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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1974 1
1975 1
1976 1
1979 1
1980 1
1981 3
1982 1
1983 2
1984 1
1988 1
1989 1
1990 3
1991 1
1992 2
1993 5
1994 2
1995 6
1996 6
1997 3
1998 8
1999 10
2000 9
2001 16
2002 18
2003 18
2004 23
2005 14
2006 26
2007 15
2008 19
2009 24
2010 22
2011 14
2012 10
2013 19
2014 16
2015 13
2016 13
2017 17
2018 16
2019 12
2020 16
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368 results
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Page 1
Efficacy of Glutathione for Patients With Cystic Fibrosis: A Meta-analysis of Randomized-Controlled Studies.
Zhao J, Huang W, Zhang S, Xu J, Xue W, He B, Zhang Y. Zhao J, et al. Am J Rhinol Allergy. 2020 Jan;34(1):115-121. doi: 10.1177/1945892419878315. Epub 2019 Sep 24. Am J Rhinol Allergy. 2020. PMID: 31550169 Review. No abstract available.
Improved glutathione status in young adult patients with cystic fibrosis supplemented with whey protein.
Grey V, Mohammed SR, Smountas AA, Bahlool R, Lands LC. Grey V, et al. J Cyst Fibros. 2003 Dec;2(4):195-8. doi: 10.1016/S1569-1993(03)00097-3. J Cyst Fibros. 2003. PMID: 15463873 Free article. Clinical Trial.
This increased demand for glutathione (GSH) in cystic fibrosis may be limiting if nutritional status is compromised. We sought to increase glutathione levels in stable patients with cystic fibrosis by supplementation with a whey-based pro …
This increased demand for glutathione (GSH) in cystic fibrosis may be limiting if nutritional status is compromised. We …
Glutathione metabolism and its implications for health.
Wu G, Fang YZ, Yang S, Lupton JR, Turner ND. Wu G, et al. J Nutr. 2004 Mar;134(3):489-92. doi: 10.1093/jn/134.3.489. J Nutr. 2004. PMID: 14988435 Review.
Glutathione (gamma-glutamyl-cysteinyl-glycine; GSH) is the most abundant low-molecular-weight thiol, and GSH/glutathione disulfide is the major redox couple in animal cells. ...Glutathione deficiency contributes to oxidative stress, which plays a key role in
Glutathione (gamma-glutamyl-cysteinyl-glycine; GSH) is the most abundant low-molecular-weight thiol, and GSH/glutathione disul
Oxidative stress in early cystic fibrosis lung disease is exacerbated by airway glutathione deficiency.
Dickerhof N, Pearson JF, Hoskin TS, Berry LJ, Turner R, Sly PD, Kettle AJ; AREST CF. Dickerhof N, et al. Free Radic Biol Med. 2017 Dec;113:236-243. doi: 10.1016/j.freeradbiomed.2017.09.028. Epub 2017 Oct 2. Free Radic Biol Med. 2017. PMID: 28982600
Neutrophil-derived myeloperoxidase (MPO) is recognized as a major source of oxidative stress at the airway surface of a cystic fibrosis (CF) lung where, despite limited evidence, the antioxidant glutathione is widely considered to be low. ...MPO was measured …
Neutrophil-derived myeloperoxidase (MPO) is recognized as a major source of oxidative stress at the airway surface of a cystic fib
New insights into the pathogenesis of cystic fibrosis: pivotal role of glutathione system dysfunction and implications for therapy.
Hudson VM. Hudson VM. Treat Respir Med. 2004;3(6):353-63. doi: 10.2165/00151829-200403060-00003. Treat Respir Med. 2004. PMID: 15658882 Review.
The cystic fibrosis transmembrane regulator (CFTR) should no longer be viewed primarily as a 'chloride channel' but recognized as a channel that also controls the efflux of other physiologically important anions, such as glutathione (GSH) and bicarbonate. ... …
The cystic fibrosis transmembrane regulator (CFTR) should no longer be viewed primarily as a 'chloride channel' but recognized …
Oxidation contributes to low glutathione in the airways of children with cystic fibrosis.
