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1933 2
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1939 1
1940 2
1941 1
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1948 5
1950 4
1951 3
1952 2
1953 7
1954 6
1955 6
1956 3
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1958 9
1959 2
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1975 163
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1978 173
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2005 1449
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2009 1972
2010 2143
2011 2416
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2013 2838
2014 3283
2015 3438
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92,398 results

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Page 1
Critical period plasticity in local cortical circuits.
Hensch TK. Hensch TK. Nat Rev Neurosci. 2005 Nov;6(11):877-88. doi: 10.1038/nrn1787. Nat Rev Neurosci. 2005. PMID: 16261181 Review.
Neuronal circuits in the brain are shaped by experience during 'critical periods' in early postnatal life. In the primary visual cortex, this activity-dependent development is triggered by the functional maturation of local inhibitory connections and driven by a specific, …
Neuronal circuits in the brain are shaped by experience during 'critical periods' in early postnatal life. In the primary visual cort …
Critical period regulation.
Hensch TK. Hensch TK. Annu Rev Neurosci. 2004;27:549-79. doi: 10.1146/annurev.neuro.27.070203.144327. Annu Rev Neurosci. 2004. PMID: 15217343 Review.
Neuronal circuits are shaped by experience during critical periods of early postnatal life. The ability to control the timing, duration, and closure of these heightened levels of brain plasticity has recently become experimentally accessible, especially in the developing v …
Neuronal circuits are shaped by experience during critical periods of early postnatal life. The ability to control the timing, durati …
A critical period for second language acquisition: Evidence from 2/3 million English speakers.
Hartshorne JK, Tenenbaum JB, Pinker S. Hartshorne JK, et al. Cognition. 2018 Aug;177:263-277. doi: 10.1016/j.cognition.2018.04.007. Epub 2018 May 2. Cognition. 2018. PMID: 29729947 Free PMC article.
The results support the existence of a sharply-defined critical period for language acquisition, but the age of offset is much later than previously speculated. ...
The results support the existence of a sharply-defined critical period for language acquisition, but the age of offset is much …
Critical periods of brain development.
Cisneros-Franco JM, Voss P, Thomas ME, de Villers-Sidani E. Cisneros-Franco JM, et al. Handb Clin Neurol. 2020;173:75-88. doi: 10.1016/B978-0-444-64150-2.00009-5. Handb Clin Neurol. 2020. PMID: 32958196
Next, we define what constitutes a CP (Section What Are Critical Periods?) and review some of the key CPs in the visual and auditory systems (Section Key Critical Periods of Sensory Systems). We then discuss the mechanisms whereby cortical plasticity is regulated bo …
Next, we define what constitutes a CP (Section What Are Critical Periods?) and review some of the key CPs in the visual and auditory …
Critical-period plasticity in the visual cortex.
Levelt CN, Hübener M. Levelt CN, et al. Annu Rev Neurosci. 2012;35:309-30. doi: 10.1146/annurev-neuro-061010-113813. Epub 2012 Mar 29. Annu Rev Neurosci. 2012. PMID: 22462544 Review.
In many regions of the developing brain, neuronal circuits undergo defined phases of enhanced plasticity, termed critical periods. Work in the rodent visual cortex has led to important insights into the cellular and molecular mechanisms regulating the timing of the crit
In many regions of the developing brain, neuronal circuits undergo defined phases of enhanced plasticity, termed critical periods. Wo …
Critical period revisited: impact on vision.
Morishita H, Hensch TK. Morishita H, et al. Curr Opin Neurobiol. 2008 Feb;18(1):101-7. doi: 10.1016/j.conb.2008.05.009. Epub 2008 Jun 3. Curr Opin Neurobiol. 2008. PMID: 18534841 Review.
The permanent loss of visual acuity (amblyopia) and anatomical remodeling within primary visual cortex following monocular deprivation is a classic example of critical period development from mouse to man. Recent work in rodents reveals a residual subthreshold poten …
The permanent loss of visual acuity (amblyopia) and anatomical remodeling within primary visual cortex following monocular deprivation is a …
Critical period mechanisms in developing visual cortex.
Hensch TK. Hensch TK. Curr Top Dev Biol. 2005;69:215-37. doi: 10.1016/S0070-2153(05)69008-4. Curr Top Dev Biol. 2005. PMID: 16243601 Review.
Binocular vision is shaped by experience during a critical period of early postnatal life. Loss of visual acuity following monocular deprivation is mediated by a shift of spiking output from the primary visual cortex. ...In fact, critical period plasti …
Binocular vision is shaped by experience during a critical period of early postnatal life. Loss of visual acuity following mon …
Astroglial regulation of critical period plasticity in the developing brain.
Ribot J, Breton R, Dallérac G, Rouach N. Ribot J, et al. Curr Opin Neurobiol. 2025 Oct;94:103092. doi: 10.1016/j.conb.2025.103092. Epub 2025 Aug 14. Curr Opin Neurobiol. 2025. PMID: 40816152 Free article. Review.
Astrocytes emerge as pivotal regulators of brain plasticity during critical periods (CPs) of development. Beyond their traditional roles in supporting neuronal function, astrocytes actively shape synaptic circuits maturation and remodeling during postnatal experience-depen …
Astrocytes emerge as pivotal regulators of brain plasticity during critical periods (CPs) of development. Beyond their traditional ro …
Rejuvenation of plasticity in the brain: opening the critical period.
Patton MH, Blundon JA, Zakharenko SS. Patton MH, et al. Curr Opin Neurobiol. 2019 Feb;54:83-89. doi: 10.1016/j.conb.2018.09.003. Epub 2018 Oct 2. Curr Opin Neurobiol. 2019. PMID: 30286407 Free PMC article. Review.
It has been suggested that pairing sounds with the activation of neuromodulatory circuits involved in attention reopens this critical period. Here, we review two critical period hypotheses related to neuromodulation: cortical disinhibition and thalamic …
It has been suggested that pairing sounds with the activation of neuromodulatory circuits involved in attention reopens this critical
Autism: a "critical period" disorder?
LeBlanc JJ, Fagiolini M. LeBlanc JJ, et al. Neural Plast. 2011;2011:921680. doi: 10.1155/2011/921680. Epub 2011 Aug 3. Neural Plast. 2011. PMID: 21826280 Free PMC article. Review.
Cortical circuits in the brain are refined by experience during critical periods early in postnatal life. Critical periods are regulated by the balance of excitatory and inhibitory (E/I) neurotransmission in the brain during development. ...We propose that alteratio …
Cortical circuits in the brain are refined by experience during critical periods early in postnatal life. Critical periods are …
92,398 results
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