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2020 27
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Synthesis and Antiviral Evaluation of 5-(4-Aryl-1,3-butadiyn-1-yl)-uridines and Their Phosphoramidate Pronucleotides.
Saillard E, Bourzikat O, Assa K, Roy V, Agrofoglio LA. Saillard E, et al. Molecules. 2024 Dec 29;30(1):96. doi: 10.3390/molecules30010096. Molecules. 2024. PMID: 39795153 Free PMC article.
These compounds were synthesized using Sonogashira palladium-catalyzed reactions and nickel-copper-catalyzed C-H activation between various alkynes, yielding between 25% and 67%. The antiviral activities of obtained compounds were measured through HTS against RNA viruses i …
These compounds were synthesized using Sonogashira palladium-catalyzed reactions and nickel-copper-catalyzed C-H activation between v …
Identifying people with post-COVID condition using linked, population-based administrative health data from Manitoba, Canada: prevalence and predictors in a cohort of COVID-positive individuals.
Katz A, Ekuma O, Enns JE, Cavett T, Singer A, Sanchez-Ramirez DC, Keynan Y, Lix L, Walld R, Yogendran M, Nickel NC, Urquia M, Star L, Olafson K, Logsetty S, Spiwak R, Waruk J, Matharaarachichi S. Katz A, et al. BMJ Open. 2025 Jan 9;15(1):e087920. doi: 10.1136/bmjopen-2024-087920. BMJ Open. 2025. PMID: 39788761 Free article.
OBJECTIVE: Many individuals exposed to SARS-CoV-2 experience long-term symptoms as part of a syndrome called post-COVID condition (PCC). ...Receiving 1+ doses of the COVID-19 vaccine (one dose, aOR 0.80, 95% CI 0.74 to 0.86; two doses, aO …
OBJECTIVE: Many individuals exposed to SARS-CoV-2 experience long-term symptoms as part of a syndrome called post-CO …
Multicenter Evaluation of the QIAstat-Dx and the BioFire Multiplex Panel Tests for the Detection of Respiratory Pathogens.
Gosert R, Koller R, Meyer J, Dräger S, Ramette A, Bingisser R, Nickel CH, Bassetti S, Sutter ST, Keller PM, Bittel P, Leuzinger K. Gosert R, et al. J Med Virol. 2024 Dec;96(12):e70129. doi: 10.1002/jmv.70129. J Med Virol. 2024. PMID: 39711468 Free PMC article.
Most significant differences were found for the detection of adenovirus, human coronaviruses, respiratory syncytial virus, human rhinovirus/enterovirus and SARS-CoV-2 (kappa-score: 0.67-0.91). Co-detections of respiratory pathogens were identified in 47 cases …
Most significant differences were found for the detection of adenovirus, human coronaviruses, respiratory syncytial virus, human rhinovirus/ …
Organic compounds in valley fogwater in North and Mount Lebanon during COVID-19 period.
Khoury D, Jabali Y, Delhomme O, Al Makdessi N, Millet M. Khoury D, et al. Sci Total Environ. 2024 Dec 19;958:178108. doi: 10.1016/j.scitotenv.2024.178108. Online ahead of print. Sci Total Environ. 2024. PMID: 39705951
Phenols and acids are highly associated with PAHs and PCBs as well as with sulfate and heavy metals (manganese and nickel). This shows that their sources can be either atmospheric oxidation or vehicle exhaust. ...
Phenols and acids are highly associated with PAHs and PCBs as well as with sulfate and heavy metals (manganese and nickel). This show …
Improved recombinant expression of soluble cathepsin B and L in Escherichia coli.
Möller C, Rimkus N, Skala FFO, Merouze M, Böttcher D, Dörr M, Bornscheuer UT. Möller C, et al. Appl Microbiol Biotechnol. 2024 Dec 16;108(1):536. doi: 10.1007/s00253-024-13374-1. Appl Microbiol Biotechnol. 2024. PMID: 39680170 Free PMC article.
