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1993 1
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Page 1
Safety and Efficacy of Pemivibart, a Long-Acting Monoclonal Antibody, for Prevention of Symptomatic COVID-19: Interim Results From a Phase 3 Randomized Clinical Trial (CANOPY).
Wolfe CR, Cohen J, Mahoney K, Holmes A, Betancourt N, Gupta D, Tosh K, Narayan K, Campanaro E, Katz C, Phelan AM, Yalcin I, Wingertzahn M, Hawn P, Schmidt P, Li Y, Popejoy M. Wolfe CR, et al. Clin Infect Dis. 2025 May 24:ciaf265. doi: 10.1093/cid/ciaf265. Online ahead of print. Clin Infect Dis. 2025. PMID: 40410927
METHODS: Eligible participants (18 years; negative for current SARS-CoV-2 infection) received 2 intravenous 4500-mg pemivibart infusions (cohort A) or were randomized 2:1 to receive blinded pemivibart or placebo (cohort B) 90 days apart. ...Composite incidenc …
METHODS: Eligible participants (18 years; negative for current SARS-CoV-2 infection) received 2 intravenous 4500-mg pem …
The feasibility and acceptability of implementing simplified cognitive behavioral therapy approaches to support postpartum mental health and address associated social and behavioral barriers to postpartum family planning in Amhara, Ethiopia: a qualitative study.
Burgess S, Bitew T, Haile A, Souffrant J, Shattuck D, Van Lith LM, Moore J, Hendrickson ZM. Burgess S, et al. BMC Womens Health. 2025 May 24;25(1):248. doi: 10.1186/s12905-025-03744-w. BMC Womens Health. 2025. PMID: 40410834
Quality and reliability of pediatric pneumonia related short videos on mainstream platforms: cross-sectional study.
He F, Yang M, Liu J, Gong T, Ma J, Yang T, Zhao D, Li S, Tian D. He F, et al. BMC Public Health. 2025 May 23;25(1):1896. doi: 10.1186/s12889-025-22963-2. BMC Public Health. 2025. PMID: 40410758
BACKGROUND: Pediatric pneumonia remains a major global health concern, accounting for one of the leading causes of mortality among children under five years of age. With the prevalence of COVID-19, public attention to pediatric pneumonia has significantly increased. …
BACKGROUND: Pediatric pneumonia remains a major global health concern, accounting for one of the leading causes of mortality among children …
Health inequities: a persistent global challenge from past to future.
Rad J. Rad J. Int J Equity Health. 2025 May 23;24(1):148. doi: 10.1186/s12939-025-02526-y. Int J Equity Health. 2025. PMID: 40410748
These disparities, historically influenced by colonial legacies and socio-economic inequality, persist into the present, with new challenges such as the COVID-19 pandemic and climate change further widening them. Looking ahead, the rise of digital health technologie …
These disparities, historically influenced by colonial legacies and socio-economic inequality, persist into the present, with new challenges …
Evaluation of broad-spectrum protection by novel mRNA vaccines against SARS-CoV-2 variants (Delta, Omicron-BA.5, XBB-EG.5) in the golden hamster model.
Yu T, Xing J, Zhuang X, Tian M. Yu T, et al. Virol J. 2025 May 24;22(1):159. doi: 10.1186/s12985-025-02787-7. Virol J. 2025. PMID: 40410742
Additionally, vaccinated animals exhibited significantly less lung damage as evidenced by both histological and immunofluorescence analyses, especially in groups vaccinated with RBD-Fe, RE-N, and COVID-19 epitope formulations. CONCLUSIONS: These mRNA vaccines demons …
Additionally, vaccinated animals exhibited significantly less lung damage as evidenced by both histological and immunofluorescence analyses, …
Educational utility of observational workplace-based assessment modalities in Australian vocational general practice training: a cross-sectional study.
