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Page 1
Validation of the US Food and Drug Administration's COVID-19 Disease Severity Categorization for Use in Real-World Data.
Perez-Vilar S, Hua W, Kwist A, Ma Y, Dong D, Zhang R, Ma Y, Chavez A, Huang N, Sheikh V, Chiang Y, Salone C, Pica N, Zhu Y, Pratt N, Nadimpalli G, Pershing S, Wernecke M, Cunningham FE, Graham DJ. Perez-Vilar S, et al. Pharmacoepidemiol Drug Saf. 2025 Nov;34(11):e70252. doi: 10.1002/pds.70252. Pharmacoepidemiol Drug Saf. 2025. PMID: 41208338
RESULTS: We received medical records for 190 (77%) beneficiaries. Of these, 171 had a positive SARS-CoV-2 test result. The PPV of the COVID-19 diagnosis code was 89% (CI: 83%-93%) overall, 88% (CI: 80%-93%) in the ambulatory setting, and 93% (CI …
RESULTS: We received medical records for 190 (77%) beneficiaries. Of these, 171 had a positive SARS-CoV-2 test result. …
Knowledge, attitudes and practices related to SARS-CoV-2 prevention in Kenya.
Cebula BR, Ying R, Hamby T, Tonzel J, Kosgei J, Langat D, Bor R, Gayle B, Romo ML, Schluck G, Akoth C, Sawe F, Yacovone M, Ake JA, Crowell TA. Cebula BR, et al. J Public Health Afr. 2025 Oct 23;16(1):1401. doi: 10.4102/jphia.v16i1.1401. eCollection 2025. J Public Health Afr. 2025. PMID: 41200519 Free PMC article.
BACKGROUND: Knowledge, attitudes, and practices (KAPs) regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-pharmaceutical interventions (NPIs) may differ among populations with health vulnerabilities. AIM: To examine COVID-19 …
BACKGROUND: Knowledge, attitudes, and practices (KAPs) regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV- …
Evolving Standards: Good Clinical Practice Insights from US FDA, MHRA UK, and Health Canada.
Grandinetti C, Budwal-Jagait M, Abid H, Gebbia E, Boley E, Williams L, Fisher A, Marcus L, Muldowney L, Sellers J, Wakelin-Smith J, Ayalew K. Grandinetti C, et al. Clin Pharmacol Ther. 2025 Nov 5:10.1002/cpt.70120. doi: 10.1002/cpt.70120. Online ahead of print. Clin Pharmacol Ther. 2025. PMID: 41194530 Free PMC article. Review.
Additionally, this article addresses the impact of the COVID-19 pandemic in accelerating trial innovations, such as the use of decentralized trial elements and digital health technologies (DHTs), while also emphasizing the need for regulatory flexibility to accelera …
Additionally, this article addresses the impact of the COVID-19 pandemic in accelerating trial innovations, such as the use of …
COVID-19 and Influenza Incidence among Active Component United States Military Service Members at Installations in US-Mexico Border States (2020-2023).
Gallaway MS, Russell DA, Hetrich MK, Hu Z, Eick-Cost AA. Gallaway MS, et al. Am J Trop Med Hyg. 2025 Nov 4:tpmd250483. doi: 10.4269/ajtmh.25-0483. Online ahead of print. Am J Trop Med Hyg. 2025. PMID: 41187337
A retrospective cohort study was conducted to assess diagnoses of influenza (2020-2024) and COVID-19 (2020-2023). Incidence rate ratios (IRRs) comparing influenza and COVID-19 at border and non-border locations were calculated for laboratory-confirmed …
A retrospective cohort study was conducted to assess diagnoses of influenza (2020-2024) and COVID-19 (2020-2023). Incidence ra …
International Collaboration to Develop and Harmonize Drug Interaction Guidance for Nirmatrelvir/Ritonavir During COVID-19: Lessons Learned for Future Pandemic Preparedness.
