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Year Number of Results
1991 1
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1998 3
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2001 2
2002 7
2003 3
2004 2
2005 7
2006 4
2007 6
2008 8
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2010 10
2011 10
2012 4
2013 10
2014 10
2015 9
2016 7
2017 4
2018 8
2019 10
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2025 5
2026 3

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180 results

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Page 1
Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial.
Kumar P, Liu C, Suliburk J, Hsu JW, Muthupillai R, Jahoor F, Minard CG, Taffet GE, Sekhar RV. Kumar P, et al. J Gerontol A Biol Sci Med Sci. 2023 Jan 26;78(1):75-89. doi: 10.1093/gerona/glac135. J Gerontol A Biol Sci Med Sci. 2023. PMID: 35975308 Free PMC article. Clinical Trial.
Participants were studied before, after 2-weeks, and after 16-weeks of supplementation to assess GSH concentrations, OxS, MFO, molecular regulators of energy metabolism, inflammation, endothelial function, IR, aging hallmarks, gait speed, muscle strength, 6-minute walk tes …
Participants were studied before, after 2-weeks, and after 16-weeks of supplementation to assess GSH concentrations, OxS, MFO, molecu …
Antihypertensive Effects of an Optimized Aged Garlic Extract in Subjects with Grade I Hypertension and Antihypertensive Drug Therapy: A Randomized, Triple-Blind Controlled Trial.
Serrano JCE, Castro-Boqué E, García-Carrasco A, Morán-Valero MI, González-Hedström D, Bermúdez-López M, Valdivielso JM, Espinel AE, Portero-Otín M. Serrano JCE, et al. Nutrients. 2023 Aug 23;15(17):3691. doi: 10.3390/nu15173691. Nutrients. 2023. PMID: 37686723 Free PMC article. Clinical Trial.
This study aims to validate the antihypertensive effects of an optimized extract of aged black garlic with low doses of s-allyl-cysteine (SAC) in a Grade I hypertensive population with drug treatment. A randomized, triple-blind, placebo-controlled parallel trial was develo …
This study aims to validate the antihypertensive effects of an optimized extract of aged black garlic with low doses of s-allyl-cysteine …
The effects of the oral supplementation of L-Cystine associated with reduced L-Glutathione-GSH on human skin pigmentation: a randomized, double-blinded, benchmark- and placebo-controlled clinical trial.
Duperray J, Sergheraert R, Chalothorn K, Tachalerdmanee P, Perin F. Duperray J, et al. J Cosmet Dermatol. 2022 Feb;21(2):802-813. doi: 10.1111/jocd.14137. Epub 2021 Apr 22. J Cosmet Dermatol. 2022. PMID: 33834608 Clinical Trial.
AIMS: To evaluate the skin lightening and anti-dark spot effects of oral supplementation with L-Cystine associated with L-Glutathione as compared to placebo and benchmark. ...RESULTS: A significant skin lightening was observed after 12 weeks of oral supplementation …
AIMS: To evaluate the skin lightening and anti-dark spot effects of oral supplementation with L-Cystine associated with L-Glutathione …
Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (androgenetic alopecia, AGA or FAGA or telogen effluvium). A prospective, randomized, 3-month, controlled, assessor-blinded study.
Milani M, Colombo F; GFM‐O‐Trial Investigators Group. Milani M, et al. Skin Res Technol. 2023 Jun;29(6):e13381. doi: 10.1111/srt.13381. Skin Res Technol. 2023. PMID: 37357646 Free PMC article. Clinical Trial.
BACKGROUND: Oral supplementation with some amino acids (like methionine, taurine, and cysteine) could be useful in subjects with hair loss conditions such as androgenic alopecia (AGA or FAGA) or telogen effluvium (TE). Hydrolysed collagen (HC) oral supplementatio …
BACKGROUND: Oral supplementation with some amino acids (like methionine, taurine, and cysteine) could be useful in subjects wi …
Effectiveness of N-acetylcysteine in autism spectrum disorders: A meta-analysis of randomized controlled trials.
Lee TM, Lee KM, Lee CY, Lee HC, Tam KW, Loh EW. Lee TM, et al. Aust N Z J Psychiatry. 2021 Feb;55(2):196-206. doi: 10.1177/0004867420952540. Epub 2020 Sep 8. Aust N Z J Psychiatry. 2021. PMID: 32900213
DATA SYNTHESIS: After 8-12 weeks of N-acetylcysteine supplementation, the pooled result of four trials revealed an improvement in Aberrant Behavior Checklist total score (mean difference = 1.31, 95% confidence interval = [0.42, 2.20]). ...Regarding Social Responsiveness Sc …
DATA SYNTHESIS: After 8-12 weeks of N-acetylcysteine supplementation, the pooled result of four trials revealed an improvement in Abe …
N-acetylcysteine supplementation improves endocrine-metabolism profiles and ovulation induction efficacy in polycystic ovary syndrome.
