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Associations of body weight and COVID-19 with autoimmunity in pediatric new-onset type 1 diabetes: results from the prospective DPV registry.
Boettcher C, Holl R, Nagl K, Karges B, Von Sengbusch S, Welters A, Warncke K, Flury M, Nahdiyati D, von dem Berge T, Kamrath C. Boettcher C, et al. BMJ Open Diabetes Res Care. 2026 Jan 16;14(1):e005349. doi: 10.1136/bmjdrc-2025-005349. BMJ Open Diabetes Res Care. 2026. PMID: 41545230
INTRODUCTION: This study analyzed the effects of the COVID-19 pandemic and body weight on islet and endocrine autoimmunity in children with type 1 diabetes (T1D). ...Logistic regression models adjusted for age and sex examined associations with COVID-19 …
INTRODUCTION: This study analyzed the effects of the COVID-19 pandemic and body weight on islet and endocrine autoimmunity in …
Metal ions govern coronavirus endoribonuclease activity.
Wang X, Li J, Liu Z, Wang L, Zhu B. Wang X, et al. Nucleic Acids Res. 2026 Jan 14;54(2):gkaf1508. doi: 10.1093/nar/gkaf1508. Nucleic Acids Res. 2026. PMID: 41533565 Free PMC article.
In the presence of Co2+, cryo-electron microscopy structures of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nsp15/dsRNA complexes indicate higher dsRNA-binding affinity. Active-site mutation H249A weakens the effects of Co2+, Ni2+, and Zn2+ o …
In the presence of Co2+, cryo-electron microscopy structures of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 …
Comparison of the Nutritional Value of Locally Formulated Food Preparations and Standard Ready-to-Use Therapeutic Foods for the Management of Uncomplicated Severe Acute Malnutrition in Children Under Five in the Democratic Republic of the Congo.
Bosonkie M, Mudogo CN, Silverstein H, Fawole OI, Compta G, Ngbolua KT, Koba T, Mbuyi R, Bondo B, Lusamba PS, Mapatano MA. Bosonkie M, et al. Food Sci Nutr. 2025 Dec 8;13(12):e71302. doi: 10.1002/fsn3.71302. eCollection 2025 Dec. Food Sci Nutr. 2025. PMID: 41378228 Free PMC article.
Locally formulated food preparations were mostly milk- and peanut-free, often exceeding protein and lipid recommendations but deficient in vitamins (A, D, E, K, B12, folate), and critical minerals (calcium, iron, iodine, selenium, zinc). Compliance with Codex standards was …
Locally formulated food preparations were mostly milk- and peanut-free, often exceeding protein and lipid recommendations but deficient in v …
Nanotechnology in COVID-19 prevention, diagnosis, and treatment: a comprehensive review.
Dikamu M, Syraji Y, Pr J, K G, Raza A, Ezez D. Dikamu M, et al. Discov Nano. 2025 Dec 8;20(1):225. doi: 10.1186/s11671-025-04412-6. Discov Nano. 2025. PMID: 41359142 Free PMC article. Review.
The worst of the COVID-19 (coronavirus disease 2019) pandemic may be over, but its impact continues to be felt worldwide. ...Nanotechnology contributed significantly to combating COVID-19, enhancing prevention through nanofiber-enhanced masks and nanop …
The worst of the COVID-19 (coronavirus disease 2019) pandemic may be over, but its impact continues to be felt worldwide. ...N …
Therapeutic potential of zinc oxide/berberine nanoparticles in mitigating acute respiratory distress syndrome: in vivo and in silico approaches.
El-Salakawy MS, Abd-Elmoneam AA, Nofal MS, Kolaib NM, Elkashef AA, Ghareeb AZ, Ghareeb DA. El-Salakawy MS, et al. BMC Pharmacol Toxicol. 2025 Dec 1;26(1):205. doi: 10.1186/s40360-025-01036-5. BMC Pharmacol Toxicol. 2025. PMID: 41327335 Free PMC article.
