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Zero-order rectal delivery of theophylline in man with an osmotic system.
de Leede LG, de Boer AG, van Velzen SL, Breimer DD. de Leede LG, et al. J Pharmacokinet Biopharm. 1982 Oct;10(5):525-37. doi: 10.1007/BF01059035. J Pharmacokinet Biopharm. 1982. PMID: 7166736
Rectal infusion of the model drug antipyrine with an osmotic delivery system.
de Leede LG, de Boer AG, Breimer DD. de Leede LG, et al. Biopharm Drug Dispos. 1981 Apr-Jun;2(2):131-6. doi: 10.1002/bdd.2510020205. Biopharm Drug Dispos. 1981. PMID: 7248477
First-pass elimination of salicylamide in man following oral and rectal administration.
de Boer AG, Breimer DD, Gubbens-Stibbe JM, Bosma A. de Boer AG, et al. Biopharm Drug Dispos. 1983 Oct-Dec;4(4):321-30. doi: 10.1002/bdd.2510040404. Biopharm Drug Dispos. 1983. PMID: 6689276 Clinical Trial.
Rectal drug administration: clinical pharmacokinetic considerations.
de Boer AG, Moolenaar F, de Leede LG, Breimer DD. de Boer AG, et al. Clin Pharmacokinet. 1982 Jul-Aug;7(4):285-311. doi: 10.2165/00003088-198207040-00002. Clin Pharmacokinet. 1982. PMID: 6126289 Review.
Complete rectal absorption of theophylline in rats without absorption enhancer.
van Hoogdalem EJ, de Boer AG, Breimer DD. van Hoogdalem EJ, et al. J Pharm Sci. 1986 Sep;75(9):917-8. doi: 10.1002/jps.2600750921. J Pharm Sci. 1986. PMID: 3783464 No abstract available.
Synthetic hydrogels as drug delivery systems.
Roorda WE, Boddé HE, De Boer AG, Bouwstra JA, Junginer HE. Roorda WE, et al. Pharm Weekbl Sci. 1986 Jun 20;8(3):165-89. doi: 10.1007/BF01959775. Pharm Weekbl Sci. 1986. PMID: 3526277 Review.
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