Cysteine cathepsins such as cathepsin B and L play an important role in numerous diseases like acute pancreatitis or SARS-CoV-2 and therefore have high potential for the development of new therapeutics. ...The enzymes were purified by immobilized nickel …
Cysteine cathepsins such as cathepsin B and L play an important role in numerous diseases like acute pancreatitis or SARS-CoV- …
A portable, rapid isothermal amplification kit enabling naked eye detection of SARS-CoV-2 RNAs.
Park JH, Kim K, Lee B, Jang H, Kim MG. Park JH, et al. Talanta. 2024 Dec 9;285:127327. doi: 10.1016/j.talanta.2024.127327. Online ahead of print. Talanta. 2024. PMID: 39657523
Since the coronavirus disease 2019 (COVID-19) pandemic, isothermal amplification techniques have attracted attention due to their higher sensitivity and specificity, compared with immunoassays, and their potential application for point-of-care testing (POCT). ...Usi …
Since the coronavirus disease 2019 (COVID-19) pandemic, isothermal amplification techniques have attracted attention due to th …
The utility of personal wearable data in long COVID and personalized patient care.
Enichen EJ, Heydari K, Wang S, Nickel GC, Kvedar JC. Enichen EJ, et al. NPJ Digit Med. 2024 Nov 18;7(1):326. doi: 10.1038/s41746-024-01341-z. NPJ Digit Med. 2024. PMID: 39557995 Free PMC article.
Radin et al.'s recent study on patients with long COVID demonstrates that personal wearable data can provide critical insight into complex conditions. ...
Radin et al.'s recent study on patients with long COVID demonstrates that personal wearable data can provide critical insight into co …
Highly Active Oxygen Evolution Reaction of NiMoO4 Sub-1 nm Nanowires Boosts Luminol Electrochemiluminescence.
Zang H, Wang DM, Dai WJ, Chen L, Wang YT, Wang Q, Wang Q, Chen GX, Li JJ, Xie JL, Zou HY, Huang CZ, Li YF, Zhen SJ. Zang H, et al. Small. 2024 Nov 12:e2407321. doi: 10.1002/smll.202407321. Online ahead of print. Small. 2024. PMID: 39530620
However, most of these materials are characterized by their nanoscale or microscale dimensions, resulting in relatively large sizes and low specific surface areas, which hinder the application of the luminol-H(2)O system. To address this challenge, nickel molybdate sub-1 n …
However, most of these materials are characterized by their nanoscale or microscale dimensions, resulting in relatively large sizes and low …
Retention of nickel, cobalt and chromium in skin at conditions mimicking intense hand hygiene practices using water, soap, and hand-disinfectant in vitro.
Vilela L, Schenk L, Julander A, Midander K. Vilela L, et al. J Occup Med Toxicol. 2024 Nov 6;19(1):44. doi: 10.1186/s12995-024-00442-5. J Occup Med Toxicol. 2024. PMID: 39506751 Free PMC article.
BACKGROUND: During the COVID-19 pandemic, increased hand hygiene practices using water, soap and hand disinfectants, became prevalent, particularly among frontline workers. ...The highest amounts of metal retained in skin were observed for exposure to nickel …
BACKGROUND: During the COVID-19 pandemic, increased hand hygiene practices using water, soap and hand disinfectants, became pr …
Metallomic analysis of urine from individuals with and without Covid-19 infection reveals extensive alterations in metal homeostasis.
Leal KNDS, Santos da Silva AB, Fonseca EKB, Moreira OBO, de Lemos LM, Leal de Oliveira MA, Stewart AJ, Arruda MAZ. Leal KNDS, et al. J Trace Elem Med Biol. 2024 Dec;86:127557. doi: 10.1016/j.jtemb.2024.127557. Epub 2024 Oct 28. J Trace Elem Med Biol. 2024. PMID: 39500269
In this study urinary excretion of several metals including calcium, cadmium, cobalt, copper, iron, magnesium, nickel, selenium, and zinc in Covid-19 patients (n=35) and control (n=60) individuals, spanning ages and sexes. ...The increase in calcium excretion …
In this study urinary excretion of several metals including calcium, cadmium, cobalt, copper, iron, magnesium, nickel, selenium, and …
170 results