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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1974 1
1975 1
1976 1
1979 1
1980 1
1981 3
1982 1
1983 2
1984 1
1988 1
1989 1
1990 3
1991 1
1992 2
1993 5
1994 2
1995 6
1996 6
1997 3
1998 8
1999 10
2000 9
2001 16
2002 18
2003 18
2004 23
2005 14
2006 26
2007 15
2008 19
2009 24
2010 22
2011 14
2012 10
2013 19
2014 16
2015 13
2016 13
2017 17
2018 16
2019 12
2020 16
2021 17
2022 4
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388 results
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Page 1
Glutathione metabolism and its implications for health.
Wu G, Fang YZ, Yang S, Lupton JR, Turner ND. Wu G, et al. J Nutr. 2004 Mar;134(3):489-92. doi: 10.1093/jn/134.3.489. J Nutr. 2004. PMID: 14988435 Review.
Glutathione (gamma-glutamyl-cysteinyl-glycine; GSH) is the most abundant low-molecular-weight thiol, and GSH/glutathione disulfide is the major redox couple in animal cells. ...Glutathione deficiency contributes to oxidative stress, which plays a key role in
Glutathione (gamma-glutamyl-cysteinyl-glycine; GSH) is the most abundant low-molecular-weight thiol, and GSH/glutathione disul
Oral Glutathione and Growth in Cystic Fibrosis: A Multicenter, Randomized, Placebo-controlled, Double-blind Trial.
Bozic M, Goss CH, Tirouvanziam RM, Baines A, Kloster M, Antoine L, Borowitz D, Schwarzenberg SJ; GROW study group. Bozic M, et al. J Pediatr Gastroenterol Nutr. 2020 Dec;71(6):771-777. doi: 10.1097/MPG.0000000000002948. J Pediatr Gastroenterol Nutr. 2020. PMID: 32960827 Free PMC article. Clinical Trial.
OBJECTIVES: The nutritional status of children with cystic fibrosis (CF) is associated with mortality and morbidity. Intestinal inflammation may contribute to impaired digestion, absorption, and nutrient utilization in patients with CF and oral glutathione ma …
OBJECTIVES: The nutritional status of children with cystic fibrosis (CF) is associated with mortality and morbidity. Intestina …
Pseudomonas aeruginosa in cystic fibrosis: pathogenesis and persistence.
Davies JC. Davies JC. Paediatr Respir Rev. 2002 Jun;3(2):128-34. doi: 10.1016/s1526-0550(02)00003-3. Paediatr Respir Rev. 2002. PMID: 12297059 Review.
Pseudomonas aeruginosa is the major pathogen in the cystic fibrosis (CF) lung. Prevalence is high and, once acquired, chronic infection will almost always ensue. ...These include abnormalities of airway surface liquid leading to impaired mucociliary clearance or mal …
Pseudomonas aeruginosa is the major pathogen in the cystic fibrosis (CF) lung. Prevalence is high and, once acquired, chronic …
Novel Therapy of Bicarbonate, Glutathione, and Ascorbic Acid Improves Cystic Fibrosis Mucus Transport.
Adewale AT, Falk Libby E, Fu L, Lenzie A, Boitet ER, Birket SE, Petty CF, Johns JD, Mazur M, Tearney GJ, Copeland D, Durham C, Rowe SM. Adewale AT, et al. Am J Respir Cell Mol Biol. 2020 Sep;63(3):362-373. doi: 10.1165/rcmb.2019-0287OC. Am J Respir Cell Mol Biol. 2020. PMID: 32374624 Free PMC article.
Defective airway mucus clearance is a defining characteristic of cystic fibrosis lung disease, and improvements to current mucolytic strategies are needed. ...This response was absent in CFBE41o(-) F508del cells treated with VX-809 and primary human bronchial epithe …
Defective airway mucus clearance is a defining characteristic of cystic fibrosis lung disease, and improvements to current muc …
New insights into the pathogenesis of cystic fibrosis: pivotal role of glutathione system dysfunction and implications for therapy.
