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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1970 1
1973 1
1975 1
1976 1
1977 2
1978 1
1979 3
1980 2
1981 3
1982 3
1983 3
1984 4
1985 9
1986 5
1987 9
1988 10
1989 15
1990 19
1991 19
1992 12
1993 7
1994 14
1995 7
1996 12
1997 16
1998 11
1999 9
2000 7
2001 14
2002 6
2003 5
2004 7
2005 11
2006 8
2007 11
2008 7
2009 4
2010 6
2011 13
2012 11
2013 14
2014 10
2015 8
2016 4
2017 8
2018 4
2019 3
2020 5
2021 2
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352 results
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Page 1
Mitochondrial creatine kinase in human health and disease.
Schlattner U, Tokarska-Schlattner M, Wallimann T. Schlattner U, et al. Biochim Biophys Acta. 2006 Feb;1762(2):164-80. doi: 10.1016/j.bbadis.2005.09.004. Epub 2005 Sep 27. Biochim Biophys Acta. 2006. PMID: 16236486 Free article. Review.
Under situations of compromised cellular energy state, which are often linked to ischemia, oxidative stress and calcium overload, two characteristics of mitochondrial creatine kinase are particularly relevant: its exquisite susceptibility to oxidative modifications and the compen …
Under situations of compromised cellular energy state, which are often linked to ischemia, oxidative stress and calcium overload, two charac …
Creatine kinase, energy reserve, and hypertension: from bench to bedside.
Brewster LM. Brewster LM. Ann Transl Med. 2018 Aug;6(15):292. doi: 10.21037/atm.2018.07.15. Ann Transl Med. 2018. PMID: 30211180 Free PMC article. Review.
Importantly, high tissue CK preceded hypertension in animal models and in humans, and human vascular tissue CK gene expression was strongly associated with clinical blood pressure. ...
Importantly, high tissue CK preceded hypertension in animal models and in humans, and human vascular tissue CK gene expression was st …
Early evolution of the creatine kinase gene family and the capacity for creatine biosynthesis and membrane transport.
Ellington WR, Suzuki T. Ellington WR, et al. Subcell Biochem. 2007;46:17-26. doi: 10.1007/978-1-4020-6486-9_2. Subcell Biochem. 2007. PMID: 18652070 Review.
Conventional wisdom would suggest that CK evolved from an ancestral protein most similar to the CK homologue, arginine kinase. This early CK gene subsequently diverged into the cytoplasmic, mitochondrial and flagellar CK gene families. It is now clear that both the …
Conventional wisdom would suggest that CK evolved from an ancestral protein most similar to the CK homologue, arginine kinase. This early CK …
Structure and function of resistance arteries from BB-creatine kinase and ubiquitous Mt-creatine kinase double knockout mice.
Taherzadeh Z, van Montfrans GA, Van der Zee CEEM, Streijger F, Bakker ENTP, Brewster LM. Taherzadeh Z, et al. Amino Acids. 2020 Jul;52(6-7):1033-1041. doi: 10.1007/s00726-020-02872-x. Epub 2020 Jul 21. Amino Acids. 2020. PMID: 32696177
The mitochondrial isoenzyme catalyses phosphocreatine synthesis from ATP, while cytoplasmic CK, predominantly the BB isoenzyme in vascular tissue, is tightly bound near myosin ATPase, where it favours ATP production from phosphocreatine to metabolically support vascular contracti …
The mitochondrial isoenzyme catalyses phosphocreatine synthesis from ATP, while cytoplasmic CK, predominantly the BB isoenzyme in vascular t …
[Dangerous fortune: creatine kinase and blood pressure].
Brewster LM, van Montfrans GA. Brewster LM, et al. Ned Tijdschr Geneeskd. 2012;156(51):A5785. Ned Tijdschr Geneeskd. 2012. PMID: 23249518 Review. Dutch.
The thrifty gene hypothesis describes characteristics of 'thrifty' genes that were historically advantageous for survival, but may have become detrimental in modern times. ...
