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79 results

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Page 1
Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration.
Lindemans CA, Calafiore M, Mertelsmann AM, O'Connor MH, Dudakov JA, Jenq RR, Velardi E, Young LF, Smith OM, Lawrence G, Ivanov JA, Fu YY, Takashima S, Hua G, Martin ML, O'Rourke KP, Lo YH, Mokry M, Romera-Hernandez M, Cupedo T, Dow L, Nieuwenhuis EE, Shroyer NF, Liu C, Kolesnick R, van den Brink MRM, Hanash AM. Lindemans CA, et al. Among authors: cupedo t. Nature. 2015 Dec 24;528(7583):560-564. doi: 10.1038/nature16460. Epub 2015 Dec 9. Nature. 2015. PMID: 26649819 Free PMC article.
Bone marrow inflammation in haematological malignancies.
de Jong MME, Chen L, Raaijmakers MHGP, Cupedo T. de Jong MME, et al. Among authors: cupedo t. Nat Rev Immunol. 2024 Aug;24(8):543-558. doi: 10.1038/s41577-024-01003-x. Epub 2024 Mar 15. Nat Rev Immunol. 2024. PMID: 38491073 Review.
The multiple myeloma microenvironment is defined by an inflammatory stromal cell landscape.
de Jong MME, Kellermayer Z, Papazian N, Tahri S, Hofste Op Bruinink D, Hoogenboezem R, Sanders MA, van de Woestijne PC, Bos PK, Khandanpour C, Vermeulen J, Moreau P, van Duin M, Broijl A, Sonneveld P, Cupedo T. de Jong MME, et al. Among authors: cupedo t. Nat Immunol. 2021 Jun;22(6):769-780. doi: 10.1038/s41590-021-00931-3. Epub 2021 May 20. Nat Immunol. 2021. PMID: 34017122 Clinical Trial.
An IL-1β-driven neutrophil-stromal cell axis fosters a BAFF-rich protumor microenvironment in individuals with multiple myeloma.
de Jong MME, Fokkema C, Papazian N, Czeti Á, Appelman MK, Vermeulen M, van Heusden T, Hoogenboezem RM, van Beek G, Tahri S, Sanders MA, van de Woestijne PC, Gay F, Moreau P, Büttner-Herold M, Bruns H, van Duin M, Broijl A, Sonneveld P, Cupedo T. de Jong MME, et al. Among authors: cupedo t. Nat Immunol. 2024 May;25(5):820-833. doi: 10.1038/s41590-024-01808-x. Epub 2024 Apr 10. Nat Immunol. 2024. PMID: 38600356
Inhibition of MICA and MICB shedding enhances memory-like NK-cell-mediated cytotoxicity against multiple myeloma.
Tahri S, Piccinelli S, Su NK, Lampe L, Dong H, Vergara Cadavid J, Boiarsky R, Papazian N, Lightbody ED, Cao A, Alberge JB, Ferrari de Andrade L, Rahmat M, Shen Y, Blanco Fernández L, Zabaleta A, Günther A, Getz G, Sonneveld P, Cupedo T, Wucherpfennig KW, Ghobrial IM, Romee R. Tahri S, et al. Among authors: cupedo t. Blood Adv. 2024 Oct 22;8(20):5365-5370. doi: 10.1182/bloodadvances.2023010869. Blood Adv. 2024. PMID: 39106432 Free PMC article. No abstract available.
Aberrant single-cell phenotype and clinical implications of genotypically defined polyclonal plasma cells in myeloma.
Da Vià MC, Lazzaroni F, Matera A, Marella A, Maeda A, De Magistris C, Pettine L, Solimando AG, Desantis V, Peretti GM, Mangiavini L, Giorgino R, Fabris S, Pioggia S, Marchetti A, Barbieri M, Lonati S, Cattaneo A, Tornese M, Scopetti M, Calvi E, Latifinavid N, Castellano G, Torricelli F, Neri A, Fokkema C, Cupedo T, Lionetti M, Passamonti F, Bolli N. Da Vià MC, et al. Among authors: cupedo t. Blood. 2025 Jun 26;145(26):3124-3138. doi: 10.1182/blood.2024025643. Blood. 2025. PMID: 40009503 Free article.
The bone marrow NK-cell profile predicts MRD negativity in patients with multiple myeloma treated with daratumumab-based therapy.
Korst CLBM, Tahri S, Duetz C, Bruins WSC, de Jonge AV, de Jong ME, Fokkema C, Smits F, Groen K, Verkleij CPM, Frerichs KA, Papazian N, van Duin M, van Beek G, Hoogenboezem R, Baardemans T, Dal Collo G, Stoetman ECG, Cosovic M, Twickler I, Rentenaar R, Eken M, Homan-Weert PM, Saraci E, D'Agostino M, van der Velden VHJ, Sanders MA, Gay F, Broijl A, Moreau P, Sonneveld P, Zweegman S, Mutis T, Cupedo T, van de Donk NWCJ. Korst CLBM, et al. Among authors: cupedo t. Blood. 2025 Jun 19;145(25):3007-3014. doi: 10.1182/blood.2024026455. Blood. 2025. PMID: 40019438
A Single-Cell Taxonomy Predicts Inflammatory Niche Remodeling to Drive Tissue Failure and Outcome in Human AML.
Chen L, Pronk E, van Dijk C, Bian Y, Feyen J, van Tienhoven T, Yildirim M, Pisterzi P, de Jong MME, Bastidas A, Hoogenboezem RM, Wevers C, Bindels EM, Löwenberg B, Cupedo T, Sanders MA, Raaijmakers MHGP. Chen L, et al. Among authors: cupedo t. Blood Cancer Discov. 2023 Sep 1;4(5):394-417. doi: 10.1158/2643-3230.BCD-23-0043. Blood Cancer Discov. 2023. PMID: 37470778 Free PMC article.
79 results