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2008 1
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Page 1
Topical Stabilized Cysteamine as a New Treatment for Hyperpigmentation Disorders: Melasma, Post-Inflammatory Hyperpigmentation, and Lentigines.
Desai S, Hartman C, Grimes P, Shah S. Desai S, et al. J Drugs Dermatol. 2021 Dec 1;20(12):1276-1279. doi: 10.36849/jdd.6367. J Drugs Dermatol. 2021. PMID: 34898155 Clinical Trial.
Multiple studies now document that cysteamine is a potent skin depigmenting agent. Historically, its rapid oxidation and very offensive odor made it difficult for topical use until recently when stabilization of cysteamine was achieved. ...Stabilized cysteamine …
Multiple studies now document that cysteamine is a potent skin depigmenting agent. Historically, its rapid oxidation and very offensi …
Evaluation of the efficacy of cysteamine cream compared to hydroquinone in the treatment of melasma: A randomised, double-blinded trial.
Nguyen J, Remyn L, Chung IY, Honigman A, Gourani-Tehrani S, Wutami I, Wong C, Paul E, Rodrigues M. Nguyen J, et al. Australas J Dermatol. 2021 Feb;62(1):e41-e46. doi: 10.1111/ajd.13432. Epub 2020 Sep 27. Australas J Dermatol. 2021. PMID: 32981068 Clinical Trial.
BACKGROUND/OBJECTIVE: Melasma is a commonly acquired disorder of hyperpigmentation that often poses a therapeutic challenge for dermatologists. Recently, cysteamine cream has shown promising results compared to placebo. This study aims to determine the efficacy of …
BACKGROUND/OBJECTIVE: Melasma is a commonly acquired disorder of hyperpigmentation that often poses a therapeutic challenge for dermatologis …
Comparison of the efficacy of cysteamine 5% cream and hydroquinone 4%/ascorbic acid 3% combination cream in the treatment of epidermal melasma.
Sepaskhah M, Karimi F, Bagheri Z, Kasraee B. Sepaskhah M, et al. J Cosmet Dermatol. 2022 Jul;21(7):2871-2878. doi: 10.1111/jocd.15048. Epub 2022 May 16. J Cosmet Dermatol. 2022. PMID: 35510765 Clinical Trial.
AIM: To evaluate the effect of cysteamine 5% cream in the treatment of melasma. METHODS: Sixty-five of 80 patients completed this single-blind, randomized, controlled trial. The patients received cysteamine 5% or hydroquinone 4%/ascorbic acid 3% (HC) cream …
AIM: To evaluate the effect of cysteamine 5% cream in the treatment of melasma. METHODS: Sixty-five of 80 patients completed t …
Significant therapeutic response to cysteamine cream in a melasma patient resistant to Kligman's formula.
Kasraee B, Mansouri P, Farshi S. Kasraee B, et al. J Cosmet Dermatol. 2019 Feb;18(1):293-295. doi: 10.1111/jocd.12837. Epub 2018 Dec 11. J Cosmet Dermatol. 2019. PMID: 30537063
The use of cysteamine cream was well tolerated and did not induce any side effects during the 3-year follow-up of the patient. ...Considering the high efficacy of cysteamine cream, it is possible that it could replace mutagenic and carcinogenic depigme …
The use of cysteamine cream was well tolerated and did not induce any side effects during the 3-year follow-up of the patient. …
Efficacy of cysteamine cream in the treatment of epidermal melasma, evaluating by Dermacatch as a new measurement method: a randomized double blind placebo controlled study.
Farshi S, Mansouri P, Kasraee B. Farshi S, et al. J Dermatolog Treat. 2018 Mar;29(2):182-189. doi: 10.1080/09546634.2017.1351608. Epub 2017 Jul 26. J Dermatolog Treat. 2018. PMID: 28678558 Clinical Trial.
METHODS: Participating patients (n = 40) received either placebo (n = 20) or cysteamine cream (n = 20) in a double-blind placebo controlled study. Cysteamine cream or placebo was applied on the lesions once a day at bedtime throughout the four-month st …
METHODS: Participating patients (n = 40) received either placebo (n = 20) or cysteamine cream (n = 20) in a double-blind place …
Evaluation of the efficacy of cysteamine 5% cream in the treatment of epidermal melasma: a randomized double-blind placebo-controlled trial.
