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In vitro and in vivo studies of the antiparasitic activity of sterol 14α-demethylase (CYP51) inhibitor VNI against drug-resistant strains of Trypanosoma cruzi.
Soeiro Mde N, de Souza EM, da Silva CF, Batista Dda G, Batista MM, Pavão BP, Araújo JS, Aiub CA, da Silva PB, Lionel J, Britto C, Kim K, Sulikowski G, Hargrove TY, Waterman MR, Lepesheva GI. Soeiro Mde N, et al. Among authors: da silva cf, da silva pb. Antimicrob Agents Chemother. 2013 Sep;57(9):4151-63. doi: 10.1128/AAC.00070-13. Epub 2013 Jun 17. Antimicrob Agents Chemother. 2013. PMID: 23774435 Free PMC article.
In vitro and in vivo studies of the trypanocidal activity of a diarylthiophene diamidine against Trypanosoma cruzi.
da Silva CF, Batista MM, Batista Dda G, de Souza EM, da Silva PB, de Oliveira GM, Meuser AS, Shareef AR, Boykin DW, Soeiro Mde N. da Silva CF, et al. Among authors: da silva pb. Antimicrob Agents Chemother. 2008 Sep;52(9):3307-14. doi: 10.1128/AAC.00038-08. Epub 2008 Jul 14. Antimicrob Agents Chemother. 2008. PMID: 18625779 Free PMC article.
Trypanosoma cruzi: activity of heterocyclic cationic molecules in vitro.
Pacheco MG, da Silva CF, de Souza EM, Batista MM, da Silva PB, Kumar A, Stephens CE, Boykin DW, Soeiro Mde N. Pacheco MG, et al. Among authors: da silva cf, da silva pb. Exp Parasitol. 2009 Sep;123(1):73-80. doi: 10.1016/j.exppara.2009.06.004. Epub 2009 Jun 9. Exp Parasitol. 2009. PMID: 19520077
In vitro and in vivo investigation of the efficacy of arylimidamide DB1831 and its mesylated salt form--DB1965--against Trypanosoma cruzi infection.
da Silva CF, Batista Dda G, Oliveira GM, de Souza EM, Hammer ER, da Silva PB, Daliry A, Araujo JS, Britto C, Rodrigues AC, Liu Z, Farahat AA, Kumar A, Boykin DW, Soeiro Mde N. da Silva CF, et al. Among authors: da silva pb. PLoS One. 2012;7(1):e30356. doi: 10.1371/journal.pone.0030356. Epub 2012 Jan 23. PLoS One. 2012. PMID: 22291940 Free PMC article.
Activities of psilostachyin A and cynaropicrin against Trypanosoma cruzi in vitro and in vivo.
da Silva CF, Batista Dda G, De Araújo JS, Batista MM, Lionel J, de Souza EM, Hammer ER, da Silva PB, De Mieri M, Adams M, Zimmermann S, Hamburger M, Brun R, Schühly W, Soeiro Mde N. da Silva CF, et al. Among authors: da silva pb. Antimicrob Agents Chemother. 2013 Nov;57(11):5307-14. doi: 10.1128/AAC.00595-13. Epub 2013 Aug 12. Antimicrob Agents Chemother. 2013. PMID: 23939901 Free PMC article.
Evaluation of phthalazinone phosphodiesterase inhibitors with improved activity and selectivity against Trypanosoma cruzi.
De Araújo JS, da Silva PB, Batista MM, Peres RB, Cardoso-Santos C, Kalejaiye TD, Munday JC, De Heuvel E, Sterk GJ, Augustyns K, Salado IG, Matheeussen A, De Esch I, De Koning HP, Leurs R, Maes L, Soeiro MNC. De Araújo JS, et al. Among authors: da silva pb. J Antimicrob Chemother. 2020 Apr 1;75(4):958-967. doi: 10.1093/jac/dkz516. J Antimicrob Chemother. 2020. PMID: 31860098
The efficacy of novel arylimidamides against Trypanosoma cruzi in vitro.
DA Silva CF, Daliry A, DA Silva PB, Akay S, Banerjee M, Farahat AA, Fisher MK, Hu L, Kumar A, Liu Z, Stephens CE, Boykin DW, Correia Soeiro MD. DA Silva CF, et al. Among authors: da silva pb. Parasitology. 2011 Dec;138(14):1863-9. doi: 10.1017/S0031182011001429. Epub 2011 Sep 9. Parasitology. 2011. PMID: 21902869
Identification of Pyrazolo[3,4-e][1,4]thiazepin based CYP51 inhibitors as potential Chagas disease therapeutic alternative: In vitro and in vivo evaluation, binding mode prediction and SAR exploration.
Ferreira de Almeida Fiuza L, Peres RB, Simões-Silva MR, da Silva PB, Batista DDGJ, da Silva CF, Nefertiti Silva da Gama A, Krishna Reddy TR, Soeiro MNC. Ferreira de Almeida Fiuza L, et al. Among authors: da silva cf, da silva pb. Eur J Med Chem. 2018 Apr 10;149:257-268. doi: 10.1016/j.ejmech.2018.02.020. Epub 2018 Feb 23. Eur J Med Chem. 2018. PMID: 29501946 Free article.
New 1,2,3-triazole-based analogues of benznidazole for use against Trypanosoma cruzi infection: In vitro and in vivo evaluations.
Leite DI, Fontes FV, Bastos MM, Hoelz LVB, Bianco MDCAD, de Oliveira AP, da Silva PB, da Silva CF, Batista DDGJ, da Gama ANS, Peres RB, Villar JDF, Soeiro MNC, Boechat N. Leite DI, et al. Among authors: da gama ans, da silva cf, da silva pb. Chem Biol Drug Des. 2018 Sep;92(3):1670-1682. doi: 10.1111/cbdd.13333. Epub 2018 Jun 13. Chem Biol Drug Des. 2018. PMID: 29745048
Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2-Benzyl-5-nitroindazole-Derived Amines.
Fonseca-Berzal C, Ibáñez-Escribano A, Vela N, Cumella J, Nogal-Ruiz JJ, Escario JA, da Silva PB, Batista MM, Soeiro MNC, Sifontes-Rodríguez S, Meneses-Marcel A, Gómez-Barrio A, Arán VJ. Fonseca-Berzal C, et al. Among authors: da silva pb. ChemMedChem. 2018 Jun 20;13(12):1246-1259. doi: 10.1002/cmdc.201800084. Epub 2018 May 22. ChemMedChem. 2018. PMID: 29624912
96 results