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Page 1
Increased virulence of coxsackievirus B3 in mice due to vitamin E or selenium deficiency.
Beck MA. Beck MA. J Nutr. 1997 May;127(5 Suppl):966S-970S. doi: 10.1093/jn/127.5.966S. J Nutr. 1997. PMID: 9164275 Review.
That is, if the nutritional status of the host is poor-due to either single or multiple nutrient deficiencies-then the functioning of the host immune system is compromised. This impairment of the immune response will lead to an increased susceptibility to infectious diseas …
That is, if the nutritional status of the host is poor-due to either single or multiple nutrient deficiencies-then the functioning of …
Selenium deficiency and viral infection.
Beck MA, Levander OA, Handy J. Beck MA, et al. J Nutr. 2003 May;133(5 Suppl 1):1463S-7S. doi: 10.1093/jn/133.5.1463S. J Nutr. 2003. PMID: 12730444 Review.
The discovery that the juvenile cardiomyopathy known as Keshan disease likely has a dual etiology that involves both a nutritional deficiency of the essential trace mineral selenium (Se) as well as an infection with an enterovirus provided the impetus for add …
The discovery that the juvenile cardiomyopathy known as Keshan disease likely has a dual etiology that involves both a nutritional defici …
Selenium and viral virulence.
Levander OA, Beck MA. Levander OA, et al. Br Med Bull. 1999;55(3):528-33. doi: 10.1258/0007142991902592. Br Med Bull. 1999. PMID: 10746343
A mouse model of coxsackievirus-induced myocarditis is being used to investigate nutritional determinants of viral virulence. ...Selenium deficiency in our mice increased the virulence of an already virulent strain of coxsackievirus …
A mouse model of coxsackievirus-induced myocarditis is being used to investigate nutritional determinants of viral virulence. …
Copper deficiency increases the virulence of amyocarditic and myocarditic strains of coxsackievirus B3 in mice.
Smith AD, Botero S, Levander OA. Smith AD, et al. J Nutr. 2008 May;138(5):849-55. doi: 10.1093/jn/138.5.849. J Nutr. 2008. PMID: 18424590 Free article.
Deficiency in several trace elements, including copper and selenium, is associated with increased levels of oxidative stress. Copper deficiency also has been shown to impair immune function. Previous work by others demonstrated that passage of an amyocarditic …
Deficiency in several trace elements, including copper and selenium, is associated with increased levels of oxidative stress. …
Increased virulence of a human enterovirus (coxsackievirus B3) in selenium-deficient mice.
Beck MA, Kolbeck PC, Shi Q, Rohr LH, Morris VC, Levander OA. Beck MA, et al. J Infect Dis. 1994 Aug;170(2):351-7. doi: 10.1093/infdis/170.2.351. J Infect Dis. 1994. PMID: 8035022
Coxsackievirus B3 (CVB3/20)-induced myocarditic lesions occurred more quickly and were more severe and virus titers in heart and liver were higher in selenium (Se)-deficient than Se-adequate mice. ...Thus, the general population of CVB3/20 virions, as a conse …
Coxsackievirus B3 (CVB3/20)-induced myocarditic lesions occurred more quickly and were more severe and virus titers in heart and live …
Rapid genomic evolution of a non-virulent coxsackievirus B3 in selenium-deficient mice.
Beck MA. Beck MA. Biomed Environ Sci. 1997 Sep;10(2-3):307-15. Biomed Environ Sci. 1997. PMID: 9315324 Review.
Using a murine model of coxsackievirus B3 (CVB3)-induced myocarditis, Se-deficient mice were shown to be more susceptible to the cardiopathologic effects of the virus. In addition, a normal benign strain of CVB3 becomes virulent in Se-deficient mice. T …
Using a murine model of coxsackievirus B3 (CVB3)-induced myocarditis, Se-deficient mice were shown to be more susceptible to t …
Effect of gold(I) compounds on the virulence of an amyocarditic strain of coxsackievirus B3.
Smith AD, South PK, Levander OA. Smith AD, et al. Biol Trace Elem Res. 2001 Winter;84(1-3):67-80. doi: 10.1385/BTER:84:1-3:067. Biol Trace Elem Res. 2001. PMID: 11817697
Both amyocardititc and myocarditic strains exist and at least one amyocarditic strain, CVB3/0, can convert to virulence when passaged through selenium or vitamin E-deficient mice. Gold(I)-containing compounds, such as aurothiomalate (ATM) and aurothioglucose …
Both amyocardititc and myocarditic strains exist and at least one amyocarditic strain, CVB3/0, can convert to virulence when passaged …
The relevance of selenium to viral disease with special reference to SARS-CoV-2 and COVID-19.
Rayman MP, Taylor EW, Zhang J. Rayman MP, et al. Proc Nutr Soc. 2023 Feb;82(1):1-12. doi: 10.1017/S0029665122002646. Epub 2022 Aug 19. Proc Nutr Soc. 2023. PMID: 35983618 Review.
In this review, the relevance of selenium (Se) to viral disease will be discussed paying particular attention to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease (COVID-19). Se, the active centre in selenoproteins has an ongoing history …
In this review, the relevance of selenium (Se) to viral disease will be discussed paying particular attention to severe acute respira …
Selenium and host defence towards viruses.
Beck MA. Beck MA. Proc Nutr Soc. 1999 Aug;58(3):707-11. doi: 10.1017/s0029665199000920. Proc Nutr Soc. 1999. PMID: 10604206 Review.
We have demonstrated that a normally-benign strain of coxsackievirus B3 (CVB3/0) becomes virulent in either Se-deficient or vitamin E-deficient mice. Although the deficient animals are immunosuppressed, the virus itself is also altered. Six nucl …
We have demonstrated that a normally-benign strain of coxsackievirus B3 (CVB3/0) becomes virulent in either Se-deficient …
Micronutrients and host resistance to viral infection.
Beck MA, Matthews CC. Beck MA, et al. Proc Nutr Soc. 2000 Nov;59(4):581-5. doi: 10.1017/s0029665100000823. Proc Nutr Soc. 2000. PMID: 11115793 Review.
Previous work in our laboratory demonstrated that a virus could undergo rapid mutation in a host deficient in Se, leading to a normally avirulent virus acquiring virulence due to genome changes. ...How the alteration of the immune response of the Se-deficient …
Previous work in our laboratory demonstrated that a virus could undergo rapid mutation in a host deficient in Se, leading to a normal …
28 results