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A diet enriched with curcumin impairs newly acquired and reactivated fear memories.
Monsey MS, Gerhard DM, Boyle LM, Briones MA, Seligsohn M, Schafe GE. Monsey MS, et al. Neuropsychopharmacology. 2015 Mar 13;40(5):1278-88. doi: 10.1038/npp.2014.315. Neuropsychopharmacology. 2015. PMID: 25430781 Free PMC article.
Next, we show that dietary curcumin impairs the 'reconsolidation' of a recently formed auditory Pavlovian fear memory; fear memory retrieval (reactivation) and postreactivation (PR)-STM are intact, whereas PR-LTM is significantly impaired. ...Fu …
Next, we show that dietary curcumin impairs the 'reconsolidation' of a recently formed auditory Pavlovian fear memory; …
Curcumin improves D-galactose and normal-aging associated memory impairment in mice: In vivo and in silico-based studies.
Rahman MA, Shuvo AA, Bepari AK, Hasan Apu M, Shill MC, Hossain M, Uddin M, Islam MR, Bakshi MK, Hasan J, Rahman A, Rahman GMS, Reza HM. Rahman MA, et al. PLoS One. 2022 Jun 29;17(6):e0270123. doi: 10.1371/journal.pone.0270123. eCollection 2022. PLoS One. 2022. PMID: 35767571 Free PMC article.
Retention and freezing memories were assessed by passive avoidance (PA) and contextual fear conditioning (CFC). ...In silico studies revealed favorable binding energies of curcumin with GSTA1, GSTO1, KEAP1, BACE1, and MAOA. Curcumin improves retention …
Retention and freezing memories were assessed by passive avoidance (PA) and contextual fear conditioning (CFC). ...In silico s …
Combination of epigallocatechin 3 gallate and curcumin improves D-galactose and normal-aging associated memory impairment in mice.
Rahman MA, Shuvo AA, Apu MMH, Bhakta MR, Islam F, Rahman MA, Islam MR, Reza HM. Rahman MA, et al. Sci Rep. 2023 Aug 4;13(1):12681. doi: 10.1038/s41598-023-39919-4. Sci Rep. 2023. PMID: 37542120 Free PMC article.
Previously, we observed curcumin improves aging-associated memory impairment in D-galactose (D-gal) and normal-aged (NA) mice. ...EGCG and curcumin combination could serve as a better choice in managing aging-related memory disorders....
Previously, we observed curcumin improves aging-associated memory impairment in D-galactose (D-gal) and normal-aged (NA) mice. …
Assessment of diets containing curcumin, epigallocatechin-3-gallate, docosahexaenoic acid and α-lipoic acid on amyloid load and inflammation in a male transgenic mouse model of Alzheimer's disease: Are combinations more effective?
Sharman MJ, Gyengesi E, Liang H, Chatterjee P, Karl T, Li QX, Wenk MR, Halliwell B, Martins RN, Münch G. Sharman MJ, et al. Neurobiol Dis. 2019 Apr;124:505-519. doi: 10.1016/j.nbd.2018.11.026. Epub 2019 Jan 2. Neurobiol Dis. 2019. PMID: 30610916
Increasingly, evidence is accumulating pointing at a protective role of a healthy diet at decreasing the risk of Alzheimer's disease. To test the effectiveness of nutritional components, the following food-derived compounds: curcumin alone (curcumin), curc …
Increasingly, evidence is accumulating pointing at a protective role of a healthy diet at decreasing the risk of Alzheimer's disease. …
Highly stabilized curcumin nanoparticles tested in an in vitro blood-brain barrier model and in Alzheimer's disease Tg2576 mice.
Cheng KK, Yeung CF, Ho SW, Chow SF, Chow AH, Baum L. Cheng KK, et al. AAPS J. 2013 Apr;15(2):324-36. doi: 10.1208/s12248-012-9444-4. Epub 2012 Dec 11. AAPS J. 2013. PMID: 23229335 Free PMC article.
Before and after treatment, memory was measured by radial arm maze and contextual fear conditioning tests. Nanocurcumin produced significantly (p=0.04) better cue memory in the contextual fear conditioning test than placebo and tendencies toward better …
Before and after treatment, memory was measured by radial arm maze and contextual fear conditioning tests. Nanocurcumin produc …
Pre-administration of curcumin prevents neonatal sevoflurane exposure-induced neurobehavioral abnormalities in mice.
Ji MH, Qiu LL, Yang JJ, Zhang H, Sun XR, Zhu SH, Li WY, Yang JJ. Ji MH, et al. Neurotoxicology. 2015 Jan;46:155-64. doi: 10.1016/j.neuro.2014.11.003. Epub 2014 Nov 15. Neurotoxicology. 2015. PMID: 25447320
Cognitive functions were evaluated by open field, Morris water maze, and fear conditioning tests on P61, P63-69, and P77-78, respectively. ...Our results showed that repeated neonatal sevoflurane exposure led to significant cognitive impairment later in life, which was ass …
Cognitive functions were evaluated by open field, Morris water maze, and fear conditioning tests on P61, P63-69, and P77-78, respecti …
The central role of heat shock factor 1 in synaptic fidelity and memory consolidation.
Hooper PL, Durham HD, Török Z, Hooper PL, Crul T, Vígh L. Hooper PL, et al. Cell Stress Chaperones. 2016 Sep;21(5):745-53. doi: 10.1007/s12192-016-0709-1. Epub 2016 Jun 9. Cell Stress Chaperones. 2016. PMID: 27283588 Free PMC article.
Networks of neuronal synapses are the fundamental basis for making and retaining memory. Reduced synapse number and quality correlates with loss of memory in dementia. Heat shock factor 1 (HSF1), the major transcription factor regulating expression of heat shock gen …
Networks of neuronal synapses are the fundamental basis for making and retaining memory. Reduced synapse number and quality correlate …