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Lactoferrin, a Natural Protein with Multiple Functions in Health and Disease.
Rizzi M, Manzoni P, Germano C, Quevedo MF, Sainaghi PP. Rizzi M, et al. Nutrients. 2025 Oct 29;17(21):3403. doi: 10.3390/nu17213403. Nutrients. 2025. PMID: 41228476 Free PMC article. Review.
Thanks to these biological properties, lactoferrin has widely been studied as a therapeutic agent in gastroenteric diseases, neonatal sepsis and necrotizing enterocolitis, lung diseases, and COVID-19, showing very heterogeneous results based on the disease considere …
Thanks to these biological properties, lactoferrin has widely been studied as a therapeutic agent in gastroenteric diseases, neonatal sepsis …
Lactoferrin and SIgA Concentrations in Human Milk of SARS-CoV-Infected Mothers-Polish Cohort Study.
Mołas A, Lis-Kuberka J, Bzikowska-Jura A, Wesołowska A, Jin T, Socha MW, Orczyk-Pawiłowicz M. Mołas A, et al. Nutrients. 2025 May 28;17(11):1840. doi: 10.3390/nu17111840. Nutrients. 2025. PMID: 40507109 Free PMC article.
Results: The presence of specific anti-SARS-CoV-2 SIgA antibodies was assessed via cassette serological lateral flow detection tests. ...Furthermore, 75% of infected mothers had positive anti-SARS-CoV-2 SIgA results. These mothers also sh …
Results: The presence of specific anti-SARS-CoV-2 SIgA antibodies was assessed via cassette serological lateral flow de …
Effect of combined training on the cardiorespiratory, muscle system and body composition in employees at a tertiary hospital after mild to moderate intensity COVID 19.
Grecco MV, Moura Dos Santos A, Greve JD, Alonso AC, Afonso MS, de Sousa JC, Quintana MSL, Soares-Junior JM, Baracat EC, Brech GC, Silva PRS. Grecco MV, et al. Clinics (Sao Paulo). 2025 Apr 25;80:100614. doi: 10.1016/j.clinsp.2025.100614. eCollection 2025. Clinics (Sao Paulo). 2025. PMID: 40286728 Free PMC article.
OBJECTIVE: To verify the effect of 12 weeks of Combined Training (CT) in patients suffering from COVID-19 of mild to moderate intensity. METHODS: 69 participants diagnosed with mild to moderate COVID-19 were evaluated, with shortness of breath as the m …
OBJECTIVE: To verify the effect of 12 weeks of Combined Training (CT) in patients suffering from COVID-19 of mild to moderate …
Diet, microbiome, and probiotics establish a crucial link in vaccine efficacy.
Dutta S, Chatterjee N, Gallina NLF, Kar S, Koley H, Nanda PK, Biswas O, Das AK, Biswas S, Bhunia AK, Dhar P. Dutta S, et al. Crit Rev Microbiol. 2025 Nov;51(6):1127-1152. doi: 10.1080/1040841X.2025.2480230. Epub 2025 Mar 20. Crit Rev Microbiol. 2025. PMID: 40110742 Free article. Review.
Unveiling this link is imperative, particularly in the post-pandemic world, considering impaired COVID-19 vaccine response observed in dysbiotic individuals. Therefore, this article aims to comprehensively review how diet and probiotics can modulate gut microbiome c …
Unveiling this link is imperative, particularly in the post-pandemic world, considering impaired COVID-19 vaccine response obs …
Effects of different sources of lactoferrin on cytokine response to SARS-COV-2, respiratory syncytial virus, and rotavirus infection in vitro.
Jiang R, Du X, Lönnerdal B. Jiang R, et al. Biochem Cell Biol. 2025 Jan 1;103:1-12. doi: 10.1139/bcb-2024-0146. Biochem Cell Biol. 2025. PMID: 40085927
Here, effects of Lfs (11 commercial bovine milk Lfs, 2 recombinant Lfs, and native human/bovine milk Lf) on cytokine responses to virus infection were examined by infecting human intestinal epithelial cells (Caco-2 cells) with rotavirus (naked) or normal human bronchial epithelia …
Here, effects of Lfs (11 commercial bovine milk Lfs, 2 recombinant Lfs, and native human/bovine milk Lf) on cytokine responses to virus infe …
A comprehensive review of research advances in the study of lactoferrin to treat viral infections.