BACKGROUND: Inflammation and oxidative stress strongly contribute to the pathophysiology of acute respiratory distress syndrome (ARDS), which is a life-threatening pulmonary disease. Zinc oxide/berberine nanoparticles (ZnO/Ber-NPs) have been shown to have a protective effe …
BACKGROUND: Inflammation and oxidative stress strongly contribute to the pathophysiology of acute respiratory distress syndrome (ARDS), whic …
A Predictive Model for the Development of Long COVID in Children.
Perestiuk V, Sverstyuk A, Kosovska T, Volianska L, Boyarchuk O. Perestiuk V, et al. Int J Environ Res Public Health. 2025 Nov 9;22(11):1693. doi: 10.3390/ijerph22111693. Int J Environ Res Public Health. 2025. PMID: 41302639 Free PMC article.
The aim of our study was to develop an algorithm and mathematical model to predict the risk of developing long COVID in children who have had acute SARS-CoV-2 viral infection, taking into account a wide range of demographic, clinical, and laboratory pa …
The aim of our study was to develop an algorithm and mathematical model to predict the risk of developing long COVID in children who …
Efficacy of once-daily, high-dose, oral insulin immunotherapy in children genetically at risk for type 1 diabetes (POInT): a European, randomised, placebo-controlled, primary prevention trial.
Ziegler AG, Achenbach P, Weiß A, Berner R, Casteels K, Elding Larsson H, Haupt F, Hommel A, Jacobs A, Kordonouri O, Lundgren M, Ołtarzewski M, Pfirrmann M, Snape MD, Szypowska A, Todd JA, Vatish M, von dem Berge T, Winkler C, Bonifacio E; GPPAD-POInT Study Group. Ziegler AG, et al. Lancet. 2025 Nov 29;406(10519):2564-2576. doi: 10.1016/S0140-6736(25)01726-X. Epub 2025 Nov 11. Lancet. 2025. PMID: 41237794 Free article. Clinical Trial.
Eligible infants aged 4-7 months were randomly assigned in a 1:1 ratio to receive insulin manufactured from human zinc-insulin crystals administered orally at a once-daily dose of 7.5 mg for 2 months, increasing to 22.5 mg for 2 months and 67.5 mg until age 3 years, or pla …
Eligible infants aged 4-7 months were randomly assigned in a 1:1 ratio to receive insulin manufactured from human zinc-insulin crysta …
One Enzyme, Many Faces: The Expanding Role of DPP3 in Cardiovascular and Critical Care.
Zakynthinos GE, Kokkinos NK, Tzima IG, Dimeas IE, Gialamas I, Gerostathis A, Katsarou O, Tsatsaragkou A, Kalogeras K, Oikonomou E, Siasos G. Zakynthinos GE, et al. J Clin Med. 2025 Oct 22;14(21):7459. doi: 10.3390/jcm14217459. J Clin Med. 2025. PMID: 41226854 Free PMC article. Review.
Dipeptidyl peptidase 3 (DPP3) is a zinc-dependent aminopeptidase that is found in several places and is thought to be a cytosolic enzyme that helps break down peptides. ...High levels of circulating DPP3 (cDPP3) have been linked to the causes of cardiogenic shock, septic s …
Dipeptidyl peptidase 3 (DPP3) is a zinc-dependent aminopeptidase that is found in several places and is thought to be a cytosolic enz …
Serum zinc level independently predicts need for inpatient intubation among patients hospitalized with COVID-19: A prospective observational study.
McPherson SW, van Kuijk FJ, Ramezani S, Vitale S, Amundson WH, Caraganis A, Mahan KS, Mundae R, Reilkoff RA, Chew EY, Wacker DA. McPherson SW, et al. Nutr Clin Pract. 2025 Nov 11:10.1002/ncp.70070. doi: 10.1002/ncp.70070. Online ahead of print. Nutr Clin Pract. 2025. PMID: 41219174 Free PMC article.
Serum zinc levels may play a role in modulating COVID-19 virus replication and consequently influence clinical outcomes. ...CONCLUSION: In multivariable analysis, lower serum zinc level was an independent predictor of inpatient intubation in COVID …
Serum zinc levels may play a role in modulating COVID-19 virus replication and consequently influence clinical outcomes …
1,181 results