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2020 28
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2026 10

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301 results

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Page 1
Identification of metabolic signatures of immune response following mRNA and inactivated vaccines against COVID-19: a systematic review.
Wasilewski A, Serrafi A. Wasilewski A, et al. Front Immunol. 2026 Feb 25;17:1783878. doi: 10.3389/fimmu.2026.1783878. eCollection 2026. Front Immunol. 2026. PMID: 41822480 Free PMC article. Review.
BACKGROUND: Metabolomic profiling offers insights into immune responses, yet a synthesis of systemic metabolic changes after COVID-19 vaccination is lacking. This review aims to characterize vaccination-induced metabolomic alterations and identify correlative biomar …
BACKGROUND: Metabolomic profiling offers insights into immune responses, yet a synthesis of systemic metabolic changes after COVID- …
Tryptophan metabolism reprogramming potentially contributes to the prothrombotic milieu in mice and humans with SARS-CoV-2.
Subramaniam S, Napoleon MA, Lotfollahzadeh S, Kamal MH, Kurniawan H, Francis C, Elsadawi M, Wu Wong DJ, Kenney D, Douam F, Bosmann M, Whelan SA, Cabral H, Burks EJ, Zhao G, Kolachalama VB, Ravid K, Chitalia VC. Subramaniam S, et al. Blood Vessel Thromb Hemost. 2026 Jan 5;3(1):100128. doi: 10.1016/j.bvth.2025.100128. eCollection 2026 Feb. Blood Vessel Thromb Hemost. 2026. PMID: 41743170 Free PMC article.
The role of prothrombotic metabolites in COVID-19-associated coagulopathy remains elusive. Leveraging K18-hACE2 mice infected with SARS-CoV-2, we observed higher levels of the tryptophan metabolite, kynurenine, than in controls. ...Kynure …
The role of prothrombotic metabolites in COVID-19-associated coagulopathy remains elusive. Leveraging K18-hACE2 mice infected …
Microbiome-Metabolome Crosstalk as a Driver of COVID-19 Severity.
Diez-Echave P, Rodríguez-Sojo MJ, Martin-Castaño B, Hidalgo-García L, Ruiz-Malagon AJ, Molina-Tijeras JA, Romero AR, Martínez-Zaldívar M, Mota E, Cobo F, Alvarez-Estevez M, García F, Morales-García C, Merlos S, García-Flores P, Colmenero-Ruiz M, Nuñez M, Ruiz-Sancho A, Rodríguez-Cabezas ME, Gallego ÁC, Fernandez-Varón E, Pérez Del Palacio J, Martin J, García-García J, Morón R, Rodríguez-Nogales A, Gálvez J. Diez-Echave P, et al. Med Sci (Basel). 2026 Feb 17;14(1):97. doi: 10.3390/medsci14010097. Med Sci (Basel). 2026. PMID: 41718144 Free PMC article.
Background: COVID-19, caused by SARS-CoV-2, exhibits highly variable severity, from mild symptoms to respiratory failure and multiorgan dysfunction. ...Methods: Thus, this study investigates how gut microbiota variations are associated with plas …
Background: COVID-19, caused by SARS-CoV-2, exhibits highly variable severity, from mild symptoms to resp …
COVID-19 Impact on Lipid Profile and Metabolome in Patients with Type 2 Diabetes Mellitus: Mini-Review.
Pawłuszkiewicz K, Faltus AM, Augustynowicz G, Bielenin Z, Bronowicka-Szydełko A, Madziarska K, Paluch E, Porębska B, Kluz J. Pawłuszkiewicz K, et al. Curr Diabetes Rev. 2026 Feb 13. doi: 10.2174/0115733998404775251202121401. Online ahead of print. Curr Diabetes Rev. 2026. PMID: 41691687
AIM: This review aims to explore the pathophysiological mechanisms by which SARS-- CoV-2 affects lipid metabolism and the metabolome in patients with Type 2 Diabetes Mellitus (T2DM). ...Search terms included: (Post-COVID-19) AND (Diabetes Mellit …
AIM: This review aims to explore the pathophysiological mechanisms by which SARS-- CoV-2 affects lipid metabolism and t …
Quinolinic acid as trigger/biomarker of dysosmia/dysgeusia in patients with acute coronavirus disease 2019: A retrospective case-control study.
