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2020 21
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253 results

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Page 1
Hybrid dielectric-graphene nanostructured SERS substrates for antibody sensing.
Redolat J, Sinusia Lozano M, Camarena Pérez M, González-Llácer I, Zorina S, Zafra E, Alonso Chornet M, Díaz-Escobar E, Gómez VJ, Martínez A, Pinilla-Cienfuegos E. Redolat J, et al. Nanoscale Adv. 2025 Nov 18. doi: 10.1039/d5na00847f. Online ahead of print. Nanoscale Adv. 2025. PMID: 41368593 Free PMC article.
We present a hybrid surface-enhanced Raman spectroscopy (SERS) platform based on a nanostructured silicon substrate integrated with functionalized graphene for the selective detection of biomolecules such as prolactin and SARS-CoV-2 antibodies. The hig …
We present a hybrid surface-enhanced Raman spectroscopy (SERS) platform based on a nanostructured silicon substrate integrated with f …
Early lymph node T follicular helper cell signalling hub drives influenza vaccine response in an ancestrally diverse cohort.
Siu JHY, Coelho S, Palomeras A, Belij-Rammerstorfer S, Barman N, Lee CH, Ströbel T, Thorpe CJ, Kaur C, Cole T, Remmert N, Fowler J, Pledger S, Dooley KB, Chan T, Höschler K, Zambon M, Opoka D, Szommer T, Kim SJ, Kumar V, Vanderslott S, Kaleebu P, Milicic A, Palmer DB, Lambe T, Marsden BD, Koohy H, Coles M, Dendrou CA, Pollock KM. Siu JHY, et al. EBioMedicine. 2025 Nov 28;122:106036. doi: 10.1016/j.ebiom.2025.106036. Online ahead of print. EBioMedicine. 2025. PMID: 41317665 Free article.
INTERPRETATION: Early CD4(+) Tfh coordination in draining lymphoid tissue underpins robust responses to adjuvanted influenza vaccine that transcend ancestral inter-individual variation in young adults, with implications for vaccine design in ancestrally-diverse populations. FUNDI …
INTERPRETATION: Early CD4(+) Tfh coordination in draining lymphoid tissue underpins robust responses to adjuvanted influenza vaccine that tr …
Features and In Vitro Assessment of Antiviral Activity of Organic Coatings Doped with Silver-Based Compounds Against Human Coronavirus.
Zaczek-Moczydłowska MA, Kopyciński B, Hryniszyn A, Osadnik M, Czech A, Pęcak K, Markowska A, Ghavami S, Matus K, Langer E, Łos MJ. Zaczek-Moczydłowska MA, et al. Int J Mol Sci. 2025 Nov 15;26(22):11068. doi: 10.3390/ijms262211068. Int J Mol Sci. 2025. PMID: 41303549 Free PMC article.
Implementation of novel antiviral coatings and textiles, which can be utilised in the production of personal protective equipment, has the potential to enhance public health security against future pandemic outbreaks. Respiratory viruses, particularly SARS-CoV-2 …
Implementation of novel antiviral coatings and textiles, which can be utilised in the production of personal protective equipment, has the p …
Optical Nanobubble Amplification Enables Compartment- and Enzyme-Free Digital Attomolar Protein Absolute Quantification.
Zhang T, Gao Y, Liu Y, Zhang Y, Huynh H, Chen J, Xie C, Ye H, Ge X, Kahn JS, Qin Z. Zhang T, et al. Nano Lett. 2025 Nov 19;25(46):16443-16450. doi: 10.1021/acs.nanolett.5c04401. Epub 2025 Nov 6. Nano Lett. 2025. PMID: 41198576
Using BEACON, we achieved attomolar detection limits for clinically relevant protein biomarkers: PSA (32 aM), COVID-S (123 aM), and RSV fusion (65 aM). BEACON offers a simplified, rapid, and highly sensitive alternative to existing digital immunoassays with significant pot …
Using BEACON, we achieved attomolar detection limits for clinically relevant protein biomarkers: PSA (32 aM), COVID-S (123 aM), and R …
Enhancing Athlete Resilience: Preliminary Validation of the Sports Mind Inventory and the Impact of Yoga of Immortals on Sports-Related Stress.
Shivanand I, Dewan N, Kathuria H, Verma S. Shivanand I, et al. Behav Sci (Basel). 2025 Oct 12;15(10):1385. doi: 10.3390/bs15101385. Behav Sci (Basel). 2025. PMID: 41153175 Free PMC article.
Further, there were minimal tools available to measure Sports resilience, specifically during COVID-19 restrictions or earlier. This study reports the preliminary validation of the Sports Mind Inventory (SMI) in athletes from different geographical areas (n = 66), w …
Further, there were minimal tools available to measure Sports resilience, specifically during COVID-19 restrictions or earlier …
Superhydrophilic Silica-Coated Au Nanoislands for Efficient Capture and Enhanced SERS Detection of Airborne Biomarkers.
