Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1845 1
1851 1
1878 1
1898 1
1912 2
1920 1
1921 1
1926 1
1927 2
1929 1
1931 1
1933 2
1934 1
1935 1
1939 1
1940 2
1941 1
1947 1
1948 5
1950 4
1951 3
1952 2
1953 7
1954 6
1955 6
1956 3
1957 7
1958 9
1959 2
1960 3
1961 7
1962 8
1963 11
1964 8
1965 9
1966 10
1967 28
1968 34
1969 23
1970 15
1971 22
1972 36
1973 33
1974 32
1975 163
1976 152
1977 152
1978 173
1979 177
1980 145
1981 168
1982 228
1983 219
1984 275
1985 295
1986 301
1987 310
1988 307
1989 434
1990 456
1991 517
1992 536
1993 583
1994 612
1995 669
1996 774
1997 786
1998 860
1999 890
2000 991
2001 1035
2002 1087
2003 1155
2004 1244
2005 1449
2006 1528
2007 1682
2008 1775
2009 1972
2010 2143
2011 2416
2012 2565
2013 2838
2014 3283
2015 3438
2016 3779
2017 4131
2018 4385
2019 4684
2020 5783
2021 6538
2022 6488
2023 6198
2024 6767
2025 9174
2026 4500

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

92,398 results

Results by year

Filters applied: . Clear all
Page 1
Critical period plasticity in local cortical circuits.
Hensch TK. Hensch TK. Nat Rev Neurosci. 2005 Nov;6(11):877-88. doi: 10.1038/nrn1787. Nat Rev Neurosci. 2005. PMID: 16261181 Review.
Neuronal circuits in the brain are shaped by experience during 'critical periods' in early postnatal life. In the primary visual cortex, this activity-dependent development is triggered by the functional maturation of local inhibitory connections and driven by a specific, …
Neuronal circuits in the brain are shaped by experience during 'critical periods' in early postnatal life. In the primary visual cort …
Critical period regulation.
Hensch TK. Hensch TK. Annu Rev Neurosci. 2004;27:549-79. doi: 10.1146/annurev.neuro.27.070203.144327. Annu Rev Neurosci. 2004. PMID: 15217343 Review.
Neuronal circuits are shaped by experience during critical periods of early postnatal life. The ability to control the timing, duration, and closure of these heightened levels of brain plasticity has recently become experimentally accessible, especially in the developing v …
Neuronal circuits are shaped by experience during critical periods of early postnatal life. The ability to control the timing, durati …
A critical period for second language acquisition: Evidence from 2/3 million English speakers.
Hartshorne JK, Tenenbaum JB, Pinker S. Hartshorne JK, et al. Cognition. 2018 Aug;177:263-277. doi: 10.1016/j.cognition.2018.04.007. Epub 2018 May 2. Cognition. 2018. PMID: 29729947 Free PMC article.
The results support the existence of a sharply-defined critical period for language acquisition, but the age of offset is much later than previously speculated. ...
The results support the existence of a sharply-defined critical period for language acquisition, but the age of offset is much …
Critical periods of brain development.
Cisneros-Franco JM, Voss P, Thomas ME, de Villers-Sidani E. Cisneros-Franco JM, et al. Handb Clin Neurol. 2020;173:75-88. doi: 10.1016/B978-0-444-64150-2.00009-5. Handb Clin Neurol. 2020. PMID: 32958196
Next, we define what constitutes a CP (Section What Are Critical Periods?) and review some of the key CPs in the visual and auditory systems (Section Key Critical Periods of Sensory Systems). We then discuss the mechanisms whereby cortical plasticity is regulated bo …
Next, we define what constitutes a CP (Section What Are Critical Periods?) and review some of the key CPs in the visual and auditory …
Critical-period plasticity in the visual cortex.
Levelt CN, Hübener M. Levelt CN, et al. Annu Rev Neurosci. 2012;35:309-30. doi: 10.1146/annurev-neuro-061010-113813. Epub 2012 Mar 29. Annu Rev Neurosci. 2012. PMID: 22462544 Review.
In many regions of the developing brain, neuronal circuits undergo defined phases of enhanced plasticity, termed critical periods. Work in the rodent visual cortex has led to important insights into the cellular and molecular mechanisms regulating the timing of the crit …
In many regions of the developing brain, neuronal circuits undergo defined phases of enhanced plasticity, termed critical periods. Wo …
Critical period revisited: impact on vision.
Morishita H, Hensch TK. Morishita H, et al. Curr Opin Neurobiol. 2008 Feb;18(1):101-7. doi: 10.1016/j.conb.2008.05.009. Epub 2008 Jun 3. Curr Opin Neurobiol. 2008. PMID: 18534841 Review.
The permanent loss of visual acuity (amblyopia) and anatomical remodeling within primary visual cortex following monocular deprivation is a classic example of critical period development from mouse to man. Recent work in rodents reveals a residual subthreshold poten …
The permanent loss of visual acuity (amblyopia) and anatomical remodeling within primary visual cortex following monocular deprivation is a …
Critical period mechanisms in developing visual cortex.
Hensch TK. Hensch TK. Curr Top Dev Biol. 2005;69:215-37. doi: 10.1016/S0070-2153(05)69008-4. Curr Top Dev Biol. 2005. PMID: 16243601 Review.
Binocular vision is shaped by experience during a critical period of early postnatal life. Loss of visual acuity following monocular deprivation is mediated by a shift of spiking output from the primary visual cortex. ...In fact, critical period plasti …
Binocular vision is shaped by experience during a critical period of early postnatal life. Loss of visual acuity following mon …
Astroglial regulation of critical period plasticity in the developing brain.
Ribot J, Breton R, Dallérac G, Rouach N. Ribot J, et al. Curr Opin Neurobiol. 2025 Oct;94:103092. doi: 10.1016/j.conb.2025.103092. Epub 2025 Aug 14. Curr Opin Neurobiol. 2025. PMID: 40816152 Free article. Review.
Astrocytes emerge as pivotal regulators of brain plasticity during critical periods (CPs) of development. Beyond their traditional roles in supporting neuronal function, astrocytes actively shape synaptic circuits maturation and remodeling during postnatal experience-depen …
Astrocytes emerge as pivotal regulators of brain plasticity during critical periods (CPs) of development. Beyond their traditional ro …
Rejuvenation of plasticity in the brain: opening the critical period.
Patton MH, Blundon JA, Zakharenko SS. Patton MH, et al. Curr Opin Neurobiol. 2019 Feb;54:83-89. doi: 10.1016/j.conb.2018.09.003. Epub 2018 Oct 2. Curr Opin Neurobiol. 2019. PMID: 30286407 Free PMC article. Review.
It has been suggested that pairing sounds with the activation of neuromodulatory circuits involved in attention reopens this critical period. Here, we review two critical period hypotheses related to neuromodulation: cortical disinhibition and thalamic …
It has been suggested that pairing sounds with the activation of neuromodulatory circuits involved in attention reopens this critical …
Autism: a "critical period" disorder?
LeBlanc JJ, Fagiolini M. LeBlanc JJ, et al. Neural Plast. 2011;2011:921680. doi: 10.1155/2011/921680. Epub 2011 Aug 3. Neural Plast. 2011. PMID: 21826280 Free PMC article. Review.
Cortical circuits in the brain are refined by experience during critical periods early in postnatal life. Critical periods are regulated by the balance of excitatory and inhibitory (E/I) neurotransmission in the brain during development. ...We propose that alteratio …
Cortical circuits in the brain are refined by experience during critical periods early in postnatal life. Critical periods are …
92,398 results
You have reached the last available page of results. Please see the User Guide for more information.