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Is there a role for curcumin in the treatment of bipolar disorder?
Brietzke E, Mansur RB, Zugman A, Carvalho AF, Macêdo DS, Cha DS, Abílio VC, McIntyre RS. Brietzke E, et al. Med Hypotheses. 2013 May;80(5):606-12. doi: 10.1016/j.mehy.2013.02.001. Epub 2013 Feb 26. Med Hypotheses. 2013. PMID: 23484676 Free article. Review.
Curcumin putative targets, known based on studies of diverse central nervous system disorders other than bipolar disorders (BD) include several proteins currently implicated in the pathophysiology of BD. ...Herein, we review previous studies on the anti-inflammatory …
Curcumin putative targets, known based on studies of diverse central nervous system disorders other than bipolar disorders (BD …
Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety Treatments (CANMAT) Taskforce.
Sarris J, Ravindran A, Yatham LN, Marx W, Rucklidge JJ, McIntyre RS, Akhondzadeh S, Benedetti F, Caneo C, Cramer H, Cribb L, de Manincor M, Dean O, Deslandes AC, Freeman MP, Gangadhar B, Harvey BH, Kasper S, Lake J, Lopresti A, Lu L, Metri NJ, Mischoulon D, Ng CH, Nishi D, Rahimi R, Seedat S, Sinclair J, Su KP, Zhang ZJ, Berk M. Sarris J, et al. World J Biol Psychiatry. 2022 Jul;23(6):424-455. doi: 10.1080/15622975.2021.2013041. Epub 2022 Mar 21. World J Biol Psychiatry. 2022. PMID: 35311615
Monotherapy omega-3 (+/-), folic acid (-), vitamin C (-), tryptophan (+/-), creatine (+/-), inositol (-), magnesium (-), and n-acetyl cysteine (NAC) (+/-) and SAMe (+/-) were not supported for this use. In bipolar disorder, omega-3 had weak support for bipolar depre …
Monotherapy omega-3 (+/-), folic acid (-), vitamin C (-), tryptophan (+/-), creatine (+/-), inositol (-), magnesium (-), and n-acetyl cystei …
Curcumin for neuropsychiatric disorders: a review of in vitro, animal and human studies.
Lopresti AL. Lopresti AL. J Psychopharmacol. 2017 Mar;31(3):287-302. doi: 10.1177/0269881116686883. Epub 2017 Jan 30. J Psychopharmacol. 2017. PMID: 28135888 Review.
In this systematic review, in vitro, animal, and human studies investigating the potential of curcumin as a treatment for neuropsychiatric disorders such as major depressive disorder, post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), bipolar …
In this systematic review, in vitro, animal, and human studies investigating the potential of curcumin as a treatment for neuropsychi …
Curcumin in depressive disorders: An overview of potential mechanisms, preclinical and clinical findings.
Kaufmann FN, Gazal M, Bastos CR, Kaster MP, Ghisleni G. Kaufmann FN, et al. Eur J Pharmacol. 2016 Aug 5;784:192-8. doi: 10.1016/j.ejphar.2016.05.026. Epub 2016 May 24. Eur J Pharmacol. 2016. PMID: 27235294 Review.
Most literature data focused on the potential of curcumin to counteract behavioral and neurochemical alterations in preclinical models of depression. ...Despite the limited number of reports, preclinical models investigated the potential role for curcumin in anxiety …
Most literature data focused on the potential of curcumin to counteract behavioral and neurochemical alterations in preclinical model …
The effect of adding curcumin to sodium valproate in treatment of patients with bipolar disorder in the acute phase of mania: A randomized double-blind clinical trial.
Akbarzadeh F, Niksun N, Behravan G, Behdani F, Mohammadpour AH, Jaafari M, Hosseini T, Rajai Z, Ebrahimi A, Eslamzadeh M. Akbarzadeh F, et al. Front Psychiatry. 2023 Feb 2;14:1068277. doi: 10.3389/fpsyt.2023.1068277. eCollection 2023. Front Psychiatry. 2023. PMID: 36816417 Free PMC article.