Lee S, Park J, Han S, Yu ES, Kim J, Hwang CSH, Lee DS, Jeong KH. Lee S, et al. ACS Appl Mater Interfaces. 2025 Nov 5;17(44):60269-60277. doi: 10.1021/acsami.5c16035. Epub 2025 Oct 27. ACS Appl Mater Interfaces. 2025. PMID: 41143394
The combined effects result in a 1.95 increase in the SERS peak signal intensity, allowing nanomolar detection of acetic acid, adenosine, IL-6, EGFR, and the SARS-CoV-2 spike protein. The scAuNIs can serve as a breath biopsy platform for identifying diverse b …
The combined effects result in a 1.95 increase in the SERS peak signal intensity, allowing nanomolar detection of acetic acid, adenosine, IL …
Molecular Dynamics Simulations of the Spike Protein Receptor Binding Domain Adsorption to Material Surfaces.
Farouq MAH, Kubiak-Ossowska K, Al-Qaraghuli MM, Ferro VA, Mulheran PA. Farouq MAH, et al. J Phys Chem B. 2025 Nov 6;129(44):11421-11429. doi: 10.1021/acs.jpcb.5c04391. Epub 2025 Oct 22. J Phys Chem B. 2025. PMID: 41124382 Free PMC article.
The receptor binding domain (RBD) of the SARS-CoV-2 spike protein is an important diagnostic and therapeutic target since it binds to the peptidase domain of the angiotensin-converting enzyme 2 (ACE2) receptor, thus facilitating infection by the virus. ...
The receptor binding domain (RBD) of the SARS-CoV-2 spike protein is an important diagnostic and therapeutic target sin …
Exploration of the Tolerance of Novel Coronaviruses to Temperature Changes Based on SERS Technology.
Peng Y, Zhao S, Tanemura M, Yang Y, Liu M. Peng Y, et al. Biosensors (Basel). 2025 Aug 22;15(9):558. doi: 10.3390/bios15090558. Biosensors (Basel). 2025. PMID: 41002298 Free PMC article.
With the synergistic contribution of the "lightning rod" effect and the enhanced coupling surface plasmon caused by the nanoarrays, the ultra-sensitive detection of SARS-CoV-2 S protein with a concentration of 1 pg/mL and SERS enhancement factor of 4.89 10(9) …
With the synergistic contribution of the "lightning rod" effect and the enhanced coupling surface plasmon caused by the nanoarrays, the ultr …
Hybrid Silver-Silica and Organic Biocide Systems in PVC: Enhanced Antiviral Performance against SARS-CoV-2.
da Silva DJ, Gramcianinov GB, Malaquias VB, Jorge PZ, Gonsales C, Pereira EWA, Amurin LG, Hiroyuki Hirata M, Augusto CC, Batista BL, Alves BB, Bueno LA, Carastan DJ, Champeau M. da Silva DJ, et al. ACS Appl Mater Interfaces. 2025 Oct 8;17(40):56439-56453. doi: 10.1021/acsami.5c12270. Epub 2025 Sep 24. ACS Appl Mater Interfaces. 2025. PMID: 40990377 Free PMC article.
Poly(vinyl chloride) (PVC) is widely used in biomedical devices and hospital infrastructure. In light of emerging pathogens such as SARS-CoV-2, there is a growing need for PVC materials with intrinsic antiviral properties. ...Whereas a concentration of 2.5 wt …
Poly(vinyl chloride) (PVC) is widely used in biomedical devices and hospital infrastructure. In light of emerging pathogens such as SARS …
Retifanlimab versus placebo in combination with platinum-based chemotherapy in patients with first-line non-squamous or squamous metastatic non-small-cell lung cancer (POD1UM-304): a phase 3, multiregional, placebo-controlled, double-blind, randomised study.
Lu S, Vynnychenko O, Kulyaba Y, Kuchava V, Ibrahim A, Moiseenko F, Arslan C, Nguyen DT, Petrovic M, Cicin I, Bibichadze K, Cil T, Shi J, Olmez OF, Gogishvili M, Artac M, Nguyen HG, Cornfeld M, Tian C, Munteanu MC, Sette CVM, Bondarenko I; POD1UM-304 Study Team. Lu S, et al. Lancet Respir Med. 2025 Dec;13(12):1096-1107. doi: 10.1016/S2213-2600(25)00209-7. Epub 2025 Sep 19. Lancet Respir Med. 2025. PMID: 40983066 Clinical Trial.
Overall, higher incidences of treatment-emergent adverse events that were serious (158 [41%] of 389 vs 57 [30%] of 190), grade 3 or worse (238 [61%] vs 103 [54%]), or led to retifanlimab or placebo dose delay (169 [43%] vs 67 [35%]) or discontinuation (33 [8%] vs nine [5%]) were …
Overall, higher incidences of treatment-emergent adverse events that were serious (158 [41%] of 389 vs 57 [30%] of 190), grade 3 or worse (2 …
253 results