Fang YQ, Ding H, Li T, Zhao XJ, Luo D, Liu Y, Li Y. Fang YQ, et al. J Ovarian Res. 2024 Oct 16;17(1):205. doi: 10.1186/s13048-024-01528-8. J Ovarian Res. 2024. PMID: 39415242 Free PMC article. Clinical Trial.
Our current study aimed to investigate the effects of NAC supplementation on endocrine-metabolic parameters in PCOS mice and its effect on ovulation induction (OI) efficacy in women with PCOS. ...RESULTS: Similar to metformin, NAC supplementation significantly impro …
Our current study aimed to investigate the effects of NAC supplementation on endocrine-metabolic parameters in PCOS mice and its effe …
Effects of Selenium and/or N-Acetyl-Cysteine Supplementation on Nonthyroidal Illness Syndrome in Hemodialysis Patients: A Factorial Randomized Controlled Trial.
Shahreki E, Kaykhaei MA, Mosallanezhad Z, Adineh Z, Mokhtari AM, Mohammadi M, Hosseini R, Bazi A. Shahreki E, et al. Pharmacology. 2022;107(9-10):480-485. doi: 10.1159/000525094. Epub 2022 Jun 10. Pharmacology. 2022. PMID: 35691282 Clinical Trial.
Therefore, the aim of this study was to investigate the effect of Se and/or N-acetyl-cysteine (NAC) on NTIS parameters in HPs. METHODS: In this factorial randomized controlled trial, 68 HPs were divided into four groups: group A received placebo of Se …
Therefore, the aim of this study was to investigate the effect of Se and/or N-acetyl-cysteine (NAC) on NTIS parameters in HPs. METHOD …
Changes to insulin sensitivity in glucose clearance systems and redox following dietary supplementation with a novel cysteine-rich protein: A pilot randomized controlled trial in humans with type-2 diabetes.
Peeters WM, Gram M, Dias GJ, Vissers MCM, Hampton MB, Dickerhof N, Bekhit AE, Black MJ, Oxbøll J, Bayer S, Dickens M, Vitzel K, Sheard PW, Danielson KM, Hodges LD, Brønd JC, Bond J, Perry BG, Stoner L, Cornwall J, Rowlands DS. Peeters WM, et al. Redox Biol. 2023 Nov;67:102918. doi: 10.1016/j.redox.2023.102918. Epub 2023 Oct 5. Redox Biol. 2023. PMID: 37812879 Free PMC article. Clinical Trial.
We recently developed a novel keratin-derived protein (KDP) rich in cysteine, glycine, and arginine, with the potential to alter tissue redox status and insulin sensitivity. The KDP was tested in 35 human adults with type-2 diabetes mellitus (T2DM) in a 14-wk randomised co …
We recently developed a novel keratin-derived protein (KDP) rich in cysteine, glycine, and arginine, with the potential to alter tiss …
Sensitization of GSH synthesis by curcumin curtails acrolein-induced alveolar epithelial apoptosis via Keap1 cysteine conjugation: A randomized controlled trial and experimental animal model of pneumonitis.
Hee Jo E, Eun Moon J, Han Chang M, Jin Lim Y, Hyun Park J, Hee Lee S, Rae Cho Y, Cho AE, Pil Pack S, Kim HW, Crowley L, Le B, Nukhet AB, Chen Y, Zhong Y, Zhao J, Li Y, Cha H, Hoon Pan J, Kyeom Kim J, Hyup Lee J. Hee Jo E, et al. J Adv Res. 2023 Apr;46:17-29. doi: 10.1016/j.jare.2022.06.013. Epub 2022 Jun 27. J Adv Res. 2023. PMID: 35772713 Free PMC article.
Twelve hours after single acrolein exposure, all mice were euthanized. RESULTS: Curcumin supplementation, with no noticeable adverse responses, reduced circulating pro-inflammatory cytokines in association with clinical pneumonitis as positive predictive while improving th …
Twelve hours after single acrolein exposure, all mice were euthanized. RESULTS: Curcumin supplementation, with no noticeable adverse …
Unlocking the potential of antioxidant supplementation with n-acetylcysteine to improve seminal parameters and analysis of its safety: a systematic review and meta-analysis of randomized controlled trials.
Syarif S, Makkaraka MAG, Zainal ATF, Birowo P, Atmoko W. Syarif S, et al. Arch Ital Urol Androl. 2025 Mar 28;97(1):13750. doi: 10.4081/aiua.2025.13750. Epub 2025 Mar 24. Arch Ital Urol Androl. 2025. PMID: 40126496 Free article.
INTRODUCTION AND OBJECTIVES: N-acetyl-cysteine (NAC) is one of the oldest and most powerful antioxidants used to treat various diseases. ...These findings highlight the potential role of NAC as a safe supplementation for male with infertility or in male with impaire …
INTRODUCTION AND OBJECTIVES: N-acetyl-cysteine (NAC) is one of the oldest and most powerful antioxidants used to treat various diseas …
180 results