Tsukiji J, Koizume S, Takahashi T, Murakami S, Takahashi H, Mitsunaga S, Nakamura S, Narimatsu H, Miyagi Y. Tsukiji J, et al. Brain Behav Immun Health. 2026 Jan 12;52:101175. doi: 10.1016/j.bbih.2026.101175. eCollection 2026 Mar. Brain Behav Immun Health. 2026. PMID: 41630806 Free PMC article.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can activate Trp metabolism. Therefore, we investigated whether serum metabolites of Trp and IDO/TDO activity could serve as biomarkers for assessing smell/taste impairment (dysosmia/dysgeusi …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can activate Trp metabolism. Therefore, we investig …
Conformational Heterogeneity and Redox Switching of the Cysteine Residues in SARS-CoV-2 Main Protease: A Raman Molecular Fingerprint.
Nanda B, Maity A, Nandi RP, Dolui S, Misra R, Pal U, Maiti NC. Nanda B, et al. J Phys Chem B. 2026 Feb 12;130(6):1755-1773. doi: 10.1021/acs.jpcb.5c06195. Epub 2026 Feb 2. J Phys Chem B. 2026. PMID: 41622872
The main protease (Mpro/3CLpro) of the SARS-CoV-2 virus activates the viral nonstructural proteins (nsp) into functional units inside the host cells and kickstarts the viral replication-translation machinery, acting as a central molecular switch. ...Raman spe …
The main protease (Mpro/3CLpro) of the SARS-CoV-2 virus activates the viral nonstructural proteins (nsp) into functiona …
The Interaction Between Orientin and the Spike of SARS-CoV-2: An In Silico and Experimental Approach.
Pacheco GC, Ribeiro MS, de Magalhães CS, Carneiro FA. Pacheco GC, et al. Viruses. 2025 Dec 31;18(1):61. doi: 10.3390/v18010061. Viruses. 2025. PMID: 41600826 Free PMC article.
SARS-CoV-2, the causative agent of COVID-19, has led to over seven million deaths worldwide prior to May 2025. Despite widespread vaccination programs, COVID-19 remains a persistent global health challenge, underscoring the urgent …
SARS-CoV-2, the causative agent of COVID-19, has led to over seven million deaths worldwide prior to May …
Engineering an abiotic antibody mimic: Structural and molecular mechanisms for targeting, neutralizing, and point-of-care testing virus antigens.
Tang W, Wan Z, Cheng Q, Li B, Qiu Y, Chen Y, Lin S, Tan W, Jin H, Liu M. Tang W, et al. Talanta. 2026 May 1;301:129324. doi: 10.1016/j.talanta.2025.129324. Epub 2025 Dec 28. Talanta. 2026. PMID: 41478048
Herein, we engineer an abiotic antibody mimic, a hydrogel polymer nanoparticle (NP), for targeting the SARS-CoV-2 spike antigen and, based on this, construct a core-shell nanoprobe by in situ polymerization on AuNPs for precise antigen/pseudovirus recognition …
Herein, we engineer an abiotic antibody mimic, a hydrogel polymer nanoparticle (NP), for targeting the SARS-CoV-2 spike …
Characterizing Origin of Differences in Chemical Composition, Rumen Degradability, Intestinal Digestibility and Amino Acid Profile of Traditional Beer Brewing Byproducts.
Tadesse A, De Neve N, Tesfay Y, Vermeir P, De Meulenaer B, Fievez V. Tadesse A, et al. Food Sci Nutr. 2025 Dec 30;14(1):e71380. doi: 10.1002/fsn3.71380. eCollection 2026 Jan. Food Sci Nutr. 2025. PMID: 41476711 Free PMC article.
Cereal type-dependent variations were observed (p < 0.05) in rumen degradation of DM, CP and AA, except for tryptophan. Heat treatment did not influence the ruminal degradation of DM, CP and AA, except for valine. ...

Cereal type-dependent variations were observed (p < 0.05) in rumen degradation of DM, CP and AA, except for tryptophan. Heat treat

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Spike protein-induced VSIR-ISX signaling disrupts metabolic homeostasis and promotes COVID-19-related immune dysfunction.
Wang LT, Wang SN, Chiou SS, Chai CY, Hsu SH. Wang LT, et al. Cell Biol Toxicol. 2025 Dec 19;42(1):2. doi: 10.1007/s10565-025-10119-2. Cell Biol Toxicol. 2025. PMID: 41417109 Free PMC article.
COVID-19 has caused millions of deaths worldwide since 2019. Vaccination has reduced both transmission and disease severity. ...Our findings suggest that the VSIR-ISX pathway could be a promising therapeutic target for treating COVID-19 by addressing v …
COVID-19 has caused millions of deaths worldwide since 2019. Vaccination has reduced both transmission and disease severity. . …
301 results