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Page 1
Synthesis and Antiviral Evaluation of 5-(4-Aryl-1,3-butadiyn-1-yl)-uridines and Their Phosphoramidate Pronucleotides.
Saillard E, Bourzikat O, Assa K, Roy V, Agrofoglio LA. Saillard E, et al. Molecules. 2024 Dec 29;30(1):96. doi: 10.3390/molecules30010096. Molecules. 2024. PMID: 39795153 Free PMC article.
These compounds were synthesized using Sonogashira palladium-catalyzed reactions and nickel-copper-catalyzed C-H activation between various alkynes, yielding between 25% and 67%. The antiviral activities of obtained compounds were measured through HTS against RNA viruses i …
These compounds were synthesized using Sonogashira palladium-catalyzed reactions and nickel-copper-catalyzed C-H activation between v …
Au@Pt@Pd nanozymes based lateral flow immunoassay for quantitative detection of SARS-CoV-2 nucleocapsid protein in nasal swab samples.
Li C, Lu J, Xiang C, Zhang E, Tian X, Zhang L, Li T, Li C. Li C, et al. Mikrochim Acta. 2024 Nov 7;191(12):730. doi: 10.1007/s00604-024-06819-x. Mikrochim Acta. 2024. PMID: 39508966
Three-metal-core-shell nanoparticles (Au@Pt@PdNPs) providing excellent peroxidase-like activity were applied in lateral flow immunoassay (LFIA), designated as Au@Pt@Pd-LFIA, for detecting the nucleocapsid protein (NP) of severe acute respiratory syndrome coronavirus 2 (SARS …
Three-metal-core-shell nanoparticles (Au@Pt@PdNPs) providing excellent peroxidase-like activity were applied in lateral flow immunoassay (LF …
Chemically Synthesized 1,2,3,4,6-Pentakis-O-Galloyl-beta-D-Glucopyranoside Blocks SARS-CoV-2 Spike Interaction with Host ACE-2 Receptor.
Ezell J, Al-Horani RA. Ezell J, et al. Med Chem. 2024;20(10):986-991. doi: 10.2174/0115734064302693240711114948. Med Chem. 2024. PMID: 39041278
The synthesized molecule was evaluated using a SARS-CoV-2 spike trimer (S1 + S2) ACE2 inhibitor screening colorimetric assay kit, SARS-CoV- 2 spike S1 RBD ACE2 inhibitor screening assay kit, and a cellular neutralization assay using the S …
The synthesized molecule was evaluated using a SARS-CoV-2 spike trimer (S1 + S2) ACE2 inhibitor screening colorimetric …
Strengthening primary health care in low- and middle-income countries: furthering structural changes in the post-pandemic era.
Alegre JC, Sharma S, Cleghorn F, Avila C. Alegre JC, et al. Front Public Health. 2024 Feb 14;11:1270510. doi: 10.3389/fpubh.2023.1270510. eCollection 2023. Front Public Health. 2024. PMID: 38419816 Free PMC article.
Yet, investment in PHC is still insufficient and overall performance of PHC systems is weak in LMICs, resulting in increased vulnerability and poor health outcomes especially among marginalized populations. As countries recover from the COVID-19 pandemic, which expo …
Yet, investment in PHC is still insufficient and overall performance of PHC systems is weak in LMICs, resulting in increased vulnerability a …
Novel Bidentate Amine Ligand and the Interplay between Pd(II) and Pt(II) Coordination and Biological Activity.
Oliveira LS, Rosa LB, Affonso DD, Santos IA, Da Silva JC, Rodrigues GC, Harris M, Jardim ACG, Nakahata DH, Sabino JR, de Carvalho JE, Miguel DC, Ruiz ALTG, Abbehausen C. Oliveira LS, et al. Chembiochem. 2024 Mar 15;25(6):e202300696. doi: 10.1002/cbic.202300696. Epub 2024 Feb 12. Chembiochem. 2024. PMID: 38146865
The ligand and the Pd(II) complex showed good anti-SARS-CoV-2 activity with around 65 % reduction in viral replication at a concentration of 50 muM....
