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Curcumin for neuropsychiatric disorders: a review of in vitro, animal and human studies.
Lopresti AL. Lopresti AL. J Psychopharmacol. 2017 Mar;31(3):287-302. doi: 10.1177/0269881116686883. Epub 2017 Jan 30. J Psychopharmacol. 2017. PMID: 28135888 Review.
In this systematic review, in vitro, animal, and human studies investigating the potential of curcumin as a treatment for neuropsychiatric disorders such as major depressive disorder, post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), bipolar
In this systematic review, in vitro, animal, and human studies investigating the potential of curcumin as a treatment for neuropsychi …
Curcumin in depressive disorders: An overview of potential mechanisms, preclinical and clinical findings.
Kaufmann FN, Gazal M, Bastos CR, Kaster MP, Ghisleni G. Kaufmann FN, et al. Eur J Pharmacol. 2016 Aug 5;784:192-8. doi: 10.1016/j.ejphar.2016.05.026. Epub 2016 May 24. Eur J Pharmacol. 2016. PMID: 27235294 Review.
Most literature data focused on the potential of curcumin to counteract behavioral and neurochemical alterations in preclinical models of depression. ...Despite the limited number of reports, preclinical models investigated the potential role for curcumin in anxiety …
Most literature data focused on the potential of curcumin to counteract behavioral and neurochemical alterations in preclinical model …
Is there a role for curcumin in the treatment of bipolar disorder?
Brietzke E, Mansur RB, Zugman A, Carvalho AF, Macêdo DS, Cha DS, Abílio VC, McIntyre RS. Brietzke E, et al. Med Hypotheses. 2013 May;80(5):606-12. doi: 10.1016/j.mehy.2013.02.001. Epub 2013 Feb 26. Med Hypotheses. 2013. PMID: 23484676 Free article. Review.
Curcumin putative targets, known based on studies of diverse central nervous system disorders other than bipolar disorders (BD) include several proteins currently implicated in the pathophysiology of BD. ...Herein, we review previous studies on the anti-inflammatory
Curcumin putative targets, known based on studies of diverse central nervous system disorders other than bipolar disorders (BD
Putative neuroprotective pharmacotherapies to target the staged progression of mental illness.
Robertson OD, Coronado NG, Sethi R, Berk M, Dodd S. Robertson OD, et al. Early Interv Psychiatry. 2019 Oct;13(5):1032-1049. doi: 10.1111/eip.12775. Epub 2019 Jan 28. Early Interv Psychiatry. 2019. PMID: 30690898 Review.
AIM: Neuropsychiatric disorders including depression, bipolar and schizophrenia frequently exhibit a neuroprogressive course from prodrome to chronicity. ...Agents include: the psychotropic medications lithium, second generation antipsychotics and antidepressants; other ph …
AIM: Neuropsychiatric disorders including depression, bipolar and schizophrenia frequently exhibit a neuroprogressive course from pro …
Ameliorative Effect of Curcumin on Olanzapine-induced Obesity in Sprague-Dawley Rats.
Parasuraman S, Zhen KM, Banik U, Christapher PV. Parasuraman S, et al. Pharmacognosy Res. 2017 Jul-Sep;9(3):247-252. doi: 10.4103/pr.pr_8_17. Pharmacognosy Res. 2017. PMID: 28827965 Free PMC article.
The effect of curcumin on olanzapine-induced body weight gain is not comparable with that of betahistine. CONCLUSION: This study has shown metabolic alteration effect of curcumin on olanzapine, an antipsychotic drug, treated SD rats. SUMMARY: Olanzapine is an atypic …
The effect of curcumin on olanzapine-induced body weight gain is not comparable with that of betahistine. CONCLUSION: This study has …
Curcumin Protects β-Lactoglobulin Fibril Formation and Fibril-Induced Neurotoxicity in PC12 Cells.