Hudson VM. Hudson VM. Treat Respir Med. 2004;3(6):353-63. doi: 10.2165/00151829-200403060-00003. Treat Respir Med. 2004. PMID: 15658882 Review.
The cystic fibrosis transmembrane regulator (CFTR) should no longer be viewed primarily as a 'chloride channel' but recognized as a channel that also controls the efflux of other physiologically important anions, such as glutathione (GSH) and bicarbonate. ... …
The cystic fibrosis transmembrane regulator (CFTR) should no longer be viewed primarily as a 'chloride channel' but recognized …
N-Acetylcysteine: A Review of Clinical Usefulness (an Old Drug with New Tricks).
Schwalfenberg GK. Schwalfenberg GK. J Nutr Metab. 2021 Jun 9;2021:9949453. doi: 10.1155/2021/9949453. eCollection 2021. J Nutr Metab. 2021. PMID: 34221501 Free PMC article. Review.
OBJECTIVE: To review the clinical usefulness of N-acetylcysteine (NAC) as treatment or adjunctive therapy in a number of medical conditions. Use in Tylenol overdose, cystic fibrosis, and chronic obstructive lung disease has been well documented, but there is emergin …
OBJECTIVE: To review the clinical usefulness of N-acetylcysteine (NAC) as treatment or adjunctive therapy in a number of medical conditions. …
Cystic fibrosis-related oxidative stress and intestinal lipid disorders.
Kleme ML, Levy E. Kleme ML, et al. Antioxid Redox Signal. 2015 Mar 1;22(7):614-31. doi: 10.1089/ars.2014.6012. Epub 2015 Jan 22. Antioxid Redox Signal. 2015. PMID: 25611180 Free PMC article. Review.
SIGNIFICANCE: Cystic fibrosis (CF) is the most common lethal genetic disorder in the Caucasian people. It is due to the mutation of cystic fibrosis transmembrane conductance regulator (CFTR) gene located on the long arm of the chromosome 7, which encod …
SIGNIFICANCE: Cystic fibrosis (CF) is the most common lethal genetic disorder in the Caucasian people. It is due to the mutati …
Rethinking cystic fibrosis pathology: the critical role of abnormal reduced glutathione (GSH) transport caused by CFTR mutation.
Hudson VM. Hudson VM. Free Radic Biol Med. 2001 Jun 15;30(12):1440-61. doi: 10.1016/s0891-5849(01)00530-5. Free Radic Biol Med. 2001. PMID: 11390189 Review.
Though the cause of cystic fibrosis (CF) pathology is understood to be the mutation of the CFTR protein, it has been difficult to trace the exact mechanisms by which the pathology arises and progresses from the mutation. Recent research findings have noted that the …
Though the cause of cystic fibrosis (CF) pathology is understood to be the mutation of the CFTR protein, it has been difficult …
Novel Antioxidant Therapy with the Immediate Precursor to Glutathione, γ-Glutamylcysteine (GGC), Ameliorates LPS-Induced Cellular Stress in In Vitro 3D-Differentiated Airway Model from Primary Cystic Fibrosis Human Bronchial Cells.
Hewson CK, Capraro A, Wong SL, Pandzic E, Zhong L, Fernando BSM, Awatade NT, Hart-Smith G, Whan RM, Thomas SR, Jaffe A, Bridge WJ, Waters SA. Hewson CK, et al. Antioxidants (Basel). 2020 Nov 30;9(12):1204. doi: 10.3390/antiox9121204. Antioxidants (Basel). 2020. PMID: 33266084 Free PMC article.
Systemic glutathione deficiency, inflammation, and oxidative stress are hallmarks of cystic fibrosis (CF), an inherited disease that causes persistent lung infections and severe damage to the respiratory system and many of the body organs. ...Together, these …
Systemic glutathione deficiency, inflammation, and oxidative stress are hallmarks of cystic fibrosis (CF), an inherited …
388 results