Mansouri P, Farshi S, Hashemi Z, Kasraee B. Mansouri P, et al. Br J Dermatol. 2015 Jul;173(1):209-17. doi: 10.1111/bjd.13424. Epub 2015 May 29. Br J Dermatol. 2015. PMID: 25251767 Clinical Trial.
METHODS: In this double-blind randomized study, participating patients (n = 50) received either placebo (n = 25) or cysteamine cream (n = 25). Cysteamine cream or placebo were applied on the lesions once a day at bedtime over 4 months. ...CONCLUSIONS: …
METHODS: In this double-blind randomized study, participating patients (n = 50) received either placebo (n = 25) or cysteamine cre …
Assessing the Effectiveness of Stabilized Cysteamine 5% Cream Compared to Hydroquinone 4%/Ascorbic Acid 3% Combination Cream in Treating Acne-induced Post-inflammatory Hyperpigmentation: A Randomized, Controlled Study.
Ahmadi K, Miri A, Bizaval Z, Sepaskhah M, Ranjbar S, Bagheri Z, Kasraee B. Ahmadi K, et al. J Clin Aesthet Dermatol. 2024 Apr;17(4):37-41. J Clin Aesthet Dermatol. 2024. PMID: 38638185 Free PMC article.
We randomized the patients to apply either cysteamine 5% or hydroquinone 4%/ascorbic acid 3% (HC) cream. Postacne hyperpigmentation index (PAHPI) and melanin index were the assessment measures after four months of treatment. ...LIMITATIONS: Limitations of our study …
We randomized the patients to apply either cysteamine 5% or hydroquinone 4%/ascorbic acid 3% (HC) cream. Postacne hyperpigment …
Clinical evaluation of efficacy, safety and tolerability of cysteamine 5% cream in comparison with modified Kligman's formula in subjects with epidermal melasma: A randomized, double-blind clinical trial study.
Karrabi M, David J, Sahebkar M. Karrabi M, et al. Skin Res Technol. 2021 Jan;27(1):24-31. doi: 10.1111/srt.12901. Epub 2020 Jun 25. Skin Res Technol. 2021. PMID: 32585079 Clinical Trial.
Subjects received either cysteamine 5% cream or an MKF (4% hydroquinone, 0.05% retinoic acid and 0.1% betamethasone). ...CONCLUSION: Cysteamine 5% cream showed greater efficacy as compared to MKF. It is thus proposed that cysteamine 5% cream …
Subjects received either cysteamine 5% cream or an MKF (4% hydroquinone, 0.05% retinoic acid and 0.1% betamethasone). ...CONCL …
Clinical evaluation of efficacy and tolerability of cysteamine 5% cream in comparison with tranexamic acid mesotherapy in subjects with melasma: a single-blind, randomized clinical trial study.
Karrabi M, Mansournia MA, Sharestanaki E, Abdollahnejad Y, Sahebkar M. Karrabi M, et al. Arch Dermatol Res. 2021 Sep;313(7):539-547. doi: 10.1007/s00403-020-02133-7. Epub 2020 Sep 2. Arch Dermatol Res. 2021. PMID: 32879998 Clinical Trial.
This study was aimed at evaluating the efficacy of Tranexamic Acid (TA) mesotherapy versus cysteamine 5% cream in the treatment of melasma. This single-blind, randomized clinical trial was conducted among 54 subjects between 2018 and 2019. Cysteamine 5% cr …
This study was aimed at evaluating the efficacy of Tranexamic Acid (TA) mesotherapy versus cysteamine 5% cream in the treatmen …
A case report on the use of topical cysteamine 5% cream in the management of refractory postinflammatory hyperpigmentation (PIH) resistant to triple combination cream (hydroquinone, topical corticosteroids, and retinoids).
Mathe N, Balogun M, Yoo J. Mathe N, et al. J Cosmet Dermatol. 2021 Jan;20(1):204-206. doi: 10.1111/jocd.13755. Epub 2020 Oct 31. J Cosmet Dermatol. 2021. PMID: 32997864
Treatment with cysteamine 5% cream over 4 months resulted in significant improvement with a reduction in the melanin index. ...Cysteamine 5% cream is one of the latest cosmetic skin lightening products. ...
Treatment with cysteamine 5% cream over 4 months resulted in significant improvement with a reduction in the melanin index. .. …
19 results