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Page 1
A Review of the Role of an Anthocyanin, Cyanidin-3-O-β-glucoside in Obesity-Related Complications.
Deepa P, Hong M, Sowndhararajan K, Kim S. Deepa P, et al. Plants (Basel). 2023 Nov 17;12(22):3889. doi: 10.3390/plants12223889. Plants (Basel). 2023. PMID: 38005786 Free PMC article. Review.
C3G has various biological properties and health benefits, such as antioxidant, antimicrobial, anti-inflammatory, antidiabetic, anti-obesity, neuroprotective, anticancer, etc. In this review, we summarized the in vitro and in vivo studies in relation to the role of C3G in …
C3G has various biological properties and health benefits, such as antioxidant, antimicrobial, anti-inflammatory, antidiabetic, anti-obesity …
Cyanidin-3-glucoside confers neuroprotection in ischemic stroke by targeting NOX4-mediated oxidative stress: A network pharmacology and experimental validation study.
Li X, Gao Y, Ye Y, Wang J, Xiong X, Zhang J, Wei L, Gu L. Li X, et al. Biomed Pharmacother. 2026 Feb;195:119072. doi: 10.1016/j.biopha.2026.119072. Epub 2026 Jan 29. Biomed Pharmacother. 2026. PMID: 41616469 Free article.
BACKGROUND: To investigate the neuroprotective effect of the dietary anthocyanin cyanidin-3-glucoside (C-3-G) in cerebral ischemia-reperfusion injury and elucidate its underlying molecular mechanisms by a network pharmacology and transcriptomics method …
BACKGROUND: To investigate the neuroprotective effect of the dietary anthocyanin cyanidin-3-glucoside (C-3-G) in …
Cyanidin-3-O-Glucoside Protects PC12 Cells Against Neuronal Apoptosis Mediated by LPS-Stimulated BV2 Microglial Activation.
Kaewmool C, Udomruk S, Phitak T, Pothacharoen P, Kongtawelert P. Kaewmool C, et al. Neurotox Res. 2020 Jan;37(1):111-125. doi: 10.1007/s12640-019-00102-1. Epub 2019 Sep 4. Neurotox Res. 2020. PMID: 31485933
Furthermore, a co-culture system to determine the indirect neuroprotective effects of C3G was used. Results demonstrated that conditioned medium (CM) from LPS-stimulated BV2 cells can promote the apoptosis of differentiated pheochromocytoma (PC12) cells through the activat …
Furthermore, a co-culture system to determine the indirect neuroprotective effects of C3G was used. Results demonstrated that conditi …
Cyanidin-3-glucoside activates Nrf2-antioxidant response element and protects against glutamate-induced oxidative and endoplasmic reticulum stress in HT22 hippocampal neuronal cells.
Sukprasansap M, Chanvorachote P, Tencomnao T. Sukprasansap M, et al. BMC Complement Med Ther. 2020 Feb 11;20(1):46. doi: 10.1186/s12906-020-2819-7. BMC Complement Med Ther. 2020. Retraction in: BMC Complement Med Ther. 2024 Oct 7;24(1):360. doi: 10.1186/s12906-024-04672-2. PMID: 32046712 Free PMC article. Retracted.
BACKGROUND: Cyanidin-3-glucoside (C3G), a major anthocyanin present in berries, exhibits a strong antioxidant and has been shown to possess a neuroprotection. ...In the present study, we investigated the neuroprotective effect and underlying mec …
BACKGROUND: Cyanidin-3-glucoside (C3G), a major anthocyanin present in berries, exhibits a strong antioxidant and has b …
A review of recent advances on cyanidin-3-glucoside: the biotransformation, absorption, bioactivity and applications of nano-encapsulation.
Yang M, Abdullah, Ahmad N, Hussain M, Lu X, Xu J, Zhong H, Guan R. Yang M, et al. Food Funct. 2023 Jul 17;14(14):6320-6345. doi: 10.1039/d2fo03824b. Food Funct. 2023. PMID: 37403833 Review.
