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A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice.
de Alwis R, Gan ES, Chen S, Leong YS, Tan HC, Zhang SL, Yau C, Low JGH, Kalimuddin S, Matsuda D, Allen EC, Hartman P, Park KJ, Alayyoubi M, Bhaskaran H, Dukanovic A, Bao Y, Clemente B, Vega J, Roberts S, Gonzalez JA, Sablad M, Yelin R, Taylor W, Tachikawa K, Parker S, Karmali P, Davis J, Sullivan BM, Sullivan SM, Hughes SG, Chivukula P, Ooi EE. de Alwis R, et al. Mol Ther. 2021 Jun 2;29(6):1970-1983. doi: 10.1016/j.ymthe.2021.04.001. Epub 2021 Apr 5. Mol Ther. 2021. PMID: 33823303 Free PMC article.
Antibody sugars are bittersweet.
de Alwis R, Ooi EE. de Alwis R, et al. Science. 2021 Jun 4;372(6546):1041-1042. doi: 10.1126/science.abj0435. Science. 2021. PMID: 34083476 No abstract available.
Adverse effects following anti-COVID-19 vaccination with mRNA-based BNT162b2 are alleviated by altering the route of administration and correlate with baseline enrichment of T and NK cell genes.
Syenina A, Gan ES, Toh JZN, de Alwis R, Lin LZ, Tham CYL, Yee JX, Leong YS, Sam H, Cheong C, Teh YE, Wee ILE, Ng DHL, Chan KR, Sim JXY, Kalimuddin S, Ong EZ, Low JG, Ooi EE. Syenina A, et al. Among authors: de alwis r. PLoS Biol. 2022 May 31;20(5):e3001643. doi: 10.1371/journal.pbio.3001643. eCollection 2022 May. PLoS Biol. 2022. PMID: 35639676 Free PMC article.
BNT162b2 mRNA Vaccine-Induced Immune Response in Oral Fluids and Serum.
Seneviratne CJ, Balan P, de Alwis R, Udawatte NS, Herath T, Toh JZN, Tin GB, Ooi EE, Hong JLG, Ying JSX. Seneviratne CJ, et al. Among authors: de alwis r. Int Dent J. 2023 Jun;73(3):435-442. doi: 10.1016/j.identj.2022.09.005. Epub 2022 Nov 17. Int Dent J. 2023. PMID: 36402577 Free PMC article.
52 results