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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1992 1
1993 1
1996 1
1998 2
1999 3
2000 4
2001 2
2002 4
2003 7
2004 3
2005 2
2006 5
2007 3
2008 3
2009 4
2010 5
2011 10
2012 9
2013 7
2014 7
2015 12
2016 13
2017 8
2018 13
2019 10
2020 8
2021 7
2022 8
2023 7
2024 12
2025 9
2026 3

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165 results

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Page 1
Muscle-to-tumor crosstalk: The effect of exercise-induced myokine on cancer progression.
Huang Q, Wu M, Wu X, Zhang Y, Xia Y. Huang Q, et al. Biochim Biophys Acta Rev Cancer. 2022 Sep;1877(5):188761. doi: 10.1016/j.bbcan.2022.188761. Epub 2022 Jul 16. Biochim Biophys Acta Rev Cancer. 2022. PMID: 35850277 Review.
The amount of myokines secreted varies depending on the intensity, type, and duration of exercise. Recent studies have shown that muscle-derived myokines are highly involved the effects of exercise on cancer. ...It is characterized by systemic inflammation an …
The amount of myokines secreted varies depending on the intensity, type, and duration of exercise. Recent studies have shown that …
Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Results of a pilot clinical trial.
Kumar P, Liu C, Hsu JW, Chacko S, Minard C, Jahoor F, Sekhar RV. Kumar P, et al. Clin Transl Med. 2021 Mar;11(3):e372. doi: 10.1002/ctm2.372. Clin Transl Med. 2021. PMID: 33783984 Free PMC article.
This pilot trial in OA was conducted to test the effect of GlyNAC supplementation and withdrawal on intracellular GSH concentrations, OxS, MFO, inflammation, endothelial function, genotoxicity, muscle and glucose metabolism, body composition, strength, and cognition …
This pilot trial in OA was conducted to test the effect of GlyNAC supplementation and withdrawal on intracellular GSH concentrations, OxS, M …
Myokines: metabolic regulation in obesity and type 2 diabetes.
Chen ZT, Weng ZX, Lin JD, Meng ZX. Chen ZT, et al. Life Metab. 2024 Mar 2;3(3):loae006. doi: 10.1093/lifemeta/loae006. eCollection 2024 Jun. Life Metab. 2024. PMID: 39872377 Free PMC article. Review.
Skeletal muscle plays a vital role in the regulation of systemic metabolism, partly through its secretion of endocrine factors which are collectively known as myokines. ...Related to these, we detail the role of exercise in myokine expression and secretion to …
Skeletal muscle plays a vital role in the regulation of systemic metabolism, partly through its secretion of endocrine factors …
Exercise training mode effects on myokine expression in healthy adults: A systematic review with meta-analysis.
Bettariga F, Taaffe DR, Galvão DA, Lopez P, Bishop C, Markarian AM, Natalucci V, Kim JS, Newton RU. Bettariga F, et al. J Sport Health Sci. 2024 Nov;13(6):764-779. doi: 10.1016/j.jshs.2024.04.005. Epub 2024 Apr 10. J Sport Health Sci. 2024. PMID: 38604409 Free PMC article.
To date, the effects of different exercise modes (namely, aerobic and resistance exercise) on myokine response remain to be elucidated. ...Eligible studies examining the effects of a single bout of exercise on interleukin15 (IL-15), irisin, secreted protei …
To date, the effects of different exercise modes (namely, aerobic and resistance exercise) on myokine response remain to be el …
A 2-hydroxybutyrate-mediated feedback loop regulates muscular fatigue.
Wadsworth BJ, Leiwe M, Minogue EA, Cunha PP, Engman V, Brombach C, Asvestis C, Sah-Teli SK, Marklund E, Koivunen P, Ruas JL, Rundqvist H, Lanner JT, Johnson RS. Wadsworth BJ, et al. Elife. 2024 Sep 3;12:RP92707. doi: 10.7554/eLife.92707. Elife. 2024. PMID: 39226092 Free PMC article.