The thrifty gene hypothesis describes characteristics of 'thrifty' genes that were historically advantageous for survival, but …
Molecular Characterization and Expression Analysis of Creatine Kinase Muscle (CK-M) Gene in Horse.
Do KT, Cho HW, Badrinath N, Park JW, Choi JY, Chung YH, Lee HK, Song KD, Cho BW. Do KT, et al. Asian-Australas J Anim Sci. 2015 Dec;28(12):1680-5. doi: 10.5713/ajas.15.0468. Asian-Australas J Anim Sci. 2015. PMID: 26580434 Free PMC article.
An evolutionary study by synonymous and non-synonymous single nucleotide polymorphism ratio of CK-M gene revealed a positive selection that was conserved in the horse. More studies are warranted in order to develop the expression of CK-M gene as a biomarker in blood …
An evolutionary study by synonymous and non-synonymous single nucleotide polymorphism ratio of CK-M gene revealed a positive selectio …
Resistance artery creatine kinase mRNA and blood pressure in humans.
Karamat FA, Oudman I, Ris-Stalpers C, Afink GB, Keijser R, Clark JF, van Montfrans GA, Brewster LM. Karamat FA, et al. Hypertension. 2014 Jan;63(1):68-73. doi: 10.1161/HYPERTENSIONAHA.113.01352. Epub 2013 Oct 14. Hypertension. 2014. PMID: 24126179
Expression and localization of creatine kinase in the preimplantation embryo.
Forsey KE, Ellis PJ, Sargent CA, Sturmey RG, Leese HJ. Forsey KE, et al. Mol Reprod Dev. 2013 Mar;80(3):185-92. doi: 10.1002/mrd.22146. Epub 2013 Jan 28. Mol Reprod Dev. 2013. PMID: 23280606
Using quantitative PCR, transcripts of four subunit isoforms of CK--CKM, CKB, CKMT1, and CKMT2--were detectable at all developmental stages, from the presumptive zygote to late blastocyst, but there was no obvious pattern in gene expression. By contrast, total CK biochemic …
Using quantitative PCR, transcripts of four subunit isoforms of CK--CKM, CKB, CKMT1, and CKMT2--were detectable at all developmental stages, …
Creatine kinase MM TaqI and methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms influence exercise-induced C-reactive protein levels.
Miranda-Vilela AL, Akimoto AK, Lordelo GS, Pereira LC, Grisolia CK, Klautau-Guimarães Mde N. Miranda-Vilela AL, et al. Eur J Appl Physiol. 2012 Jan;112(1):183-92. doi: 10.1007/s00421-011-1967-3. Epub 2011 Apr 23. Eur J Appl Physiol. 2012. PMID: 21516340
Acute strenuous exercise almost certainly exceeds the benefits of physical activity; it can compromise performance and may contribute to increased future risk of cardiovascular disease (CVD) in athletes. Polymorphisms in the muscle-type creatine kinase (CK-MM) gene may inf …
Acute strenuous exercise almost certainly exceeds the benefits of physical activity; it can compromise performance and may contribute to inc …
Creatine kinase MM TaqI and methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms influence exercise-induced C-reactive protein levels.
Miranda-Vilela AL, Akimoto AK, Lordelo GS, Pereira LC, Grisolia CK, Klautau-Guimarães Mde N. Miranda-Vilela AL, et al. Eur J Appl Physiol. 2012 Mar;112(3):941-50. doi: 10.1007/s00421-011-1961-9. Epub 2011 Jun 26. Eur J Appl Physiol. 2012. PMID: 21706313
Acute strenuous exercise almost certainly exceeds the benefits of physical activity; it can compromise performance and may contribute to increased future risk of cardiovascular disease (CVD) in athletes. Polymorphisms in the muscle-type creatine kinase (CK-MM) gene may inf …
Acute strenuous exercise almost certainly exceeds the benefits of physical activity; it can compromise performance and may contribute to inc …
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