Fielding A, Mundy B, Tapley A, Gani S, Ali R, Bentley M, Boland R, Zbaidi L, Holliday E, Ball J, van Driel M, Klein L, Magin P. Fielding A, et al. BMC Med Educ. 2025 May 23;25(1):762. doi: 10.1186/s12909-025-07328-y. BMC Med Educ. 2025. PMID: 40410727
Traditionally, ECTVs are conducted face-to-face, but the COVID-19 pandemic saw the development and implementation of remote ECTV modalities. It remains unknown if perceived educational utility of remote ECTVs differs from traditional face-to-face ECTVs. ...
Traditionally, ECTVs are conducted face-to-face, but the COVID-19 pandemic saw the development and implementation of remote EC …
Study on the influence of sports consumption decisions of college students in commercial fitness clubs in the post pandemic era of COVID- 19.
Chen Z, Zainuddin ZA, Xu M, Zhou N, Yan Y, Dong J. Chen Z, et al. BMC Public Health. 2025 May 23;25(1):1912. doi: 10.1186/s12889-025-22805-1. BMC Public Health. 2025. PMID: 40410725
Based on the social background of the post pandemic era of COVID-19, this study mainly uses thematic analysis and analytic hierarchy process to analyse the influencing factors of sports consumption decisions of college students in commercial fitness clubs in Donggua …
Based on the social background of the post pandemic era of COVID-19, this study mainly uses thematic analysis and analytic hie …
Impact of COVID-19 pandemic on glycaemic and blood pressure control among patients with type 2 diabetes in primary care in Hong Kong.
Wong CM, Lai KPL, Luk MHM, Chan PF. Wong CM, et al. BMC Prim Care. 2025 May 23;26(1):182. doi: 10.1186/s12875-025-02893-z. BMC Prim Care. 2025. PMID: 40410724
OBJECTIVES: To evaluate the impact of social distancing measures due to COVID-19 pandemic on glycemic and blood pressure control in primary care in Hong Kong. ...CONCLUSIONS: Despite the implementation of various social distancing measures resulting in significant c …
OBJECTIVES: To evaluate the impact of social distancing measures due to COVID-19 pandemic on glycemic and blood pressure contr …
Mucosal implications of oral Jak3-targeted drugs in COVID patients.
Kumar N, Segovia D, Kumar P, Atti HB, Kumar S, Mishra J. Kumar N, et al. Mol Med. 2025 May 23;31(1):203. doi: 10.1186/s10020-025-01260-z. Mol Med. 2025. PMID: 40410684 Review.
The JAK family, particularly JAK3, plays a crucial role in immune signaling and inflammatory responses. Dysregulated JAK3 activation in SARS-CoV-2 infections has been associated with severe inflammation and respiratory complications, making JAK inhibitors a v …
The JAK family, particularly JAK3, plays a crucial role in immune signaling and inflammatory responses. Dysregulated JAK3 activation in S …
Genome diversity of SARS-CoV-2 lineages associated with vaccination breakthrough infections in Addis Ababa, Ethiopia.
Aga AM, Mulugeta D, Gebreegziabxier A, Zeleke GT, Girmay AM, Tura GB, Ayele A, Mohammed A, Belete T, Taddele T, Abubeker R, Woldemariyam FT, Gelanew T, Tesera Y, Gidisa B, Tura JB, Leta GT, Ali A, Beshah SA, Likasa BW, Mohammed J, Nigussie D. Aga AM, et al. BMC Infect Dis. 2025 May 23;25(1):738. doi: 10.1186/s12879-025-11107-x. BMC Infect Dis. 2025. PMID: 40410660
BACKGROUND: Extensive vaccination campaigns against COVID-19 have played a significant role in controlling virus spread and preventing severe illness. This study focused on breakthrough infections in vaccinated individuals, raising concerns about vaccine effectivene …
BACKGROUND: Extensive vaccination campaigns against COVID-19 have played a significant role in controlling virus spread and pr …
Metabolic modeling elucidates phenformin and atpenin A5 as broad-spectrum antiviral drugs against RNA viruses.
