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Cellular senescence: when bad things happen to good cells.
Campisi J, d'Adda di Fagagna F. Campisi J, et al. Nat Rev Mol Cell Biol. 2007 Sep;8(9):729-40. doi: 10.1038/nrm2233. Nat Rev Mol Cell Biol. 2007. PMID: 17667954 Review.
A DNA damage checkpoint response in telomere-initiated senescence.
d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, Saretzki G, Carter NP, Jackson SP. d'Adda di Fagagna F, et al. Nature. 2003 Nov 13;426(6963):194-8. doi: 10.1038/nature02118. Epub 2003 Nov 5. Nature. 2003. PMID: 14608368
Human cell senescence as a DNA damage response.
von Zglinicki T, Saretzki G, Ladhoff J, d'Adda di Fagagna F, Jackson SP. von Zglinicki T, et al. Mech Ageing Dev. 2005 Jan;126(1):111-7. doi: 10.1016/j.mad.2004.09.034. Mech Ageing Dev. 2005. PMID: 15610769 Review.
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication.
Di Micco R, Fumagalli M, Cicalese A, Piccinin S, Gasparini P, Luise C, Schurra C, Garre' M, Nuciforo PG, Bensimon A, Maestro R, Pelicci PG, d'Adda di Fagagna F. Di Micco R, et al. Nature. 2006 Nov 30;444(7119):638-42. doi: 10.1038/nature05327. Nature. 2006. PMID: 17136094
Breaking news: high-speed race ends in arrest--how oncogenes induce senescence.
Di Micco R, Fumagalli M, d'Adda di Fagagna F. Di Micco R, et al. Trends Cell Biol. 2007 Nov;17(11):529-36. doi: 10.1016/j.tcb.2007.07.012. Epub 2007 Nov 5. Trends Cell Biol. 2007. PMID: 17980599 Review.
Cellular senescence and cellular longevity: nearly 50 years on and still working on it.
d'Adda di Fagagna F. d'Adda di Fagagna F. Exp Cell Res. 2008 Jun 10;314(9):1907-8. doi: 10.1016/j.yexcr.2008.04.001. Epub 2008 Apr 8. Exp Cell Res. 2008. PMID: 18474280 No abstract available.
Chemokine signaling via the CXCR2 receptor reinforces senescence.
Acosta JC, O'Loghlen A, Banito A, Guijarro MV, Augert A, Raguz S, Fumagalli M, Da Costa M, Brown C, Popov N, Takatsu Y, Melamed J, d'Adda di Fagagna F, Bernard D, Hernando E, Gil J. Acosta JC, et al. Cell. 2008 Jun 13;133(6):1006-18. doi: 10.1016/j.cell.2008.03.038. Cell. 2008. PMID: 18555777
Living on a break: cellular senescence as a DNA-damage response.
d'Adda di Fagagna F. d'Adda di Fagagna F. Nat Rev Cancer. 2008 Jul;8(7):512-22. doi: 10.1038/nrc2440. Nat Rev Cancer. 2008. PMID: 18574463 Review.
Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells.
Santoriello C, Deflorian G, Pezzimenti F, Kawakami K, Lanfrancone L, d'Adda di Fagagna F, Mione M. Santoriello C, et al. Dis Model Mech. 2009 Jan-Feb;2(1-2):56-67. doi: 10.1242/dmm.001016. Epub 2008 Dec 22. Dis Model Mech. 2009. PMID: 19132118 Free PMC article.
Cellular senescence: hot or what?
Evan GI, d'Adda di Fagagna F. Evan GI, et al. Curr Opin Genet Dev. 2009 Feb;19(1):25-31. doi: 10.1016/j.gde.2008.11.009. Epub 2009 Jan 30. Curr Opin Genet Dev. 2009. PMID: 19181515 Review.
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