Shafqat A, Li M, Zakirullah, Liu F, Tong Y, Fan J, Fan H. Shafqat A, et al. Life Sci. 2025 Jan 15;361:123340. doi: 10.1016/j.lfs.2024.123340. Epub 2024 Dec 25. Life Sci. 2025. PMID: 39730037 Review.
Numerous studies have demonstrated its antiviral effectiveness against multiple viruses, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza virus (IFV), herpes simplex virus (HSV), hepatitis B virus (HBV), and human immunod …
Numerous studies have demonstrated its antiviral effectiveness against multiple viruses, such as severe acute respiratory syndrome coronavir …
The potential of lactoferrin as antiviral and immune-modulating agent in viral infectious diseases.
Eker F, Duman H, Ertürk M, Karav S. Eker F, et al. Front Immunol. 2024 Nov 15;15:1402135. doi: 10.3389/fimmu.2024.1402135. eCollection 2024. Front Immunol. 2024. PMID: 39620218 Free PMC article. Review.
Herein we summarize studies in which this competition was investigated with SARS-CoV-2, Zika, Dengue, Hepatitis and Influenza viruses in vitro. These studies have demonstrated not only Lf's competitive properties, but also its potential intracellular impact o …
Herein we summarize studies in which this competition was investigated with SARS-CoV-2, Zika, Dengue, Hepatitis and Inf …
Immunomodulatory effect of bovine lactoferrin during SARS-CoV-2 infection.
da Silva AMV, Machado TL, Nascimento RS, Rodrigues MPMD, Coelho FS, Tubarão LN, da Rosa LC, Bayma C, Rocha VP, Frederico ABT, Silva J, Cunha DRABE, de Souza AF, de Souza RBG, Barros CA, Fiscina DDS, Ribeiro LCP, de Carvalho CAM, da Silva BJD, Muller R, Azamor T, Melgaço JG, Gonçalves RB, Ano Bom APD. da Silva AMV, et al. Front Immunol. 2024 Oct 17;15:1456634. doi: 10.3389/fimmu.2024.1456634. eCollection 2024. Front Immunol. 2024. PMID: 39483459 Free PMC article.
INTRODUCTION: Lactoferrin (Lf) is an important immunomodulator in infections caused by different agents. During SARS-CoV-2 infection, Lf can hinder or prevent virus access to the intracellular environment. Severe cases of COVID-19 are related to …
INTRODUCTION: Lactoferrin (Lf) is an important immunomodulator in infections caused by different agents. During SARS-CoV-2 …
Lactoferrin Supplementation in Preventing and Protecting from SARS-CoV-2 Infection: Is There Any Role in General and Special Populations? An Updated Review of Literature.
Manzoni P, Messina A, Germano C, Picone S, Masturzo B, Sainaghi PP, Sola D, Rizzi M. Manzoni P, et al. Int J Mol Sci. 2024 Sep 24;25(19):10248. doi: 10.3390/ijms251910248. Int J Mol Sci. 2024. PMID: 39408576 Free PMC article. Review.
At the beginning of the pandemic, SARS-CoV-2 infection represented a great medical burden worldwide, as targeted and effective therapeutic options were lacking. ...Among the latter, lactoferrin has been investigated as an adjuvant in COVID-19 th …
At the beginning of the pandemic, SARS-CoV-2 infection represented a great medical burden worldwide, as targeted and ef …
Assessment of Supplementation with Different Biomolecules in the Prevention and Treatment of COVID-19.
González-Acedo A, Manzano-Moreno FJ, García-Recio E, Ruiz C, Luna-Bertos E, Costela-Ruiz VJ. González-Acedo A, et al. Nutrients. 2024 Sep 11;16(18):3070. doi: 10.3390/nu16183070. Nutrients. 2024. PMID: 39339670 Free PMC article. Review.
Consequences of the disease produced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have led to an urgent search for preventive and therapeutic strategies. ...The objective of this study was to review published evidence on the clin …
Consequences of the disease produced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have le …
89 results