Mazaheri M, Moosavi-Movahedi AA, Saboury AA, Khodagholi F, Shaerzadeh F, Sheibani N. Mazaheri M, et al. PLoS One. 2015 Jul 17;10(7):e0133206. doi: 10.1371/journal.pone.0133206. eCollection 2015. PLoS One. 2015. PMID: 26186474 Free PMC article.
The cell viability, cell body area, average neurite length, neurite width, number of primary neurites, percent of bipolar cells and node/primary neurite ratios were used to assess the growth and complexity of PC12 cells exposed to different form of β-Lg fibrils. ...However …
The cell viability, cell body area, average neurite length, neurite width, number of primary neurites, percent of bipolar cells and n …
Inflamed moods: a review of the interactions between inflammation and mood disorders.
Rosenblat JD, Cha DS, Mansur RB, McIntyre RS. Rosenblat JD, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2014 Aug 4;53:23-34. doi: 10.1016/j.pnpbp.2014.01.013. Epub 2014 Jan 25. Prog Neuropsychopharmacol Biol Psychiatry. 2014. PMID: 24468642 Review.
Indeed, elevated levels of pro-inflammatory cytokines have been repeatedly demonstrated in both major depressive disorder (MDD) and bipolar disorder (BD) patients. ...Anti-inflammatory agents, such as acetyl-salicylic acid (ASA), celecoxib, anti-TNF-α agents, minocycline, …
Indeed, elevated levels of pro-inflammatory cytokines have been repeatedly demonstrated in both major depressive disorder (MDD) and bipol
Synthetic and natural inhibitors of phospholipases A2: their importance for understanding and treatment of neurological disorders.
Ong WY, Farooqui T, Kokotos G, Farooqui AA. Ong WY, et al. ACS Chem Neurosci. 2015 Jun 17;6(6):814-31. doi: 10.1021/acschemneuro.5b00073. Epub 2015 May 1. ACS Chem Neurosci. 2015. PMID: 25891385 Review.
Neurological disorders including excitotoxicity; traumatic nerve and brain injury; cerebral ischemia; Alzheimer's disease; Parkinson's disease; multiple sclerosis; experimental allergic encephalitis; pain; depression; bipolar disorder; schizophrenia; and auti …
Neurological disorders including excitotoxicity; traumatic nerve and brain injury; cerebral ischemia; Alzheimer's disease; Parkinson' …
Neuroprotective and antioxidant effects of curcumin in a ketamine-induced model of mania in rats.
Gazal M, Valente MR, Acosta BA, Kaufmann FN, Braganhol E, Lencina CL, Stefanello FM, Ghisleni G, Kaster MP. Gazal M, et al. Eur J Pharmacol. 2014 Feb 5;724:132-9. doi: 10.1016/j.ejphar.2013.12.028. Epub 2013 Dec 30. Eur J Pharmacol. 2014. PMID: 24384407
Bipolar disorder (BD) is a chronic and debilitating illness characterized by recurrent manic and depressive episodes. Our research investigates the protective effects of curcumin, the main curcuminoid of the Indian spice turmeric, in a model of mania induced by keta
Bipolar disorder (BD) is a chronic and debilitating illness characterized by recurrent manic and depressive episodes. Our research in
Role of IP3 Receptors in Shaping the Carotid Chemoreceptor Response to Hypoxia But Not to Hypercapnia in the Rat Carotid Body: An Evidence Review.
Mokashi A, Roy A, Baby SM, Mulligan EM, Lahiri S, Di Giulio C, Pokorski M. Mokashi A, et al. Adv Exp Med Biol. 2020 Aug 8. doi: 10.1007/5584_2020_561. Online ahead of print. Adv Exp Med Biol. 2020. PMID: 32767266
[Ca(2+)](c) changes were measured using cellular Ca(2+)-sensitive fluorescent probes, and carotid sinus nerve (CSN) sensory discharge was recorded with bipolar electrodes in in vitro perfused-superfused rat carotid body preparations. The cell-permeant, 2-amino-ethoxy-diphe …
[Ca(2+)](c) changes were measured using cellular Ca(2+)-sensitive fluorescent probes, and carotid sinus nerve (CSN) sensory discharge was re …
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