Kettle AJ, Turner R, Gangell CL, Harwood DT, Khalilova IS, Chapman AL, Winterbourn CC, Sly PD; AREST CF. Kettle AJ, et al. Eur Respir J. 2014 Jul;44(1):122-9. doi: 10.1183/09031936.00170213. Epub 2014 Mar 23. Eur Respir J. 2014. PMID: 24659542 Free article.
The percentage of glutathione attached to proteins was higher in children with cystic fibrosis than controls. ...The concentration of glutathione is low in the airways of patients with cystic fibrosis from an early age. ...
The percentage of glutathione attached to proteins was higher in children with cystic fibrosis than controls. ...The co …
Antioxidant supplementation for lung disease in cystic fibrosis.
Ciofu O, Smith S, Lykkesfeldt J. Ciofu O, et al. Cochrane Database Syst Rev. 2019 Oct 3;10(10):CD007020. doi: 10.1002/14651858.CD007020.pub4. Online ahead of print. Cochrane Database Syst Rev. 2019. PMID: 31580490 Free PMC article. Review.
BACKGROUND: Airway infection leads to progressive damage of the lungs in cystic fibrosis (CF) and oxidative stress has been implicated in the etiology. ...SEARCH METHODS: The Cochrane Cystic Fibrosis and Genetic Disorders Group's Cystic Fibro
BACKGROUND: Airway infection leads to progressive damage of the lungs in cystic fibrosis (CF) and oxidative stress has been im …
Cystic fibrosis-related oxidative stress and intestinal lipid disorders.
Kleme ML, Levy E. Kleme ML, et al. Antioxid Redox Signal. 2015 Mar 1;22(7):614-31. doi: 10.1089/ars.2014.6012. Epub 2015 Jan 22. Antioxid Redox Signal. 2015. PMID: 25611180 Free PMC article. Review.
SIGNIFICANCE: Cystic fibrosis (CF) is the most common lethal genetic disorder in the Caucasian people. It is due to the mutation of cystic fibrosis transmembrane conductance regulator (CFTR) gene located on the long arm of the chromosome 7, which encod …
SIGNIFICANCE: Cystic fibrosis (CF) is the most common lethal genetic disorder in the Caucasian people. It is due to the mutati …
Novel Therapy of Bicarbonate, Glutathione, and Ascorbic Acid Improves Cystic Fibrosis Mucus Transport.
Adewale AT, Falk Libby E, Fu L, Lenzie A, Boitet ER, Birket SE, Petty CF, Johns JD, Mazur M, Tearney GJ, Copeland D, Durham C, Rowe SM. Adewale AT, et al. Am J Respir Cell Mol Biol. 2020 Sep;63(3):362-373. doi: 10.1165/rcmb.2019-0287OC. Am J Respir Cell Mol Biol. 2020. PMID: 32374624
Defective airway mucus clearance is a defining characteristic of cystic fibrosis lung disease, and improvements to current mucolytic strategies are needed. ...This response was absent in CFBE41o(-) F508del cells treated with VX-809 and primary human bronchial epithe …
Defective airway mucus clearance is a defining characteristic of cystic fibrosis lung disease, and improvements to current muc …
Rethinking cystic fibrosis pathology: the critical role of abnormal reduced glutathione (GSH) transport caused by CFTR mutation.
Hudson VM. Hudson VM. Free Radic Biol Med. 2001 Jun 15;30(12):1440-61. doi: 10.1016/s0891-5849(01)00530-5. Free Radic Biol Med. 2001. PMID: 11390189 Review.
Though the cause of cystic fibrosis (CF) pathology is understood to be the mutation of the CFTR protein, it has been difficult to trace the exact mechanisms by which the pathology arises and progresses from the mutation. Recent research findings have noted that the …
Though the cause of cystic fibrosis (CF) pathology is understood to be the mutation of the CFTR protein, it has been difficult …
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