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Ubiquitination of E3 ligases: self-regulation of the ubiquitin system via proteolytic and non-proteolytic mechanisms.
de Bie P, Ciechanover A. de Bie P, et al. Cell Death Differ. 2011 Sep;18(9):1393-402. doi: 10.1038/cdd.2011.16. Epub 2011 Mar 4. Cell Death Differ. 2011. PMID: 21372847 Free PMC article. Review.
RING1B ubiquitination and stability are regulated by ARF.
de Bie P, Ciechanover A. de Bie P, et al. Biochem Biophys Res Commun. 2012 Sep 14;426(1):49-53. doi: 10.1016/j.bbrc.2012.08.030. Epub 2012 Aug 13. Biochem Biophys Res Commun. 2012. PMID: 22910419
PRAJA1 is a ubiquitin ligase for the polycomb repressive complex 2 proteins.
Zoabi M, Sadeh R, de Bie P, Marquez VE, Ciechanover A. Zoabi M, et al. Among authors: de bie p. Biochem Biophys Res Commun. 2011 May 13;408(3):393-8. doi: 10.1016/j.bbrc.2011.04.025. Epub 2011 Apr 12. Biochem Biophys Res Commun. 2011. PMID: 21513699
Regulation of the polycomb protein Ring1B by self-ubiquitination or by E6-AP may have implications to the pathogenesis of Angelman syndrome.
Zaaroor-Regev D, de Bie P, Scheffner M, Noy T, Shemer R, Heled M, Stein I, Pikarsky E, Ciechanover A. Zaaroor-Regev D, et al. Among authors: de bie p. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6788-93. doi: 10.1073/pnas.1003108107. Epub 2010 Mar 29. Proc Natl Acad Sci U S A. 2010. PMID: 20351251 Free PMC article.
Regulation of the Polycomb protein RING1B ubiquitination by USP7.
de Bie P, Zaaroor-Regev D, Ciechanover A. de Bie P, et al. Biochem Biophys Res Commun. 2010 Sep 24;400(3):389-95. doi: 10.1016/j.bbrc.2010.08.082. Epub 2010 Aug 26. Biochem Biophys Res Commun. 2010. PMID: 20800574
Characterization of COMMD protein-protein interactions in NF-kappaB signalling.
de Bie P, van de Sluis B, Burstein E, Duran KJ, Berger R, Duckett CS, Wijmenga C, Klomp LW. de Bie P, et al. Biochem J. 2006 Aug 15;398(1):63-71. doi: 10.1042/BJ20051664. Biochem J. 2006. PMID: 16573520 Free PMC article.
Mechanism of inhibition of the human immunodeficiency virus type 1 by the oxygen radical generating agent bleomycin.
Georgiou NA, van der Bruggen T, Oudshoorn M, de Bie P, Jansen CA, Nottet HS, Marx JJ, van Asbeck BS. Georgiou NA, et al. Among authors: de bie p. Antiviral Res. 2004 Aug;63(2):97-106. doi: 10.1016/j.antiviral.2004.03.003. Antiviral Res. 2004. PMID: 15302138
Liver-specific Commd1 knockout mice are susceptible to hepatic copper accumulation.
Vonk WI, Bartuzi P, de Bie P, Kloosterhuis N, Wichers CG, Berger R, Haywood S, Klomp LW, Wijmenga C, van de Sluis B. Vonk WI, et al. Among authors: de bie p. PLoS One. 2011;6(12):e29183. doi: 10.1371/journal.pone.0029183. Epub 2011 Dec 22. PLoS One. 2011. PMID: 22216203 Free PMC article.
The copper-transporting capacity of ATP7A mutants associated with Menkes disease is ameliorated by COMMD1 as a result of improved protein expression.
Vonk WI, de Bie P, Wichers CG, van den Berghe PV, van der Plaats R, Berger R, Wijmenga C, Klomp LW, van de Sluis B. Vonk WI, et al. Among authors: de bie p. Cell Mol Life Sci. 2012 Jan;69(1):149-63. doi: 10.1007/s00018-011-0743-1. Epub 2011 Jun 11. Cell Mol Life Sci. 2012. PMID: 21667063 Free PMC article.
Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B.
de Bie P, van de Sluis B, Burstein E, van de Berghe PV, Muller P, Berger R, Gitlin JD, Wijmenga C, Klomp LW. de Bie P, et al. Gastroenterology. 2007 Oct;133(4):1316-26. doi: 10.1053/j.gastro.2007.07.020. Epub 2007 Jul 25. Gastroenterology. 2007. PMID: 17919502 Free PMC article.
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