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1,251 results

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Page 1
Society of Critical Care Medicine and the Infectious Diseases Society of America Guidelines for Evaluating New Fever in Adult Patients in the ICU.
O'Grady NP, Alexander E, Alhazzani W, Alshamsi F, Cuellar-Rodriguez J, Jefferson BK, Kalil AC, Pastores SM, Patel R, van Duin D, Weber DJ, Deresinski S. O'Grady NP, et al. Crit Care Med. 2023 Nov 1;51(11):1570-1586. doi: 10.1097/CCM.0000000000006022. Epub 2023 Oct 12. Crit Care Med. 2023. PMID: 37902340
OBJECTIVES: This is an update of the 2008 Infectious Diseases Society of America and Society (IDSA) and Society of Critical Care Medicine (SCCM) guideline for the evaluation of new-onset fever in adult ICU patients without severe immunocompromise, now using the Grad …
OBJECTIVES: This is an update of the 2008 Infectious Diseases Society of America and Society (IDSA) and Society of Critical Care …
European Society of Clinical Microbiology and Infectious Diseases (ESCMID) guidelines for the treatment of infections caused by multidrug-resistant Gram-negative bacilli (endorsed by European society of intensive care medicine).
Paul M, Carrara E, Retamar P, Tängdén T, Bitterman R, Bonomo RA, de Waele J, Daikos GL, Akova M, Harbarth S, Pulcini C, Garnacho-Montero J, Seme K, Tumbarello M, Lindemann PC, Gandra S, Yu Y, Bassetti M, Mouton JW, Tacconelli E, Rodríguez-Baño J. Paul M, et al. Clin Microbiol Infect. 2022 Apr;28(4):521-547. doi: 10.1016/j.cmi.2021.11.025. Epub 2021 Dec 16. Clin Microbiol Infect. 2022. PMID: 34923128 Free article.
Treatments were classified as head-to-head comparisons between individual antibiotics and between monotherapy and combination therapy regimens, including defined monotherapy and combination regimens only. The primary outcome was all-cause mortality, preferably at 30 days a …
Treatments were classified as head-to-head comparisons between individual antibiotics and between monotherapy and combination therapy regime …
Nosocomial Infection.
Kollef MH, Torres A, Shorr AF, Martin-Loeches I, Micek ST. Kollef MH, et al. Crit Care Med. 2021 Feb 1;49(2):169-187. doi: 10.1097/CCM.0000000000004783. Crit Care Med. 2021. PMID: 33438970 Review.
OBJECTIVE: The first 70 years of critical care can be considered a period of "industrial revolution-like" advancement in terms of progressing the understanding and care of critical illness. ...Increasing virulence and antimicrobial resistance …
OBJECTIVE: The first 70 years of critical care can be considered a period of "industrial revolution-like" advancement in terms …
Management of pneumonia in critically ill patients.
Cillóniz C, Torres A, Niederman MS. Cillóniz C, et al. BMJ. 2021 Dec 6;375:e065871. doi: 10.1136/bmj-2021-065871. BMJ. 2021. PMID: 34872910 Review.
Identifying the underlying causative pathogen is also critical for antimicrobial stewardship. However, establishing an etiological diagnosis is challenging in most patients, especially in those with chronic underlying disease; those who received previous antibiotic …
Identifying the underlying causative pathogen is also critical for antimicrobial stewardship. However, establishing an etiolog …
ICU-acquired infections in immunocompromised patients.
Kreitmann L, Helms J, Martin-Loeches I, Salluh J, Poulakou G, Pène F, Nseir S. Kreitmann L, et al. Intensive Care Med. 2024 Mar;50(3):332-349. doi: 10.1007/s00134-023-07295-2. Epub 2024 Jan 10. Intensive Care Med. 2024. PMID: 38197931 Review.
Immunocompromised patients account for an increasing proportion of the typical intensive care unit (ICU) case-mix. Because of the increased availability of new drugs for cancer and auto-immune diseases, and improvement in the care of the most severely immunocompromi …
Immunocompromised patients account for an increasing proportion of the typical intensive care unit (ICU) case-mix. Because of the inc …
Antimicrobial Stewardship in the ICU.
Murphy CV, Reed EE, Herman DD, Magrum B, Beatty JJ, Stevenson KB. Murphy CV, et al. Semin Respir Crit Care Med. 2022 Feb;43(1):131-140. doi: 10.1055/s-0041-1740977. Epub 2022 Feb 16. Semin Respir Crit Care Med. 2022. PMID: 35172363 Review.
Integration of critical care practitioners into the initiatives of antimicrobial stewardship programs is key to their success. This review summarizes key components of antimicrobial stewardship programs and mechanisms for critical care pr …
Integration of critical care practitioners into the initiatives of antimicrobial stewardship programs is key to their s …
Linezolid: a review of its properties, function, and use in critical care.
Hashemian SMR, Farhadi T, Ganjparvar M. Hashemian SMR, et al. Drug Des Devel Ther. 2018 Jun 18;12:1759-1767. doi: 10.2147/DDDT.S164515. eCollection 2018. Drug Des Devel Ther. 2018. PMID: 29950810 Free PMC article. Review.
Mutation of 23S rRNA was shown to be a linezolid resistance mechanism. Besides, mutations in specific regions of ribosomal proteins uL3 and uL4 are increasingly associated with linezolid resistance. However, these proteins are located further away from the bound …
Mutation of 23S rRNA was shown to be a linezolid resistance mechanism. Besides, mutations in specific regions of ribosomal proteins u …
Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012.
Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb SA, Beale RJ, Vincent JL, Moreno R; Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup. Dellinger RP, et al. Crit Care Med. 2013 Feb;41(2):580-637. doi: 10.1097/CCM.0b013e31827e83af. Crit Care Med. 2013. PMID: 23353941 Free article.
Recommendations were classified into three groups: 1) those directly targeting severe sepsis; 2) those targeting general care of the critically ill patient and considered high priority in severe sepsis; and 3) pediatric considerations. ...CONCLUSIONS: Strong agreement exis …
Recommendations were classified into three groups: 1) those directly targeting severe sepsis; 2) those targeting general care of the …
Antibiotic Use in the Intensive Care Unit: Optimization and De-Escalation.
Campion M, Scully G. Campion M, et al. J Intensive Care Med. 2018 Dec;33(12):647-655. doi: 10.1177/0885066618762747. Epub 2018 Mar 13. J Intensive Care Med. 2018. PMID: 29534630 Review.
Appropriate antimicrobial therapy is essential to ensuring positive patient outcomes. Inappropriate or suboptimal utilization of antibiotics can lead to increased length of stay, multidrug-resistant infections, and mortality. ...These strategies for antibiotic use h …
Appropriate antimicrobial therapy is essential to ensuring positive patient outcomes. Inappropriate or suboptimal utilization …
Treatment of severe skin and soft tissue infections: a review.
Burnham JP, Kollef MH. Burnham JP, et al. Curr Opin Infect Dis. 2018 Apr;31(2):113-119. doi: 10.1097/QCO.0000000000000431. Curr Opin Infect Dis. 2018. PMID: 29278528 Free PMC article. Review.
RECENT FINDINGS: For severe SSTIs, intensive care, source control, and broad-spectrum antimicrobials are required for the initial phase of illness. ...SUMMARY: Severe SSTIs are common and their management complex due to regional variation in predominant pathogens and an …
RECENT FINDINGS: For severe SSTIs, intensive care, source control, and broad-spectrum antimicrobials are required for the initial pha …
1,251 results