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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1855 2
1908 1
1909 2
1910 2
1911 3
1912 4
1913 1
1915 2
1916 1
1917 1
1918 2
1920 1
1923 2
1925 1
1926 1
1928 2
1929 2
1930 1
1931 4
1932 3
1933 3
1934 3
1935 2
1936 2
1937 3
1938 4
1939 2
1940 2
1943 3
1944 2
1945 9
1946 17
1947 28
1948 30
1949 21
1950 40
1951 45
1952 30
1953 33
1954 42
1955 38
1956 38
1957 46
1958 40
1959 43
1960 47
1961 87
1962 100
1963 222
1964 438
1965 355
1966 380
1967 416
1968 362
1969 357
1970 397
1971 466
1972 484
1973 516
1974 556
1975 617
1976 595
1977 669
1978 643
1979 772
1980 758
1981 722
1982 794
1983 876
1984 874
1985 963
1986 968
1987 929
1988 980
1989 1083
1990 1145
1991 1122
1992 1125
1993 1128
1994 1163
1995 1125
1996 1127
1997 1136
1998 1241
1999 1244
2000 1333
2001 1333
2002 1306
2003 1423
2004 1367
2005 1427
2006 1623
2007 1639
2008 1546
2009 1614
2010 1664
2011 1732
2012 1882
2013 1963
2014 1931
2015 1928
2016 1934
2017 1903
2018 1837
2019 1853
2020 2292
2021 2436
2022 2353
2023 1993
2024 901

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67,829 results

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Page 1
Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?
Antonio J, Candow DG, Forbes SC, Gualano B, Jagim AR, Kreider RB, Rawson ES, Smith-Ryan AE, VanDusseldorp TA, Willoughby DS, Ziegenfuss TN. Antonio J, et al. J Int Soc Sports Nutr. 2021 Feb 8;18(1):13. doi: 10.1186/s12970-021-00412-w. J Int Soc Sports Nutr. 2021. PMID: 33557850 Free PMC article. Review.
7. Does creatine increase fat mass? 8. Is a creatine 'loading-phase' required? ...11. Is creatine only effective for males? 12. Are other forms of creatine similar or superior to monohydrate and is creatine stable in solutions/beverages? ...
7. Does creatine increase fat mass? 8. Is a creatine 'loading-phase' required? ...11. Is creatine only effective for ma …
Effects of Creatine Supplementation on Brain Function and Health.
Forbes SC, Cordingley DM, Cornish SM, Gualano B, Roschel H, Ostojic SM, Rawson ES, Roy BD, Prokopidis K, Giannos P, Candow DG. Forbes SC, et al. Nutrients. 2022 Feb 22;14(5):921. doi: 10.3390/nu14050921. Nutrients. 2022. PMID: 35267907 Free PMC article. Review.
Preliminary studies indicate that creatine supplementation (and guanidinoacetic acid; GAA) has the ability to increase brain creatine content in humans. ...The purpose of this narrative review is to summarize the current body of research pertaining to creatine
Preliminary studies indicate that creatine supplementation (and guanidinoacetic acid; GAA) has the ability to increase brain creat
Creatine Use in Sports.
Butts J, Jacobs B, Silvis M. Butts J, et al. Sports Health. 2018 Jan/Feb;10(1):31-34. doi: 10.1177/1941738117737248. Epub 2017 Oct 23. Sports Health. 2018. PMID: 29059531 Free PMC article. Review.
EVIDENCE ACQUISITION: PubMed was searched for articles published between 1980 and January 2017 using the terms creatine, creatine supplementation, sports performance, and dietary supplements. ...CONCLUSION: While creatine appears to be safe and effective for …
EVIDENCE ACQUISITION: PubMed was searched for articles published between 1980 and January 2017 using the terms creatine, creatine
Timing of Creatine Supplementation around Exercise: A Real Concern?
Ribeiro F, Longobardi I, Perim P, Duarte B, Ferreira P, Gualano B, Roschel H, Saunders B. Ribeiro F, et al. Nutrients. 2021 Aug 19;13(8):2844. doi: 10.3390/nu13082844. Nutrients. 2021. PMID: 34445003 Free PMC article. Review.
