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Dapsone-induced methemoglobinemia and hemolysis in a woman without G6PD deficiency presenting with idiopathic urticaria.
Hu Y, Geere M, Awan M, Leavitt AD, Brown LE, Pearson HJ, Gandelman JS, Kogan SC. Hu Y, et al. Hematology. 2022 Dec;27(1):1253-1258. doi: 10.1080/16078454.2022.2149943. Hematology. 2022. PMID: 36444994 Free PMC article.
BACKGROUND: The appearance of bite cells associated with methemoglobinemia can be caused by oxidizing drugs such as dapsone in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency or high drug serum levels. ...During the patient's hospital course …
BACKGROUND: The appearance of bite cells associated with methemoglobinemia can be caused by oxidizing drugs such as dapsone in …
Methemoglobinemia induced by dapsone, hydroxychloroquine, and rifampin combination for post-treatment Lyme disease syndrome: A case report.
Worden J, Baumeister T, Stogner S, Henin N, Stern RA. Worden J, et al. J Am Pharm Assoc (2003). 2026 Mar-Apr;66(2):103009. doi: 10.1016/j.japh.2025.103009. Epub 2025 Dec 18. J Am Pharm Assoc (2003). 2026. PMID: 41421419
Analysis of peripheral blood smear revealed oxidative hemolysis, indicating medication-induced methemoglobinemia. Glucose-6-phosphate-dehydrogenase (G6PD) testing was ordered to assess for G6PD deficiency, as this is a known risk factor for methemoglobinem
Analysis of peripheral blood smear revealed oxidative hemolysis, indicating medication-induced methemoglobinemia. Glucose-6-phosphate …