BACKGROUND: Inflammatory processes play a role in the etiopathogenesis of bipolar disorder type 1. Full therapeutic responses are seldom seen and the ongoing inflammatory processes in the brain could lead to neuronal loss. Curcumin, a relatively safe herbal compound …
BACKGROUND: Inflammatory processes play a role in the etiopathogenesis of bipolar disorder type 1. Full therapeutic responses are sel …
Curcumin Protects beta-Lactoglobulin Fibril Formation and Fibril-Induced Neurotoxicity in PC12 Cells.
Mazaheri M, Moosavi-Movahedi AA, Saboury AA, Khodagholi F, Shaerzadeh F, Sheibani N. Mazaheri M, et al. PLoS One. 2015 Jul 17;10(7):e0133206. doi: 10.1371/journal.pone.0133206. eCollection 2015. PLoS One. 2015. PMID: 26186474 Free PMC article.
However, the adverse effects of these toxins and protein fibrils were negated in the presence of curcumin. Furthermore, the antioxidant and inhibitory effects of curcumin protected PC12 cells against fibril neurotoxicity and enhanced their survival. Thus, curcumi …
However, the adverse effects of these toxins and protein fibrils were negated in the presence of curcumin. Furthermore, the antioxida …
Therapeutic approaches employing natural compounds and derivatives for treating bipolar disorder: emphasis on experimental models of the manic phase.
Recart VM, Spohr L, Soares MSP, Luduvico KP, Stefanello FM, Spanevello RM. Recart VM, et al. Metab Brain Dis. 2021 Oct;36(7):1481-1499. doi: 10.1007/s11011-021-00776-7. Epub 2021 Jul 15. Metab Brain Dis. 2021. PMID: 34264451 Review.
Bipolar disorder (BD) is a complex psychiatric disease characterized by mood swings that include episodes of mania and depression. ...In animal models, it has been shown that red fruits extracts, curcumin, quercetin, gallic acid, alpha-lipoic acid and carvone can mo …
Bipolar disorder (BD) is a complex psychiatric disease characterized by mood swings that include episodes of mania and depression. .. …
Ameliorative Effect of Curcumin on Olanzapine-induced Obesity in Sprague-Dawley Rats.
Parasuraman S, Zhen KM, Banik U, Christapher PV. Parasuraman S, et al. Pharmacognosy Res. 2017 Jul-Sep;9(3):247-252. doi: 10.4103/pr.pr_8_17. Pharmacognosy Res. 2017. PMID: 28827965 Free PMC article.
The effect of curcumin on olanzapine-induced body weight gain is not comparable with that of betahistine. CONCLUSION: This study has shown metabolic alteration effect of curcumin on olanzapine, an antipsychotic drug, treated SD rats. SUMMARY: Olanzapine is an atypic …
The effect of curcumin on olanzapine-induced body weight gain is not comparable with that of betahistine. CONCLUSION: This study has …
Nutraceuticals in mood disorders: current knowledge and future directions.
Travica N, Teasdale S, Marx W. Travica N, et al. Curr Opin Psychiatry. 2023 Jan 1;36(1):54-59. doi: 10.1097/YCO.0000000000000826. Epub 2022 Aug 29. Curr Opin Psychiatry. 2023. PMID: 36044293 Review.
RECENT FINDINGS: Nutraceuticals such as omega-3, probiotics, zinc, saffron and curcumin have been recommended as adjunctive interventions to standard treatments for people with depression, while St John's wort has been recommended as a monotherapy. In contrast, less resear …
RECENT FINDINGS: Nutraceuticals such as omega-3, probiotics, zinc, saffron and curcumin have been recommended as adjunctive intervent …
Putative neuroprotective pharmacotherapies to target the staged progression of mental illness.
Robertson OD, Coronado NG, Sethi R, Berk M, Dodd S. Robertson OD, et al. Early Interv Psychiatry. 2019 Oct;13(5):1032-1049. doi: 10.1111/eip.12775. Epub 2019 Jan 28. Early Interv Psychiatry. 2019. PMID: 30690898 Review.
AIM: Neuropsychiatric disorders including depression, bipolar and schizophrenia frequently exhibit a neuroprogressive course from prodrome to chronicity. ...Agents include: the psychotropic medications lithium, second generation antipsychotics and antidepressants; other ph …
AIM: Neuropsychiatric disorders including depression, bipolar and schizophrenia frequently exhibit a neuroprogressive course from pro …
15 results