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2001 1
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2005 8
2006 15
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2009 34
2010 46
2011 69
2012 81
2013 107
2014 182
2015 167
2016 220
2017 205
2018 214
2019 305
2020 270
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1,756 results
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The Microbiome in Crohn's Disease: Role in Pathogenesis and Role of Microbiome Replacement Therapies.
Khanna S, Raffals LE. Khanna S, et al. Gastroenterol Clin North Am. 2017 Sep;46(3):481-492. doi: 10.1016/j.gtc.2017.05.004. Epub 2017 Jul 19. Gastroenterol Clin North Am. 2017. PMID: 28838410 Review.
Individuals with a genetic predisposition to Crohn's disease develop aberrant immune responses to environmental triggers. The gastrointestinal microbiota is increasingly recognized to play an important role in the development of Crohn's disease. …
Individuals with a genetic predisposition to Crohn's disease develop aberrant immune responses to environmental triggers. The …
The treatment-naive microbiome in new-onset Crohn's disease.
Gevers D, Kugathasan S, Denson LA, Vázquez-Baeza Y, Van Treuren W, Ren B, Schwager E, Knights D, Song SJ, Yassour M, Morgan XC, Kostic AD, Luo C, González A, McDonald D, Haberman Y, Walters T, Baker S, Rosh J, Stephens M, Heyman M, Markowitz J, Baldassano R, Griffiths A, Sylvester F, Mack D, Kim S, Crandall W, Hyams J, Huttenhower C, Knight R, Xavier RJ. Gevers D, et al. Cell Host Microbe. 2014 Mar 12;15(3):382-392. doi: 10.1016/j.chom.2014.02.005. Cell Host Microbe. 2014. PMID: 24629344 Free PMC article.
Inflammatory bowel diseases (IBDs), including Crohn's disease (CD), are genetically linked to host pathways that implicate an underlying role for aberrant immune responses to intestinal microbiota. However, patterns of gut microbiome dysbiosis in IBD p …
Inflammatory bowel diseases (IBDs), including Crohn's disease (CD), are genetically linked to host pathways that implicate an …
The Impact of Exclusive Enteral Nutrition (EEN) on the Gut Microbiome in Crohn's Disease: A Review.
MacLellan A, Moore-Connors J, Grant S, Cahill L, Langille MGI, Van Limbergen J. MacLellan A, et al. Nutrients. 2017 May 1;9(5):447. doi: 10.3390/nu9050447. Nutrients. 2017. PMID: 28468301 Free PMC article. Review.
Crohn's disease (CD), a form of inflammatory bowel disease (IBD), is thought to arise from a complex interaction of genetics, the gut microbiome, and environmental factors, such as diet. ...While the mechanism of action of EEN is not clear, EEN is known to ca …
Crohn's disease (CD), a form of inflammatory bowel disease (IBD), is thought to arise from a complex interaction of genetics, …
A Microbiome Foundation for the Study of Crohn's Disease.
Gevers D, Kugathasan S, Knights D, Kostic AD, Knight R, Xavier RJ. Gevers D, et al. Cell Host Microbe. 2017 Mar 8;21(3):301-304. doi: 10.1016/j.chom.2017.02.012. Cell Host Microbe. 2017. PMID: 28279336 Free PMC article.
Our 2014 study published in Cell Host & Microbe, "The Treatment-Naive Microbiome in New-Onset Crohn's Disease," was designed to improve our understanding of the microbiome's role in Crohn's disease by studying a unique, well-su …
Our 2014 study published in Cell Host & Microbe, "The Treatment-Naive Microbiome in New-Onset Crohn's Disease," was …
Inflammation, Antibiotics, and Diet as Environmental Stressors of the Gut Microbiome in Pediatric Crohn's Disease.
Lewis JD, Chen EZ, Baldassano RN, Otley AR, Griffiths AM, Lee D, Bittinger K, Bailey A, Friedman ES, Hoffmann C, Albenberg L, Sinha R, Compher C, Gilroy E, Nessel L, Grant A, Chehoud C, Li H, Wu GD, Bushman FD. Lewis JD, et al. Cell Host Microbe. 2015 Oct 14;18(4):489-500. doi: 10.1016/j.chom.2015.09.008. Cell Host Microbe. 2015. PMID: 26468751 Free PMC article.
Abnormal composition of intestinal bacteria--"dysbiosis"-is characteristic of Crohn's disease. Disease treatments include dietary changes and immunosuppressive anti-TNFα antibodies as well as ancillary antibiotic therapy, but their effects on microbiota compo …
Abnormal composition of intestinal bacteria--"dysbiosis"-is characteristic of Crohn's disease. Disease treatments include diet …
Treatment of Active Crohn's Disease With an Ordinary Food-based Diet That Replicates Exclusive Enteral Nutrition.
