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Curcumin and chronic kidney disease (CKD): major mode of action through stimulating endogenous intestinal alkaline phosphatase.
Ghosh SS, Gehr TW, Ghosh S. Ghosh SS, et al. Molecules. 2014 Dec 2;19(12):20139-56. doi: 10.3390/molecules191220139. Molecules. 2014. PMID: 25474287 Free PMC article. Review.
This review will focus on the clinically relevant inflammatory molecules that play a role in CKD and associated diseases. Various enzymes, transcription factors, growth factors modulate production and action of inflammatory molecules; curcumin can blunt the generati …
This review will focus on the clinically relevant inflammatory molecules that play a role in CKD and associated diseases. Various enz …
Curcumin ameliorates CKD-induced mitochondrial dysfunction and oxidative stress through inhibiting GSK-3beta activity.
Wang D, Yang Y, Zou X, Zheng Z, Zhang J. Wang D, et al. J Nutr Biochem. 2020 Sep;83:108404. doi: 10.1016/j.jnutbio.2020.108404. Epub 2020 May 3. J Nutr Biochem. 2020. PMID: 32531667 Free article.
The aim of this study was to investigate whether curcumin could improve chronic kidney disease (CKD)-induced muscle atrophy and mitochondrial dysfunction by inhibiting glycogen synthase kinase-3beta (GSK-3beta) activity. The sham and CKD mice were fed either …
The aim of this study was to investigate whether curcumin could improve chronic kidney disease (CKD)-induced muscle atrophy an …
Curcumin relieved cisplatin-induced kidney inflammation through inhibiting Mincle-maintained M1 macrophage phenotype.
Tan RZ, Liu J, Zhang YY, Wang HL, Li JC, Liu YH, Zhong X, Zhang YW, Yan Y, Lan HY, Wang L. Tan RZ, et al. Phytomedicine. 2019 Jan;52:284-294. doi: 10.1016/j.phymed.2018.09.210. Epub 2018 Sep 25. Phytomedicine. 2019. PMID: 30599909
BACKGROUND: Acute kidney injury (AKI) is a common kidney disease with a high risk of death and can develop into chronic kidney disease (CKD) and renal failure eventually. Curcumin, an herbal supplement, has been reported exhibiting a renoprotective role in AKI. ...I …
BACKGROUND: Acute kidney injury (AKI) is a common kidney disease with a high risk of death and can develop into chronic kidney disease (C
Curcumin Ameliorates Kidney Function and Oxidative Stress in Experimental Chronic Kidney Disease.
Ali BH, Al-Salam S, Al Suleimani Y, Al Kalbani J, Al Bahlani S, Ashique M, Manoj P, Al Dhahli B, Al Abri N, Naser HT, Yasin J, Nemmar A, Al Za'abi M, Hartmann C, Schupp N. Ali BH, et al. Basic Clin Pharmacol Toxicol. 2018 Jan;122(1):65-73. doi: 10.1111/bcpt.12817. Epub 2017 Jul 10. Basic Clin Pharmacol Toxicol. 2018. PMID: 28561324 Free article.
Rats were treated for 5 weeks with adenine to induce CKD-like renal damage and combined with three doses of curcumin. ...In conclusion, curcumin exhibits salutary effects against adenine-induced CKD in rats by reducing inflammation and oxidative stress …
Rats were treated for 5 weeks with adenine to induce CKD-like renal damage and combined with three doses of curcumin. ...In co …
Curcumin Attenuates Both Acute and Chronic Immune Nephritis.
Wu T, Marakkath B, Ye Y, Khobahy E, Yan M, Hutcheson J, Zhu J, Zhou X, Mohan C. Wu T, et al. Int J Mol Sci. 2020 Mar 4;21(5):1745. doi: 10.3390/ijms21051745. Int J Mol Sci. 2020. PMID: 32143311 Free PMC article.
The aim of the present study is to investigate the therapeutic effects of curcumin on immune-mediated renal disease in an anti-glomerular basement membrane (GBM) model (representing acute kidney Injury, AKI) and murine lupus model (representing chronic kidney disease, C
The aim of the present study is to investigate the therapeutic effects of curcumin on immune-mediated renal disease in an anti-glomer …
Nutrients, Nutraceuticals, and Xenobiotics Affecting Renal Health.