Kuriakose S, Tseng A, Boyd S, Gibbons S, Chiong J, Marra F, Boyle A, Senneker T, George J, Lund C, Belperio P, Crew P, Eschenauer G, Scarsi KK, Khoo SH, Pau A, Marzolini C; LiON-PK collaboration. Kuriakose S, et al. Clin Infect Dis. 2025 Nov 3:ciaf606. doi: 10.1093/cid/ciaf606. Online ahead of print. Clin Infect Dis. 2025. PMID: 41178257
In December 2021/January 2022, the SARS-CoV-2 antiviral drug, nirmatrelvir/ritonavir, was authorized in the United States, Canada, and Europe. ...To support clinicians, the National Institutes of Health COVID-19 Guidelines Panel, the Ontario Sci …
In December 2021/January 2022, the SARS-CoV-2 antiviral drug, nirmatrelvir/ritonavir, was authorized in the United Stat …
A split GFP approach to assay SARS-CoV-2 spike-dependent cell fusion.
Morwitzer MJ, Zheng YY, Friberg H, Currier JR. Morwitzer MJ, et al. J Virol Methods. 2025 Nov 1;340:115296. doi: 10.1016/j.jviromet.2025.115296. Online ahead of print. J Virol Methods. 2025. PMID: 41177465
The SARS-CoV-2 spike (S) protein plays a central role in viral entry through receptor binding and membrane fusion, making it a key target for therapeutic interventions. ...By enabling the quantitative, real-time assessment of spike-mediated fusion, this platf …
The SARS-CoV-2 spike (S) protein plays a central role in viral entry through receptor binding and membrane fusion, maki …
The interplay between gamma delta (γδ) T cells and cellular stress pathways in the pathogenesis of emerging human viral zoonoses.
Dutta S, Ganguly A, Ghosh Roy S. Dutta S, et al. Int Rev Cell Mol Biol. 2025;398:99-149. doi: 10.1016/bs.ircmb.2025.08.011. Epub 2025 Sep 11. Int Rev Cell Mol Biol. 2025. PMID: 41161894 Review.
This chapter examines the activation mechanisms of gammadelta T cells in response to viral infectious agents such as Influenza A virus, SARS-CoV-2, West Nile Virus (WNV), Dengue virus, and Human immunodeficiency virus (HIV) emphasizing their role in pathogen …
This chapter examines the activation mechanisms of gammadelta T cells in response to viral infectious agents such as Influenza A virus, S …
Silver Thin-Film Plated Interconnected Metal Mesh Networks for Virus Detection and Prevention.
Choi TM, Lee HR, Pyo SG. Choi TM, et al. Micromachines (Basel). 2025 Oct 17;16(10):1177. doi: 10.3390/mi16101177. Micromachines (Basel). 2025. PMID: 41156423 Free PMC article.
Many viruses, bacteria, and pollen that cause diseases such as COVID-19 are inhaled by humans as aerosols. Therefore, wearing a mask to block pathogen-containing aerosols is crucial for disease prevention. ...To address this, a reusable mask incorporating the antiba …
Many viruses, bacteria, and pollen that cause diseases such as COVID-19 are inhaled by humans as aerosols. Therefore, wearing …
Multi- and Transgenerational Effects of Silver Ions (Ag(+)) in the ng/L Range on Life Cycle Parameters and Population Growth of the Midge Chironomus riparius (Diptera, Chironomidae).
Ding J, Krais S, Li Z, Triebskorn R, Köhler HR. Ding J, et al. Toxics. 2025 Oct 10;13(10):855. doi: 10.3390/toxics13100855. Toxics. 2025. PMID: 41150554 Free PMC article.
Silver (Ag) is widely released into aquatic environments through industrial and municipal discharges, with concentrations often reaching toxic levels for aquatic organisms. Its further extensive use in antimicrobials, especially during the COVID-19 pandemic, …
Silver (Ag) is widely released into aquatic environments through industrial and municipal discharges, with concentrations often reach …
2,068 results