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Irinotecan (CPT-11) metabolism and disposition in cancer patients.
Sparreboom A, de Jonge MJ, de Bruijn P, Brouwer E, Nooter K, Loos WJ, van Alphen RJ, Mathijssen RH, Stoter G, Verweij J. Sparreboom A, et al. Among authors: de bruijn p, de jonge mj. Clin Cancer Res. 1998 Nov;4(11):2747-54. Clin Cancer Res. 1998. PMID: 9829738 Clinical Trial.
Modulation of irinotecan metabolism by ketoconazole.
Kehrer DF, Mathijssen RH, Verweij J, de Bruijn P, Sparreboom A. Kehrer DF, et al. Among authors: de bruijn p. J Clin Oncol. 2002 Jul 15;20(14):3122-9. doi: 10.1200/JCO.2002.08.177. J Clin Oncol. 2002. PMID: 12118026 Clinical Trial.
Effects of St. John's wort on irinotecan metabolism.
Mathijssen RH, Verweij J, de Bruijn P, Loos WJ, Sparreboom A. Mathijssen RH, et al. Among authors: de bruijn p. J Natl Cancer Inst. 2002 Aug 21;94(16):1247-9. doi: 10.1093/jnci/94.16.1247. J Natl Cancer Inst. 2002. PMID: 12189228 Free article. Clinical Trial.
Phase I and pharmacokinetic study of irinotecan in combination with R115777, a farnesyl protein transferase inhibitor.
Sparreboom A, Kehrer DF, Mathijssen RH, Xie R, de Jonge MJ, de Bruijn P, Planting AS, Eskens FA, Verheij C, de Heus G, Klaren A, Zhang S, Verhaeghe T, Palmer PA, Verweij J. Sparreboom A, et al. Among authors: de bruijn p, de heus g, de jonge mj. Br J Cancer. 2004 Apr 19;90(8):1508-15. doi: 10.1038/sj.bjc.6601732. Br J Cancer. 2004. PMID: 15083177 Free PMC article. Clinical Trial.
141 results