The C3G metabolites possess health benefits such as antioxidant, cardio-protective, anti-inflammatory, neuroprotective, anti-cancer, anti-diabetic, and anti-thrombotic activities. However, the efficacy and distribution of C3G in the human body are restricted due to its low …
The C3G metabolites possess health benefits such as antioxidant, cardio-protective, anti-inflammatory, neuroprotective, anti-cancer, …
Cyanidin-3-glucoside improves cognitive impairment in naturally aging mice by modulating the gut microbiota and activating the ERK/CREB/BDNF pathway.
Chen Y, Qi W, Peng W, Fang W, Song G, Hao Y, Wang Y. Chen Y, et al. Food Res Int. 2025 May;208:116086. doi: 10.1016/j.foodres.2025.116086. Epub 2025 Feb 25. Food Res Int. 2025. PMID: 40263878
Aging-related cognitive impairment has emerged as a major health-threatening factor among the elderly, and cyanidin-3-glucoside (C3G) is a prominent anthocyanin with biological activities, including antioxidant, anti-inflammatory, and alleviation of neurodege …
Aging-related cognitive impairment has emerged as a major health-threatening factor among the elderly, and cyanidin-3-gluco …
Blue honeysuckle (Lonicera caerulea L.)-anthocyanins and cyanidin-3-O-glucoside protect dopaminergic neurons against ferroptosis by activating the Nrf2-GPX7 axis.
Li XN, Fan LL, Zhu Q, Liu JH, Xie ZY, Cao JL, Tan JY, Lin L, Li XS, Wei XH. Li XN, et al. Free Radic Biol Med. 2025 Nov;239:242-256. doi: 10.1016/j.freeradbiomed.2025.07.038. Epub 2025 Jul 28. Free Radic Biol Med. 2025. PMID: 40738179
However, the therapeutic potential and neuroprotective mechanisms of blue honeysuckle-anthocyanins (BH-an), especially C3G, in mitigating PD are yet to be fully elucidated. ...This study highlights the potential of blue honeysuckle anthocyanins, especially C3G, as preventi …
However, the therapeutic potential and neuroprotective mechanisms of blue honeysuckle-anthocyanins (BH-an), especially C3G, in mitiga …
Cyanidin-3-O-glucoside inhibits Aβ40 fibrillogenesis, disintegrates preformed fibrils, and reduces amyloid cytotoxicity.
Liu F , Zhao F , Wang W , Sang J , Jia L , Li L , Lu F . Liu F , et al. Food Funct. 2020 Mar 1;11(3):2573-2587. doi: 10.1039/c9fo00316a. Epub 2020 Mar 10. Food Funct. 2020. PMID: 32154523
Cyanidin-3-O-glucoside (Cy-3G) is a commonly found anthocyanin that is mainly present in fruits, with established neuroprotective effects in situ. However, it remains unknown if Cy-3G can prevent Abeta fibrillogenesis and alleviate the corresponding cytotoxicity. ...
Cyanidin-3-O-glucoside (Cy-3G) is a commonly found anthocyanin that is mainly present in fruits, with established neuroprotective eff …
Multi-Malonylation Enhances the Neuroprotection of Cyanidin-3-O-Glucoside by Promoting Gut-Derived 5-Hydroxytryptophan Production via Limosilactobacillus reuteri through the Gut-Brain Axis.
Li J, Chen G, Zhang T, Xiong G, Du C, Peng Y, Zeng X, Chen C. Li J, et al. J Agric Food Chem. 2025 Oct 15;73(41):26172-26189. doi: 10.1021/acs.jafc.5c09840. Epub 2025 Sep 24. J Agric Food Chem. 2025. PMID: 40990386
This study synthesized and structurally characterized malonylated derivatives of cyanidin-3-O-glucoside (C3G), namely cyanidin-3-O-(6-O-malonyl-beta-d-glucoside) (C3GM) and cyanidin-3-O-(3,6-O-dimalonyl-beta-d-glucoside) (C3GdM), and evaluated their neuroprotective effects …
This study synthesized and structurally characterized malonylated derivatives of cyanidin-3-O-glucoside (C3G), namely cyanidin-3-O-(6-O-malo …
56 results