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A comprehensive review of research advances in the study of lactoferrin to treat viral infections.
Shafqat A, Li M, Zakirullah, Liu F, Tong Y, Fan J, Fan H. Shafqat A, et al. Life Sci. 2025 Jan 15;361:123340. doi: 10.1016/j.lfs.2024.123340. Epub 2024 Dec 25. Life Sci. 2025. PMID: 39730037 Review.
Numerous studies have demonstrated its antiviral effectiveness against multiple viruses, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza virus (IFV), herpes simplex virus (HSV), hepatitis B virus (HBV), and human immunodeficien …
Numerous studies have demonstrated its antiviral effectiveness against multiple viruses, such as severe acute respiratory syndrome coronavir …
The potential of lactoferrin as antiviral and immune-modulating agent in viral infectious diseases.
Eker F, Duman H, Ertürk M, Karav S. Eker F, et al. Front Immunol. 2024 Nov 15;15:1402135. doi: 10.3389/fimmu.2024.1402135. eCollection 2024. Front Immunol. 2024. PMID: 39620218 Free PMC article. Review.
Herein we summarize studies in which this competition was investigated with SARS-CoV-2, Zika, Dengue, Hepatitis and Influenza viruses in vitro. These studies have demonstrated not only Lf's competitive properties, but also its potential intracellular impact o …
Herein we summarize studies in which this competition was investigated with SARS-CoV-2, Zika, Dengue, Hepatitis and Inf …
Immunomodulatory effect of bovine lactoferrin during SARS-CoV-2 infection.
da Silva AMV, Machado TL, Nascimento RS, Rodrigues MPMD, Coelho FS, Tubarão LN, da Rosa LC, Bayma C, Rocha VP, Frederico ABT, Silva J, Cunha DRABE, de Souza AF, de Souza RBG, Barros CA, Fiscina DDS, Ribeiro LCP, de Carvalho CAM, da Silva BJD, Muller R, Azamor T, Melgaço JG, Gonçalves RB, Ano Bom APD. da Silva AMV, et al. Front Immunol. 2024 Oct 17;15:1456634. doi: 10.3389/fimmu.2024.1456634. eCollection 2024. Front Immunol. 2024. PMID: 39483459 Free PMC article.
INTRODUCTION: Lactoferrin (Lf) is an important immunomodulator in infections caused by different agents. During SARS-CoV-2 infection, Lf can hinder or prevent virus access to the intracellular environment. Severe cases of COVID-19 are related to …
INTRODUCTION: Lactoferrin (Lf) is an important immunomodulator in infections caused by different agents. During SARS-CoV-2 …
Lactoferrin Supplementation in Preventing and Protecting from SARS-CoV-2 Infection: Is There Any Role in General and Special Populations? An Updated Review of Literature.
Manzoni P, Messina A, Germano C, Picone S, Masturzo B, Sainaghi PP, Sola D, Rizzi M. Manzoni P, et al. Int J Mol Sci. 2024 Sep 24;25(19):10248. doi: 10.3390/ijms251910248. Int J Mol Sci. 2024. PMID: 39408576 Free PMC article. Review.
At the beginning of the pandemic, SARS-CoV-2 infection represented a great medical burden worldwide, as targeted and effective therapeutic options were lacking. ...Among the latter, lactoferrin has been investigated as an adjuvant in COVID-19 th …
At the beginning of the pandemic, SARS-CoV-2 infection represented a great medical burden worldwide, as targeted and ef …
Assessment of Supplementation with Different Biomolecules in the Prevention and Treatment of COVID-19.
González-Acedo A, Manzano-Moreno FJ, García-Recio E, Ruiz C, Luna-Bertos E, Costela-Ruiz VJ. González-Acedo A, et al. Nutrients. 2024 Sep 11;16(18):3070. doi: 10.3390/nu16183070. Nutrients. 2024. PMID: 39339670 Free PMC article. Review.
The objective of this study was to review published evidence on the clinical usefulness of supplementation with vitamin D, antioxidant vitamins (vitamin A, vitamin E, and vitamin C), melatonin, lactoferrin and natural products found in food (curcumin, luteolin, ginger, allicin, m …
The objective of this study was to review published evidence on the clinical usefulness of supplementation with vitamin D, antioxidant vitam …
MFGM-enriched whey displays antiviral activity against common pediatric viruses in vitro.