Furthermore, physiological and mechanistic data are lacking, in regard to claims that the timing of creatine supplementation around exercise moderates gains in muscle creatine and exercise performance. This review discusses novel scientific evidence on the timing of …
Furthermore, physiological and mechanistic data are lacking, in regard to claims that the timing of creatine supplementation around e …
Creatine and creatinine metabolism.
Wyss M, Kaddurah-Daouk R. Wyss M, et al. Physiol Rev. 2000 Jul;80(3):1107-213. doi: 10.1152/physrev.2000.80.3.1107. Physiol Rev. 2000. PMID: 10893433 Free article. Review.
The goal of this review is to present a comprehensive survey of the many intriguing facets of creatine (Cr) and creatinine metabolism, encompassing the pathways and regulation of Cr biosynthesis and degradation, species and tissue distribution of the enzymes and metabolite …
The goal of this review is to present a comprehensive survey of the many intriguing facets of creatine (Cr) and creatinine metabolism …
Creatine and multiple sclerosis.
Ostojic SM. Ostojic SM. Nutr Neurosci. 2022 May;25(5):912-919. doi: 10.1080/1028415X.2020.1819108. Epub 2020 Sep 11. Nutr Neurosci. 2022. PMID: 32912105 Review.
This review summarizes human trials describing alterations in creatine levels in the nervous system and other tissues during MS, affects how certain medications for MS affect brain creatine concentrations, and discusses a possible demand for exogenous creatine
This review summarizes human trials describing alterations in creatine levels in the nervous system and other tissues during MS, affe …
Creatine, Creatine Kinase, and Aging.
Sumien N, Shetty RA, Gonzales EB. Sumien N, et al. Subcell Biochem. 2018;90:145-168. doi: 10.1007/978-981-13-2835-0_6. Subcell Biochem. 2018. PMID: 30779009 Review.
The goal of this chapter is to summarize how creatine and its associated enzyme, creatine kinase, act under normal physiological conditions, and how altered levels of either may lead to detrimental functional outcomes. Furthermore, we will focus on the effect of agi …
The goal of this chapter is to summarize how creatine and its associated enzyme, creatine kinase, act under normal physiologic …
Creatine supplementation and endurance performance: surges and sprints to win the race.
Forbes SC, Candow DG, Neto JHF, Kennedy MD, Forbes JL, Machado M, Bustillo E, Gomez-Lopez J, Zapata A, Antonio J. Forbes SC, et al. J Int Soc Sports Nutr. 2023 Dec;20(1):2204071. doi: 10.1080/15502783.2023.2204071. J Int Soc Sports Nutr. 2023. PMID: 37096381 Free PMC article. Review.
In addition, creatine lowers inflammation and oxidative stress and has the potential to increase mitochondrial biogenesis. ...Given creatines ability to enhance anaerobic work capacity and performance through repeated surges in intensity, creatine supplementa …
In addition, creatine lowers inflammation and oxidative stress and has the potential to increase mitochondrial biogenesis. ...Given …
Studies on the safety of creatine supplementation.
Kim HJ, Kim CK, Carpentier A, Poortmans JR. Kim HJ, et al. Amino Acids. 2011 May;40(5):1409-18. doi: 10.1007/s00726-011-0878-2. Epub 2011 Mar 12. Amino Acids. 2011. PMID: 21399917 Review.
Doubtful allegations of adverse effects of creatine supplementation have been released through the press media and through scientific publications. ...Anecdotal reports from athletes have appeared on muscle cramp and gastrointestinal complaints during creatine suppl …
Doubtful allegations of adverse effects of creatine supplementation have been released through the press media and through scientific …
Anti-Inflammatory and Anti-Catabolic Effects of Creatine Supplementation: A Brief Review.
Cordingley DM, Cornish SM, Candow DG. Cordingley DM, et al. Nutrients. 2022 Jan 27;14(3):544. doi: 10.3390/nu14030544. Nutrients. 2022. PMID: 35276903 Free PMC article. Review.
Emerging research also indicates that creatine supplementation may have favorable effects on measures of bone biology. ...Creatine supplementation has the ability to decrease markers of inflammation and possibly attenuate cancerous tumor growth progression. ...
Emerging research also indicates that creatine supplementation may have favorable effects on measures of bone biology. ...Creatine
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