Cosola C, Sabatino A, di Bari I, Fiaccadori E, Gesualdo L. Cosola C, et al. Nutrients. 2018 Jun 23;10(7):808. doi: 10.3390/nu10070808. Nutrients. 2018. PMID: 29937486 Free PMC article. Review.
Chronic kidney disease (CKD) affects 8-16% of the population worldwide. In developed countries, the most important risk factors for CKD are diabetes, hypertension, and obesity, calling into question the importance of educating and acting on lifestyles and nutrition. …
Chronic kidney disease (CKD) affects 8-16% of the population worldwide. In developed countries, the most important risk factors for …
Curcumin attenuates angiotensin II-induced podocyte injury and apoptosis by inhibiting endoplasmic reticulum stress.
Yu N, Yang L, Ling L, Liu Y, Yu Y, Wu Q, Gu Y, Niu J. Yu N, et al. FEBS Open Bio. 2020 Oct;10(10):1957-1966. doi: 10.1002/2211-5463.12946. Epub 2020 Aug 28. FEBS Open Bio. 2020. PMID: 32770719 Free PMC article.
Curcumin is a hydrophobic polyphenolic compound extracted from turmeric. Increasing evidence demonstrates that curcumin has a protective effect on the kidneys in CKD. However, the mechanisms mediating this protective effect remain unclear. ...
Curcumin is a hydrophobic polyphenolic compound extracted from turmeric. Increasing evidence demonstrates that curcumin has a
The effect of curcumin in prevention of contrast nephropathy following coronary angiography or angioplasty in CKD patients.
Hami M, Bigdeli A, Khameneh Bagheri R, Rajabi O, Salehi M, Zahedi Avval F. Hami M, et al. Iran J Kidney Dis. 2019 Sep;13(5):304-309. Iran J Kidney Dis. 2019. PMID: 31705746 Free article. Clinical Trial.
It is appeared that the oxidative stress is the main mechanism of contrast nephropathy. Curcumin is suggested as an herbal antioxidant agent, so we decided to assess the effect of curcumin in preventing of this complication in patients with underlying chronic kidney …
It is appeared that the oxidative stress is the main mechanism of contrast nephropathy. Curcumin is suggested as an herbal antioxidan …
Dietary Components That May Influence the Disturbed Gut Microbiota in Chronic Kidney Disease.
Mafra D, Borges N, Alvarenga L, Esgalhado M, Cardozo L, Lindholm B, Stenvinkel P. Mafra D, et al. Nutrients. 2019 Feb 27;11(3):496. doi: 10.3390/nu11030496. Nutrients. 2019. PMID: 30818761 Free PMC article. Review.
Different nutritional strategies have been proposed to modulate gut microbiota, and could potentially be used to reduce dysbiosis in CKD. Nutrients like proteins, fibers, probiotics, and synbiotics are important determinants of the composition of gut microbiota and specifi …
Different nutritional strategies have been proposed to modulate gut microbiota, and could potentially be used to reduce dysbiosis in CKD
Impact of curcumin supplementation on expression of inflammatory transcription factors in hemodialysis patients: A pilot randomized, double-blind, controlled study.
Alvarenga L, Salarolli R, Cardozo LFMF, Santos RS, de Brito JS, Kemp JA, Reis D, de Paiva BR, Stenvinkel P, Lindholm B, Fouque D, Mafra D. Alvarenga L, et al. Clin Nutr. 2020 Dec;39(12):3594-3600. doi: 10.1016/j.clnu.2020.03.007. Epub 2020 Mar 13. Clin Nutr. 2020. PMID: 32204978 Clinical Trial.
Our aim was to evaluate the effects of curcumin juice on the expression of inflammatory transcription factors in hemodialysis (HD) patients. ...There was no change in the other evaluated markers. CONCLUSION: Three months treatment with curcumin in CKD patient …
Our aim was to evaluate the effects of curcumin juice on the expression of inflammatory transcription factors in hemodialysis (HD) pa …
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