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Year Number of Results
2020 1456
2021 1405
2022 376
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Safety, Tolerability, and Immunogenicity of COVID-19 Vaccines: A Systematic Review and Meta-Analysis.
Yuan P, Ai P, Liu Y, Ai Z, Wang Y, Cao W, Xia X, Zheng JC. Yuan P, et al. medRxiv. 2020 Nov 4:2020.11.03.20224998. doi: 10.1101/2020.11.03.20224998. Preprint. medRxiv. 2020. PMID: 33173896 Free PMC article.
We aimed to summarize reliable medical evidence by the meta-analysis of all published clinical trials that investigated the safety, tolerability, and immunogenicity of vaccine candidates against coronavirus disease 2019 (COVID-19), caused by severe
We aimed to summarize reliable medical evidence by the meta-analysis of all published clinical trials that investigated the safety, tolerabi …
Comparison of two highly-effective mRNA vaccines for COVID-19 during periods of Alpha and Delta variant prevalence.
Puranik A, Lenehan PJ, Silvert E, Niesen MJM, Corchado-Garcia J, O'Horo JC, Virk A, Swift MD, Halamka J, Badley AD, Venkatakrishnan AJ, Soundararajan V. Puranik A, et al. medRxiv. 2021 Aug 21:2021.08.06.21261707. doi: 10.1101/2021.08.06.21261707. Preprint. medRxiv. 2021. PMID: 34401884 Free PMC article.
We defined cohorts of vaccinated and unvaccinated individuals from Minnesota (n = 25,589 each) matched on age, sex, race, history of prior SARS-CoV-2 PCR testing, and date of full vaccination. Both vaccines were highly effective during this stud …
We defined cohorts of vaccinated and unvaccinated individuals from Minnesota (n = 25,589 each) matched on age, sex, race, history of prior …
Molnupiravir, an Oral Antiviral Treatment for COVID-19.
Fischer W, Eron JJ, Holman W, Cohen MS, Fang L, Szewczyk LJ, Sheahan TP, Baric R, Mollan KR, Wolfe CR, Duke ER, Azizad MM, Borroto-Esoda K, Wohl DA, Loftis AJ, Alabanza P, Lipansky F, Painter WP. Fischer W, et al. medRxiv. 2021 Jun 17:2021.06.17.21258639. doi: 10.1101/2021.06.17.21258639. Preprint. medRxiv. 2021. PMID: 34159342 Free PMC article. Updated.
BACKGROUND: Easily distributed oral antivirals are urgently needed to treat coronavirus disease-2019 (COVID-19), prevent progression to severe illness, and block transmission of severe acute respiratory syndrome co
BACKGROUND: Easily distributed oral antivirals are urgently needed to treat coronavirus disease-2019 (COVID-19), …
COVID-19 induces neuroinflammation and loss of hippocampal neurogenesis.
Klein R, Soung A, Sissoko C, Nordvig A, Canoll P, Mariani M, Jiang X, Bricker T, Goldman J, Rosoklija G, Arango V, Underwood M, Mann JJ, Boon A, Dowrk A, Boldrini M. Klein R, et al. Res Sq. 2021 Oct 29:rs.3.rs-1031824. doi: 10.21203/rs.3.rs-1031824/v1. Preprint. Res Sq. 2021. PMID: 34729556 Free PMC article.
Infection with the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is associated with onset of neurological and psychiatric symptoms during and after the acute phase of illness (1-4) . Acute
Infection with the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2
A humanized mouse model of chronic COVID-19 to evaluate disease mechanisms and treatment options.
Sefik E, Israelow B, Zhao J, Qu R, Song E, Mirza H, Kaffe E, Halene S, Meffre E, Kluger Y, Nussenzweig M, Wilen C, Iwasaki A, Flavell RA. Sefik E, et al. Res Sq. 2021 Mar 17:rs.3.rs-279341. doi: 10.21203/rs.3.rs-279341/v1. Preprint. Res Sq. 2021. PMID: 33758831 Free PMC article.
Coronavirus-associated acute respiratory disease, called coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-
Coronavirus-associated acute respiratory disease, called coronavirus disease 2019 (COVID-19
SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE2.