Svolos V, Hansen R, Nichols B, Quince C, Ijaz UZ, Papadopoulou RT, Edwards CA, Watson D, Alghamdi A, Brejnrod A, Ansalone C, Duncan H, Gervais L, Tayler R, Salmond J, Bolognini D, Klopfleisch R, Gaya DR, Milling S, Russell RK, Gerasimidis K. Svolos V, et al. Gastroenterology. 2019 Apr;156(5):1354-1367.e6. doi: 10.1053/j.gastro.2018.12.002. Epub 2018 Dec 11. Gastroenterology. 2019. PMID: 30550821 Free article. Clinical Trial.
BACKGROUND & AIMS: Exclusive enteral nutrition (EEN) is the only established dietary treatment for Crohn's disease (CD), but its acceptability is limited. ...CONCLUSION: CD-TREAT replicates EEN changes in the microbiome, decreases gut inflammation, is wel …
BACKGROUND & AIMS: Exclusive enteral nutrition (EEN) is the only established dietary treatment for Crohn's disease (CD), b …
Probiotics and prebiotics in Crohn's disease therapies.
Lichtenstein L, Avni-Biron I, Ben-Bassat O. Lichtenstein L, et al. Best Pract Res Clin Gastroenterol. 2016 Feb;30(1):81-8. doi: 10.1016/j.bpg.2016.02.002. Epub 2016 Feb 9. Best Pract Res Clin Gastroenterol. 2016. PMID: 27048899 Review.
Therapeutic manipulation of gut microbiota has proven valuable in the management of ulcerative colitis and pouchitis. Despite some similarities among the various inflammatory bowel conditions, the probiotics investigated thus far seem to confer little benefit in Crohn …
Therapeutic manipulation of gut microbiota has proven valuable in the management of ulcerative colitis and pouchitis. Despite some si …
Enteral Nutrition in the Management of Pediatric and Adult Crohn's Disease.
Hansen T, Duerksen DR. Hansen T, et al. Nutrients. 2018 Apr 26;10(5):537. doi: 10.3390/nu10050537. Nutrients. 2018. PMID: 29701656 Free PMC article. Review.
Genetic and environmental factors are thought to profoundly influence the pathophysiology of Crohn’s disease (CD). Changes in dietary and hygiene patterns affect the interactions between the immune system and environment. ...Overall, EEN is an established …
Genetic and environmental factors are thought to profoundly influence the pathophysiology of Crohn’s disease (CD). C …
A microbial signature for Crohn's disease.
Pascal V, Pozuelo M, Borruel N, Casellas F, Campos D, Santiago A, Martinez X, Varela E, Sarrabayrouse G, Machiels K, Vermeire S, Sokol H, Guarner F, Manichanh C. Pascal V, et al. Gut. 2017 May;66(5):813-822. doi: 10.1136/gutjnl-2016-313235. Epub 2017 Feb 7. Gut. 2017. PMID: 28179361 Free PMC article.
OBJECTIVE: A decade of microbiome studies has linked IBD to an alteration in the gut microbial community of genetically predisposed subjects. ...Here, we aimed to compare the faecal microbiome of CD with patients having UC and with non-IBD subjects in a longitudinal …
OBJECTIVE: A decade of microbiome studies has linked IBD to an alteration in the gut microbial community of genetically predisposed s …
Gut microbiome structure and metabolic activity in inflammatory bowel disease.
Franzosa EA, Sirota-Madi A, Avila-Pacheco J, Fornelos N, Haiser HJ, Reinker S, Vatanen T, Hall AB, Mallick H, McIver LJ, Sauk JS, Wilson RG, Stevens BW, Scott JM, Pierce K, Deik AA, Bullock K, Imhann F, Porter JA, Zhernakova A, Fu J, Weersma RK, Wijmenga C, Clish CB, Vlamakis H, Huttenhower C, Xavier RJ. Franzosa EA, et al. Nat Microbiol. 2019 Feb;4(2):293-305. doi: 10.1038/s41564-018-0306-4. Epub 2018 Dec 10. Nat Microbiol. 2019. PMID: 30531976 Free PMC article.
The inflammatory bowel diseases (IBDs), which include Crohn's disease (CD) and ulcerative colitis (UC), are multifactorial chronic conditions of the gastrointestinal tract. While IBD has been associated with dramatic changes in the gut microbiota, changes in …
The inflammatory bowel diseases (IBDs), which include Crohn's disease (CD) and ulcerative colitis (UC), are multifactorial chr …
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