Renz A, Hohner M, Jami R, Breitenbach M, Josephs-Spaulding J, Dürrwald J, Best L, Dulière V, Mialon C, Bader SM, Marinos G, Leonidou N, Cabreiro F, Pellegrini M, Doerflinger M, Rosa-Calatrava M, Pizzorno A, Dräger A, Schindler M, Kaleta C. Renz A, et al. Commun Biol. 2025 May 23;8(1):791. doi: 10.1038/s42003-025-08148-y. Commun Biol. 2025. PMID: 40410544
The SARS-CoV-2 pandemic has reemphasized the urgent need for broad-spectrum antiviral therapies. ...Indeed, phenformin, an NADH:ubiquinone oxidoreductase inhibitor, suppressed SARS-CoV-2 and dengue virus replication. Atpenin A5, blocking …
The SARS-CoV-2 pandemic has reemphasized the urgent need for broad-spectrum antiviral therapies. ...Indeed, phenformin, …
Impact of COVID-19 on the epidemiology of severe sinogenic and otogenic infections and their intracranial complications.
Dimopoulou D, Berikopoulou MM, Tsoliakos I, Michos A. Dimopoulou D, et al. Eur J Pediatr. 2025 May 24;184(6):359. doi: 10.1007/s00431-025-06188-4. Eur J Pediatr. 2025. PMID: 40410442
WHAT IS KNOWN: The COVID-19 pandemic shifted the epidemiology of severe upper respiratory tract infections. Data on the epidemiology of severe sinogenic and otogenic infections and their intracranial complications during and after the acute phase of the COVID …
WHAT IS KNOWN: The COVID-19 pandemic shifted the epidemiology of severe upper respiratory tract infections. Data on the epidem …
Uniform temperature distribution in microwave heating achieved via rotating electric field.
Seo J, Han G, Hwang H. Seo J, et al. Sci Rep. 2025 May 23;15(1):17960. doi: 10.1038/s41598-025-03373-1. Sci Rep. 2025. PMID: 40410358
The temperature coefficient of variation (COV) was successfully reduced to below 5%, clearly demonstrating the system's capability to significantly improve uniformity in microwave heating. ...
The temperature coefficient of variation (COV) was successfully reduced to below 5%, clearly demonstrating the system's capability to …
Addressing survey fatigue bias in longitudinal social contact studies to improve pandemic preparedness.
Dan S, Ling Z, Chen Y, Tegegne J, Jaeger VK, Karch A, Mishra S, Ratmann O; Machine Learning &Global Health network. Dan S, et al. Sci Rep. 2025 May 23;15(1):17935. doi: 10.1038/s41598-025-02235-0. Sci Rep. 2025. PMID: 40410335
Numerous longitudinal social contact surveys were conducted during the COVID-19 era, however data analysis is plagued by survey fatigue, a phenomenon whereby the average number of social contacts reported declines with the number of repeat participations and as part …
Numerous longitudinal social contact surveys were conducted during the COVID-19 era, however data analysis is plagued by surve …
Automated depression detection via cloud based EEG analysis with transfer learning and synchrosqueezed wavelet transform.
Bagherzadeh S, Norouzi MR, Ghasri A, Tolou Kouroshi P, Bahri Hampa S, Farokhshad F, Shalbaf A. Bagherzadeh S, et al. Sci Rep. 2025 May 23;15(1):18008. doi: 10.1038/s41598-025-02452-7. Sci Rep. 2025. PMID: 40410314
Post-COVID-19, depression rates have risen sharply, increasing the need for early diagnosis using electroencephalogram (EEG) and deep learning. ...
Post-COVID-19, depression rates have risen sharply, increasing the need for early diagnosis using electroencephalogram (EEG) a …
Cardiac risk in recovered Covid-19 patients evaluated by (123)I-mIBG.
