniques have attracted attention due to th …
Retention of nickel, cobalt and chromium in skin at conditions mimicking intense hand hygiene practices using water, soap, and hand-disinfectant in vitro.
Vilela L, Schenk L, Julander A, Midander K. Vilela L, et al. J Occup Med Toxicol. 2024 Nov 6;19(1):44. doi: 10.1186/s12995-024-00442-5. J Occup Med Toxicol. 2024. PMID: 39506751 Free PMC article.
BACKGROUND: During the COVID-19 pandemic, increased hand hygiene practices using water, soap and hand disinfectants, became prevalent, particularly among frontline workers. This study investigates the impact of these practices on the skin's ability to retain the all …
BACKGROUND: During the COVID-19 pandemic, increased hand hygiene practices using water, soap and hand disinfectants, became pr …
TIRTL-seq: Deep, quantitative, and affordable paired TCR repertoire sequencing.
Pogorelyy MV, Kirk AM, Adhikari S, Minervina AA, Sundararaman B, Vegesana K, Brice DC, Scott ZB; SJTRC Study Team; Thomas PG. Pogorelyy MV, et al. bioRxiv [Preprint]. 2024 Oct 31:2024.09.16.613345. doi: 10.1101/2024.09.16.613345. bioRxiv. 2024. Update in: Nat Methods. 2026 Jan;23(1):56-64. doi: 10.1038/s41592-025-02907-9. PMID: 39345544 Free PMC article. Updated. Preprint.
We benchmarked TIRTL-seq against state-of-the-art 5'RACE bulk TCR-seq and 10x Genomics Chromium technologies on longitudinal samples. We show that TIRTL-seq is able to quantitatively identify expanding and contracting clonotypes between timepoints while providing accurate …
We benchmarked TIRTL-seq against state-of-the-art 5'RACE bulk TCR-seq and 10x Genomics Chromium technologies on longitudinal samples. …
Digitally Guided Advanced Prosthodontic Rehabilitation for Post-COVID-19 Mucormycosis Using Patient-Specific Implants: A Case Report.
Surana M, Tewary S, Mishra N, Jain V, Sanyal P. Surana M, et al. Cureus. 2024 Jul 17;16(7):e64729. doi: 10.7759/cureus.64729. eCollection 2024 Jul. Cureus. 2024. PMID: 39156396 Free PMC article.
This case report describes the prosthodontic rehabilitation of a middle-aged male patient who underwent bilateral low-level maxillectomy due to post-COVID-19 mucormycosis. The oronasal communication was closed using an anterior base tongue flap. ...A clasp assembly …
This case report describes the prosthodontic rehabilitation of a middle-aged male patient who underwent bilateral low-level maxillectomy due …
Impact of COVID-19 on temporal trends and health risks of urinary metal concentrations among residents of Guangzhou, China.
Liao J, Huang R, Jia X, He J, Li Q, Li X, Yuan J, Tan L. Liao J, et al. Environ Res. 2024 Nov 15;261:119705. doi: 10.1016/j.envres.2024.119705. Epub 2024 Jul 29. Environ Res. 2024. PMID: 39084505
The total metal ion concentrations in the urine of the population did not change significantly between 2018 and 2019. With the onset of the COVID-19 pandemic in 2020, urinary total metal ion concentrations began to decline dramatically, reaching their lowest level i …
The total metal ion concentrations in the urine of the population did not change significantly between 2018 and 2019. With the onset of the …
In silico analysis of the impact of toxic metals on COVID-19 complications: molecular insights.
Živanović J, Baralić K, Živančević K, Božić D, Marić Đ, Miljaković EA, Đorđević AB, Ćurčić M, Bulat Z, Antonijević B, Đukić-Ćosić D. Živanović J, et al. Arh Hig Rada Toksikol. 2024 Jun 29;75(2):102-109. doi: 10.2478/aiht-2024-75-3819. eCollection 2024 Jun 1. Arh Hig Rada Toksikol. 2024. PMID: 38963144 Free PMC article.
The aim of this study was to answer this question with in silico toxicogenomic methods that can provide molecular insights into COVID-19 complications owed to exposure to arsenic, cadmium, lead, mercury, nickel, and chromium. ...Biological processes, molecula …
The aim of this study was to answer this question with in silico toxicogenomic methods that can provide molecular insights into COVID …
Green and Versatile High-Throughput Microwell Oxidation-Based Spectrophotometric Methods for Determination of Galidesivir in Capsules.
Darwish IA, Alzoman NZ. Darwish IA, et al. J AOAC Int. 2024 Oct 1;107(5):727-734. doi: 10.1093/jaoacint/qsae047. J AOAC Int. 2024. PMID: 38870529
BACKGROUND: Galidesivir (GDV) is a promising new antiviral drug for the potent and safe treatment of a broad spectrum of viral diseases, including COVID-19. In the literature, no analytical method exists for the determination of GDV in bulk and dosage form. ...METHO …
BACKGROUND: Galidesivir (GDV) is a promising new antiviral drug for the potent and safe treatment of a broad spectrum of viral diseases, inc …
Assessment of genotoxicity of air pollution in urban areas using an integrated model of passive biomonitoring.
Campos CF, Santos VSV, Campos Júnior EO, da Costa Estrela D, Pires LP, Meza Bravo JV, Pereira BB. Campos CF, et al. Environ Pollut. 2024 Aug 15;355:124219. doi: 10.1016/j.envpol.2024.124219. Epub 2024 May 24. Environ Pollut. 2024. PMID: 38797347
T. pallida was strategically planted at the leading urban intersections in Uberlandia, Brazil. During COVID-19 pandemic lockdowns, we compared indicators such as physical, biological, and traffic data at different intersections in residential and commercial zones. . …
T. pallida was strategically planted at the leading urban intersections in Uberlandia, Brazil. During COVID-19 pandemic lockdo …
33 results