These include succinate, lactate, fumarate, and 2-hydroxyglutarate. 2-Hydroxybutyrate (2HB) is a byproduct of endogenous cysteine synthesis, produced during periods of cellular stress. 2HB rises acutely after exercise; it also rises during infection and is al …
These include succinate, lactate, fumarate, and 2-hydroxyglutarate. 2-Hydroxybutyrate (2HB) is a byproduct of endogenous cysteine …
Secreted Protein Acidic and Rich in Cysteine as an Exercise-Induced Gene: Towards Novel Molecular Therapies for Immobilization-Related Muscle Atrophy in Elderly Patients.
Ghanemi A, Yoshioka M, St-Amand J. Ghanemi A, et al. Genes (Basel). 2022 Jun 4;13(6):1014. doi: 10.3390/genes13061014. Genes (Basel). 2022. PMID: 35741776 Free PMC article.
Within this context, secreted protein acidic and rich in cysteine (SPARC) has been characterized as an exercise-induced gene. Whereas the knock-out of this gene leads to a phenotype that mimics number of the ageing-induced and sarcopenia-related changes inclu …
Within this context, secreted protein acidic and rich in cysteine (SPARC) has been characterized as an exercise-induced …
Secreted protein acidic and rich in cysteine and bioenergetics: Extracellular matrix, adipocytes remodeling and skeletal muscle metabolism.
Ghanemi A, Melouane A, Yoshioka M, St-Amand J. Ghanemi A, et al. Int J Biochem Cell Biol. 2019 Dec;117:105627. doi: 10.1016/j.biocel.2019.105627. Epub 2019 Oct 4. Int J Biochem Cell Biol. 2019. PMID: 31589923 Review.
The extracellular matrix (ECM) remodeling plays important roles in both adipocytes shape/expansion remodeling and the skeletal muscle (SM) metabolism. Secreted protein acidic and rich in cysteine (SPARC) is expressed in divers tissues including adipose …
The extracellular matrix (ECM) remodeling plays important roles in both adipocytes shape/expansion remodeling and the skeletal muscle …
Exercise-induced muscle injury: a calpain hypothesis.
Belcastro AN, Shewchuk LD, Raj DA. Belcastro AN, et al. Mol Cell Biochem. 1998 Feb;179(1-2):135-45. doi: 10.1023/a:1006816123601. Mol Cell Biochem. 1998. PMID: 9543356 Review.
The resulting elevation in intracellular [Ca2+] activates the non-lysosomal cysteine protease, calpain. Because calpain cleaves a variety of protein substrates including cytoskeletal and myofibrillar proteins, calpain-mediated degradation is thought to contri …
The resulting elevation in intracellular [Ca2+] activates the non-lysosomal cysteine protease, calpain. Because calpain cleaves a var …
Increasing Muscle Mass in Elders through Diet and Exercise: A Literature Review of Recent RCTs.
Voulgaridou G, Papadopoulou SD, Spanoudaki M, Kondyli FS, Alexandropoulou I, Michailidou S, Zarogoulidis P, Matthaios D, Giannakidis D, Romanidou M, Papadopoulou SK. Voulgaridou G, et al. Foods. 2023 Mar 13;12(6):1218. doi: 10.3390/foods12061218. Foods. 2023. PMID: 36981144 Free PMC article. Review.
The combination of exercise and diet is known to be a potent anabolic stimulus through stimulation of muscle protein synthesis from amino acids. ...Essential amino acids, such as leucine, arginine, cysteine, and glutamine, are of particular impo …
The combination of exercise and diet is known to be a potent anabolic stimulus through stimulation of muscle protein …
Nonsyndromic Malignant Hyperthermia Susceptibility.
Riazi S, Biesecker LG, Rosenberg H, Dirksen RT. Riazi S, et al. 2003 Dec 19 [updated 2025 Aug 7]. In: Adam MP, Bick S, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2026. 2003 Dec 19 [updated 2025 Aug 7]. In: Adam MP, Bick S, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2026. PMID: 20301325 Free Books & Documents. Review.
CLINICAL CHARACTERISTICS: Malignant hyperthermia susceptibility (MHS) is a pharmacogenetic disorder of skeletal muscle calcium regulation associated with uncontrolled skeletal muscle hypermetabolism. ...DIAGNOSIS/TESTING: The diagnosis of MHS is established with in …
CLINICAL CHARACTERISTICS: Malignant hyperthermia susceptibility (MHS) is a pharmacogenetic disorder of skeletal muscle calcium regula …
165 results