Lei Y, Zhang J, Schiavon CR, He M, Chen L, Shen H, Zhang Y, Yin Q, Cho Y, Andrade L, Shadel GS, Hepokoski M, Lei T, Wang H, Zhang J, Yuan JX, Malhotra A, Manor U, Wang S, Yuan ZY, Shyy JY. Lei Y, et al. bioRxiv. 2020 Dec 4:2020.12.04.409144. doi: 10.1101/2020.12.04.409144. Preprint. bioRxiv. 2020. PMID: 33300001 Free PMC article. Updated.
Coronavirus disease 2019 (COVID-19) includes the cardiovascular complications in addition to respiratory disease. ...SARS-CoV-2 infection relies on the binding of Spike glycoprotein (S protein) to angiotensin converting enzy
Coronavirus disease 2019 (COVID-19) includes the cardiovascular complications in addition to respiratory
COVID-19 vaccine impact on rates of SARS-CoV-2 cases and post vaccination strain sequences among healthcare workers at an urban academic medical center: a prospective cohort study.
Bouton TC, Lodi S, Turcinovic J, Weber SE, Quinn E, Korn C, Steiner J, Schechter-Perkins EM, Duffy E, Ragan EJ, Taylor BP, Schaeffer B, Miller N, Davidoff R, Hanage WP, Connor J, Pierre C, Jacobson KR. Bouton TC, et al. medRxiv. 2021 Apr 27:2021.03.30.21254655. doi: 10.1101/2021.03.30.21254655. Preprint. medRxiv. 2021. PMID: 33821283 Free PMC article. Updated.
BACKGROUND: COVID-19 vaccine trials and post-implementation data suggest vaccination decreases SARS-CoV-2 infections. ...MAIN POINT: Cases of SARS-CoV-2 among health care workers dropped rapidly with COVID-19 v …
BACKGROUND: COVID-19 vaccine trials and post-implementation data suggest vaccination decreases SARS-CoV-2
Negligible impact of SARS-CoV-2 variants on CD4 + and CD8 + T cell reactivity in COVID-19 exposed donors and vaccinees.
Tarke A, Sidney J, Methot N, Zhang Y, Dan JM, Goodwin B, Rubiro P, Sutherland A, da Silva Antunes R, Frazier A, Rawlings SA, Smith DM, Peters B, Scheuermann RH, Weiskopf D, Crotty S, Grifoni A, Sette A. Tarke A, et al. bioRxiv. 2021 Mar 1:2021.02.27.433180. doi: 10.1101/2021.02.27.433180. Preprint. bioRxiv. 2021. PMID: 33688655 Free PMC article. Updated.
It is important to address whether also CD4+ and CD8+ T cell responses are affected, because of the role they play in disease resolution and modulation of COVID-19 disease severity. Here we performed a comprehensive analysis of SARS-CoV-2-specif …
It is important to address whether also CD4+ and CD8+ T cell responses are affected, because of the role they play in disease resolution and …
RNA-Based COVID-19 Vaccine BNT162b2 Selected for a Pivotal Efficacy Study.
Walsh EE, Frenck R, Falsey AR, Kitchin N, Absalon J, Gurtman A, Lockhart S, Neuzil K, Mulligan MJ, Bailey R, Swanson KA, Li P, Koury K, Kalina W, Cooper D, Fontes-Garfias C, Shi PY, Türeci Ö, Thompkins KR, Lyke KE, Raabe V, Dormitzer PR, Jansen KU, Sahin U, Gruber WC. Walsh EE, et al. medRxiv. 2020 Aug 28:2020.08.17.20176651. doi: 10.1101/2020.08.17.20176651. Preprint. medRxiv. 2020. PMID: 32839784 Free PMC article. Updated.
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and the resulting disease, coronavirus disease 2019 (COVID-19), have spread to millions of people globall …
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infe …
Disruption of the CCL5/RANTES-CCR5 Pathway Restores Immune Homeostasis and Reduces Plasma Viral Load in Critical COVID-19.
Patterson BK, Seethamraju H, Dhody K, Corley MJ, Kazempour K, Lalezari JP, Pang AP, Sugai C, Francisco EB, Pise A, Rodrigues H, Ryou M, Wu HL, Webb GM, Park BS, Kelly S, Pourhassan N, Lelic A, Kdouh L, Herrera M, Hall E, Aklin E, Ndhlovu L, Sacha JB. Patterson BK, et al. medRxiv. 2020 May 5:2020.05.02.20084673. doi: 10.1101/2020.05.02.20084673. Preprint. medRxiv. 2020. PMID: 32511656 Free PMC article.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), is now pandemic with nearly three million cases reported to date. .
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative a
3,237 results