Kramer E, Patil K, Triantis V, Bastiaans JAH, Mazzon M, Ramani S, Lambers TT. Kramer E, et al. Front Nutr. 2024 Jul 31;11:1416352. doi: 10.3389/fnut.2024.1416352. eCollection 2024. Front Nutr. 2024. PMID: 39149543 Free PMC article.
More recently, a similar activity of milk derived proteins was suggested for SARS-CoV-2. The goal of the current study was to test antiviral activity of the bovine milkfat globule membrane (MFGM) against rotavirus, RSV and SARS-CoV-2 …
More recently, a similar activity of milk derived proteins was suggested for SARS-CoV-2. The goal of the current …
Impact of COVID-19 vaccination on saliva immune barriers: IgA, lysozyme, and lactoferrin.
Abdul-Kareem HH, Al-Maqtoofi MY, Burghal AA. Abdul-Kareem HH, et al. Arch Virol. 2023 Nov 16;168(12):293. doi: 10.1007/s00705-023-05914-3. Arch Virol. 2023. PMID: 37973637 Review.
Understanding the role of salivary constituents, such as lactoferrin, lysozyme, and secretory immunoglobulin A (sIgA), in immune protection and defense mechanisms against microbial invasion and colonization of the airways is important in light of the ongoing severe acute respirat …
Understanding the role of salivary constituents, such as lactoferrin, lysozyme, and secretory immunoglobulin A (sIgA), in immune protection …
Sigma Receptor Ligands Prevent COVID Mortality In Vivo: Implications for Future Therapeutics.
Berkowitz RL, Bluhm AP, Knox GW, McCurdy CR, Ostrov DA, Norris MH. Berkowitz RL, et al. Int J Mol Sci. 2023 Oct 29;24(21):15718. doi: 10.3390/ijms242115718. Int J Mol Sci. 2023. PMID: 37958703 Free PMC article.
Furthermore, lactoferrin, a well-characterized immunomodulatory protein, has shown antiviral efficacy against SARS-CoV-2 both in laboratory settings and in living organisms. ...Mice treated with sigma-2 receptor ligands or diphenhydramine and lactoferr …
Furthermore, lactoferrin, a well-characterized immunomodulatory protein, has shown antiviral efficacy against SARS-CoV- …
A Mediterranean-Style Diet Improves the Parameters for the Management and Prevention of Type 2 Diabetes Mellitus.
Derrick SA, Nguyen ST, Marthens JR, Dambacher LL, Sikalidis AK, Reaves SK. Derrick SA, et al. Medicina (Kaunas). 2023 Oct 23;59(10):1882. doi: 10.3390/medicina59101882. Medicina (Kaunas). 2023. PMID: 37893600 Free PMC article.
This study's protocol included following a Mediterranean-style diet, the daily consumption of a high-quality whey protein supplement, and physical activity recommendations for 16 weeks. Body composition data, via dual-energy X-ray absorptiometry (DXA), and fasting b …
This study's protocol included following a Mediterranean-style diet, the daily consumption of a high-quality whey protein supp …
Milk Casein Inhibits Effect of Black Tea Galloylated Theaflavins to Inactivate SARS-CoV-2 In Vitro.
Nakashio M, Ohgitani E, Shin-Ya M, Kawamoto M, Ichitani M, Kobayashi M, Takihara T, Kinugasa H, Ishikura H, Mazda O. Nakashio M, et al. Bioengineering (Basel). 2023 Sep 9;10(9):1068. doi: 10.3390/bioengineering10091068. Bioengineering (Basel). 2023. PMID: 37760169 Free PMC article.
Continuing caution is required against the potential emergence of SARS-CoV-2 novel mutants that could pose the next global health and socioeconomical threats. ...The present study demonstrates for the first time that an addition of milk cancelled the anti- …
Continuing caution is required against the potential emergence of SARS-CoV-2 novel mutants that could pose the next glo …
84 results