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Rate and determinants of 10-year persistence with antihypertensive drugs.
Van Wijk BL, Klungel OH, Heerdink ER, de Boer A. Van Wijk BL, et al. J Hypertens. 2005 Nov;23(11):2101-7. doi: 10.1097/01.hjh.0000187261.40190.2e. J Hypertens. 2005. PMID: 16208154
DESIGN: A retrospective cohort study. SETTING: The PHARMO record linkage system containing drug dispensing records from community pharmacies and linked hospital discharge records of approximately 950 000 subjects. ...RESULTS: Among a total of 2325 patients who start …
DESIGN: A retrospective cohort study. SETTING: The PHARMO record linkage system containing drug dispensing records from community pha …
Benzodiazepines and the risk of falling leading to femur fractures. Dosage more important than elimination half-life.
Herings RM, Stricker BH, de Boer A, Bakker A, Sturmans F. Herings RM, et al. Arch Intern Med. 1995 Sep 11;155(16):1801-7. Arch Intern Med. 1995. PMID: 7654115
BACKGROUND: In the past decade, the use of benzodiazepines has been identified as a major independent risk factor for accidental falls. ...METHODS: A 1:3 age-, sex-, and pharmacy-matched case-control study was performed using data from a Dutch record linkage …
BACKGROUND: In the past decade, the use of benzodiazepines has been identified as a major independent risk factor for accidental fall …
A rapid method to estimate the incidence rate and prevalence of insulin-dependent diabetes mellitus in children 0-19 years of age.
Herings RM, de Boer A, Stricker BH, Bakker A, Sturmans F. Herings RM, et al. Pharm World Sci. 1995 Jan 27;17(1):17-9. doi: 10.1007/BF01875553. Pharm World Sci. 1995. PMID: 7719274
The data were obtained from pharmacy, patient-based, drug dispensing histories in a well-defined population encompassing 257,113 individuals in the Netherlands. ...DISCUSSION: The incidence rate is comparable to that found in a large, national survey among all paedi …
The data were obtained from pharmacy, patient-based, drug dispensing histories in a well-defined population encompassing 257,113 indi …
Hypoglycaemia associated with use of inhibitors of angiotensin converting enzyme.
Herings RM, de Boer A, Stricker BH, Leufkens HG, Porsius A. Herings RM, et al. Lancet. 1995 May 13;345(8959):1195-8. doi: 10.1016/s0140-6736(95)91988-0. Lancet. 1995. PMID: 7739305
To test this hypothesis we carried out a nested case-control study, using data in the Dutch PHARMO system (1986-92), among diabetic patients treated with insulin or with oral antidiabetic drugs, who were admitted to hospital with hypoglycaemia. ...With adjustment for a
To test this hypothesis we carried out a nested case-control study, using data in the Dutch PHARMO system (1986-92), among diabetic p …
Current use of thiazide diuretics and prevention of femur fractures.
Herings RM, Stricker BH, de Boer A, Bakker A, Sturmans F, Stergachis A. Herings RM, et al. J Clin Epidemiol. 1996 Jan;49(1):115-9. doi: 10.1016/0895-4356(95)00552-8. J Clin Epidemiol. 1996. PMID: 8598504
A case control study of a defined population from The Netherlands was performed to evaluate the risk of femur fractures associated with the use of thiazide diuretics. ...
A case control study of a defined population from The Netherlands was performed to evaluate the risk of femur fractures associ
Non-compliance in elderly people: evaluation of risk factors by longitudinal data analysis.
Lau HS, Beuning KS, Postma-Lim E, Klein-Beernink L, de Boer A, Porsius AJ. Lau HS, et al. Pharm World Sci. 1996 Apr;18(2):63-8. doi: 10.1007/BF00579707. Pharm World Sci. 1996. PMID: 8739259
Of these subjects, 37 were residents of a home for the elderly, 40 were community-dwelling elderly who needed to be visited regularly by a district nurse, and 80 were community-dwelling elderly who did not need to be visited by a district nurse. ...Compliance …
Of these subjects, 37 were residents of a home for the elderly, 40 were community-dwelling elderly who needed to be visited regularly …
Validation of pharmacy records in drug exposure assessment.
Lau HS, de Boer A, Beuning KS, Porsius A. Lau HS, et al. J Clin Epidemiol. 1997 May;50(5):619-25. doi: 10.1016/s0895-4356(97)00040-1. J Clin Epidemiol. 1997. PMID: 9180655
Two employed a fixed time window of 30 and 90 days, respectively, and the third method was based on the calculated duration of use of a prescription ("legend time"). ...We conclude that computerized pharmacy records can be a reliable source of the true drug e …
Two employed a fixed time window of 30 and 90 days, respectively, and the third method was based on the calculated duration of use of …
Sex differences in the pharmacological treatment of hypertension: a review of population-based studies.
Klungel OH, de Boer A, Paes AH, Seidell JC, Bakker A. Klungel OH, et al. J Hypertens. 1997 Jun;15(6):591-600. doi: 10.1097/00004872-199715060-00004. J Hypertens. 1997. PMID: 9218177 Review.
DATA IDENTIFICATION: A secondary analysis of data from 46 population-based studies in 22 countries on the prevalence of pharmacologically treated hypertension was conducted to estimate sex ratios for the prevalence of drug treatment for hypertension. ...
DATA IDENTIFICATION: A secondary analysis of data from 46 population-based studies in 22 countries on the prevalence of pharmacologic …
Undertreatment of hypertension in a population-based study in The Netherlands.
Klungel OH, de Boer A, Paes AH, Seidell JC, Nagelkerke NJ, Bakker A. Klungel OH, et al. J Hypertens. 1998 Sep;16(9):1371-8. doi: 10.1097/00004872-199816090-00018. J Hypertens. 1998. PMID: 9746124
OBJECTIVE: To estimate the level of undertreatment of hypertension in a population-based study by taking into account the co-existence of additional cardiovascular risk factors in untreated hypertensives, uncontrolled blood pressure among pharmacologically treated hyperten …
OBJECTIVE: To estimate the level of undertreatment of hypertension in a population-based study by taking into account the co-existenc …
Sex differences in antihypertensive drug use: determinants of the choice of medication for hypertension.
Klungel OH, de Boer A, Paes AH, Seidell JC, Bakker A. Klungel OH, et al. J Hypertens. 1998 Oct;16(10):1545-53. doi: 10.1097/00004872-199816100-00021. J Hypertens. 1998. PMID: 9814628
Among those on monotherapy for hypertension, women were less likely than men to be using a beta-blocker [prevalence odds ratio (POR), female/male=0.34; 95% confidence interval (CI) 0.24-0.47], a calcium antagonist (POR=0.27, 95% CI 0.15-0.48) or an angiotensin conve …
Among those on monotherapy for hypertension, women were less likely than men to be using a beta-blocker [prevalence odds ratio (POR), …
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