Liebich A, Sheikh G, Bundschuh RA, Kircher M, Dierks A, Nittbaur B, Raake P, Rieger M, Higuchi T, Pfob CH, Lapa C. Liebich A, et al. Sci Rep. 2025 May 23;15(1):18039. doi: 10.1038/s41598-025-02212-7. Sci Rep. 2025. PMID: 40410298
To determine whether cardiac sympathetic nervous dysfunction is present, in this single center prospective, non-randomized trial non-invasive SPECT/CT imaging using the radiotracer (123)I-metaiodobenzylguanidine was performed in 33 recovered COVID-19 patients withou …
To determine whether cardiac sympathetic nervous dysfunction is present, in this single center prospective, non-randomized trial non-invasiv …
Indirect effect of the COVID-19 pandemic on cardiovascular diseases incidence, mortality, and healthcare use among patients with hypertension but without SARS-CoV-2 infection in Hong Kong: an interrupted time series analysis.
Hu Z, Yau YK, Quan J, Grépin KA, Mak IL, Lau GKK, Wong ICK, Chao DVK, Ko WWK, Lau CS, Lam CLK, Wan EYF. Hu Z, et al. Hypertens Res. 2025 May 23. doi: 10.1038/s41440-025-02230-y. Online ahead of print. Hypertens Res. 2025. PMID: 40410292
This study investigated the effects of the COVID-19 pandemic on cardiovascular disease (CVD) incidence among hypertensive patients without SARS-CoV-2 infection by changes in CVD incidence, all-cause mortality, blood pressure (BP) control, and he …
This study investigated the effects of the COVID-19 pandemic on cardiovascular disease (CVD) incidence among hypertensive pati …
Spermidine reduces ISGylation and enhances ISG15-USP18 interaction.
Etori H, Asoshina R, Obita T, Okumura F. Etori H, et al. Sci Rep. 2025 May 23;15(1):17913. doi: 10.1038/s41598-025-01425-0. Sci Rep. 2025. PMID: 40410283
ISG15 is removed from substrates by interferon-induced ubiquitin-specific peptidase 18 (USP18) or severe acute respiratory syndrome coronavirus 2-derived papain-like protease. High ISGylation levels may help prevent the spread of coron …
ISG15 is removed from substrates by interferon-induced ubiquitin-specific peptidase 18 (USP18) or severe acute respiratory …
Results of a multi-perspective examination of loneliness trajectories and its determinants in German adults during the COVID-19 pandemic.
Reinwarth AC, Ernst M, Gerstorf D, Brähler E, Wild PS, Münzel T, König J, Lackner KJ, Pfeiffer N, Beutel ME. Reinwarth AC, et al. Sci Rep. 2025 May 23;15(1):17889. doi: 10.1038/s41598-025-00678-z. Sci Rep. 2025. PMID: 40410266
Analyses included two measurement points before and two during the pandemic, combining data from the population-based Gutenberg Health Study and COVID-19 Study (N = 7001; baseline: M(age) = 51.72, SD(age) = 10.04). Growth mixture models identified distinct lonelines …
Analyses included two measurement points before and two during the pandemic, combining data from the population-based Gutenberg Health Study …
QSPR and QSTR analysis to explore pharmacokinetic and toxicity properties of antifungal drugs through topological descriptors.
Tamilarasi W, Balamurugan BJ. Tamilarasi W, et al. Sci Rep. 2025 May 23;15(1):18020. doi: 10.1038/s41598-025-01522-0. Sci Rep. 2025. PMID: 40410226
COVID-19 patients often develop serious fungal infections like Aspergillosis, Candidiasis, and Mucormycosis, which are treated with antifungal drugs like Amphotericin B, Posaconazole, and Isavuconazole. ...These insights are crucial for advancing more effective anti …
COVID-19 patients often develop serious fungal infections like Aspergillosis, Candidiasis, and Mucormycosis, which are treated …
476,806 results
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