The ligand and the Pd(II) complex showed good anti-SARS-CoV-2 activity with around 65 % reduction in viral replication …
Collectively achieving primary health care and educational goals through school-based platforms: financing solutions for intersectoral collaboration.
Schiff M, Jha A, Walker D, Gonzalez-Pier E. Schiff M, et al. Front Public Health. 2023 Nov 28;11:1241594. doi: 10.3389/fpubh.2023.1241594. eCollection 2023. Front Public Health. 2023. PMID: 38089030 Free PMC article.
Enhancing this collaboration is essential to realize mutually beneficial results, especially following the COVID-19 pandemic, which severely impacted health and education outcomes globally and highlighted the importance of resilient, domestically funded systems for …
Enhancing this collaboration is essential to realize mutually beneficial results, especially following the COVID-19 pandemic, …
Asymmetric effects of crude oil prices and USD exchange rate on precious metals returns:Evidence from pre and during COVID-19 outbreak.
Wang Y, Chen J, Ren X. Wang Y, et al. Heliyon. 2023 Nov 2;9(11):e21996. doi: 10.1016/j.heliyon.2023.e21996. eCollection 2023 Nov. Heliyon. 2023. PMID: 38027582 Free PMC article.
Using quantile regression, this paper examines the impact of oil prices and the US dollar exchange rate on gold, silver, platinum, and palladium from January 1, 2013 to 5 May 2023. Oil prices positively affect precious metals returns, and positive and negative oil price sh …
Using quantile regression, this paper examines the impact of oil prices and the US dollar exchange rate on gold, silver, platinum, and pa …
Impact of the COVID-19 pandemic on routine HIV care and antiretroviral treatment outcomes in Kenya: A nationally representative analysis.
Kimanga DO, Makory VNB, Hassan AS, Ngari F, Ndisha MM, Muthoka KJ, Odero L, Omoro GO, Aoko A, Ng'ang'a L. Kimanga DO, et al. PLoS One. 2023 Nov 27;18(11):e0291479. doi: 10.1371/journal.pone.0291479. eCollection 2023. PLoS One. 2023. PMID: 38011132 Free PMC article.
Date of ART initiation was stratified into pre-COVID-19 (April 2018 -March 2019 and April 2019 -March 2020) and COVID-19 (April 2020 -March 2021) periods. ...Continued monitoring to assess long-term impact of the COVID-19 pandemic on HIV …
Date of ART initiation was stratified into pre-COVID-19 (April 2018 -March 2019 and April 2019 -March 2020) and COVID- …
Getting ready for reduced donor dependency: the co-financing of family planning commodities.
Jha A, Kolesar RJ, Comas S, Gribble J, Ugaz J, Gonzalez-Pier E. Jha A, et al. Health Policy Plan. 2024 Jan 9;39(1):87-93. doi: 10.1093/heapol/czad106. Health Policy Plan. 2024. PMID: 37987720 Free PMC article.
Family planning (FP) programmes in low and lower-middle income countries are confronting the dual impact of reduced external donor commitments and stagnant or reduced domestic financing, worsened by economic consequences of the COVID-19 pandemic. Co-financing-a dono …
Family planning (FP) programmes in low and lower-middle income countries are confronting the dual impact of reduced external donor commitmen …
AIEgen orthopalladated hybrid polymers for efficient inactivation of the total coliforms in urban wastewater.
Sessa L, Diana R, Gentile FS, Mazzaglia F, Panunzi B. Sessa L, et al. Sci Rep. 2023 Sep 22;13(1):15790. doi: 10.1038/s41598-023-41315-x. Sci Rep. 2023. PMID: 37737240 Free PMC article.
Monitorable AIE polymers with a bioactive pattern are employed in advanced biomedical applications such as functional coatings, theranostic probes, and implants. After the global COVID-19 pandemic, interest in developing surfaces with superior antimicrobial, antipro …
Monitorable AIE polymers with a bioactive pattern are employed in advanced biomedical applications such as functional coatings, theranostic …
48 results