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T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice.
Bazioti V, La Rose AM, Maassen S, Bianchi F, de Boer R, Halmos B, Dabral D, Guilbaud E, Flohr-Svendsen A, Groenen AG, Marmolejo-Garza A, Koster MH, Kloosterhuis NJ, Havinga R, Pranger AT, Langelaar-Makkinje M, de Bruin A, van de Sluis B, Kohan AB, Yvan-Charvet L, van den Bogaart G, Westerterp M. Bazioti V, et al. Among authors: de boer r, de bruin a. Nat Commun. 2022 Jul 1;13(1):3799. doi: 10.1038/s41467-022-31135-4. Nat Commun. 2022. PMID: 35778407 Free PMC article.
Tumor necrosis factor receptor 1 gain-of-function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model.
Aparicio-Vergara M, Hommelberg PP, Schreurs M, Gruben N, Stienstra R, Shiri-Sverdlov R, Kloosterhuis NJ, de Bruin A, van de Sluis B, Koonen DP, Hofker MH. Aparicio-Vergara M, et al. Among authors: de bruin a. Hepatology. 2013 Feb;57(2):566-76. doi: 10.1002/hep.26046. Epub 2013 Jan 10. Hepatology. 2013. PMID: 22941955
Increased hepatic CD36 expression with age is associated with enhanced susceptibility to nonalcoholic fatty liver disease.
Sheedfar F, Sung MM, Aparicio-Vergara M, Kloosterhuis NJ, Miquilena-Colina ME, Vargas-Castrillón J, Febbraio M, Jacobs RL, de Bruin A, Vinciguerra M, García-Monzón C, Hofker MH, Dyck JR, Koonen DP. Sheedfar F, et al. Among authors: de bruin a. Aging (Albany NY). 2014 Apr;6(4):281-95. doi: 10.18632/aging.100652. Aging (Albany NY). 2014. PMID: 24751397 Free PMC article.
Chemokine-like receptor 1 deficiency does not affect the development of insulin resistance and nonalcoholic fatty liver disease in mice.
Gruben N, Aparicio Vergara M, Kloosterhuis NJ, van der Molen H, Stoelwinder S, Youssef S, de Bruin A, Delsing DJ, Kuivenhoven JA, van de Sluis B, Hofker MH, Koonen DP. Gruben N, et al. Among authors: de bruin a. PLoS One. 2014 Apr 29;9(4):e96345. doi: 10.1371/journal.pone.0096345. eCollection 2014. PLoS One. 2014. PMID: 24781986 Free PMC article.
A cell-type-specific role for murine Commd1 in liver inflammation.
Bartuzi P, Wijshake T, Dekker DC, Fedoseienko A, Kloosterhuis NJ, Youssef SA, Li H, Shiri-Sverdlov R, Kuivenhoven JA, de Bruin A, Burstein E, Hofker MH, van de Sluis B. Bartuzi P, et al. Among authors: de bruin a. Biochim Biophys Acta. 2014 Nov;1842(11):2257-65. doi: 10.1016/j.bbadis.2014.06.035. Epub 2014 Jul 27. Biochim Biophys Acta. 2014. PMID: 25072958 Free PMC article.
NF-κB p65 serine 467 phosphorylation sensitizes mice to weight gain and TNFα-or diet-induced inflammation.
Riedlinger T, Dommerholt MB, Wijshake T, Kruit JK, Huijkman N, Dekker D, Koster M, Kloosterhuis N, Koonen DPY, de Bruin A, Baker D, Hofker MH, van Deursen J, Jonker JW, Schmitz ML, van de Sluis B. Riedlinger T, et al. Among authors: de bruin a. Biochim Biophys Acta Mol Cell Res. 2017 Oct;1864(10):1785-1798. doi: 10.1016/j.bbamcr.2017.07.005. Epub 2017 Jul 16. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28723419 Free article.
A Proinflammatory Gut Microbiota Increases Systemic Inflammation and Accelerates Atherosclerosis.
Brandsma E, Kloosterhuis NJ, Koster M, Dekker DC, Gijbels MJJ, van der Velden S, Ríos-Morales M, van Faassen MJR, Loreti MG, de Bruin A, Fu J, Kuipers F, Bakker BM, Westerterp M, de Winther MPJ, Hofker MH, van de Sluis B, Koonen DPY. Brandsma E, et al. Among authors: de winther mpj, de bruin a. Circ Res. 2019 Jan 4;124(1):94-100. doi: 10.1161/CIRCRESAHA.118.313234. Circ Res. 2019. PMID: 30582442 Free PMC article.
LED-phototherapy does not induce oxidative DNA damage in hyperbilirubinemic Gunn rats.
van der Schoor LWE, Hulzebos CV, van Faassen MH, Kema IP, de Bruin A, Havinga R, Koster M, Youssef SA, Bongiovanni L, Jonker JW, Verkade HJ. van der Schoor LWE, et al. Among authors: de bruin a. Pediatr Res. 2019 Jun;85(7):1041-1047. doi: 10.1038/s41390-019-0367-y. Epub 2019 Mar 9. Pediatr Res. 2019. PMID: 30851724
E2F7 Is a Potent Inhibitor of Liver Tumor Growth in Adult Mice.
Moreno E, Toussaint MJM, van Essen SC, Bongiovanni L, van Liere EA, Koster MH, Yuan R, van Deursen JM, Westendorp B, de Bruin A. Moreno E, et al. Among authors: de bruin a. Hepatology. 2021 Jan;73(1):303-317. doi: 10.1002/hep.31259. Hepatology. 2021. PMID: 32259305 Free PMC article.
380 results