de Bruin NM - Search Results

1

SLV330, a cannabinoid CB1 receptor antagonist, ameliorates deficits in the T-maze, object recognition and Social Recognition Tasks in rodents.

de Bruin NM, Prickaerts J, Lange JH, Akkerman S, Andriambeloson E, de Haan M, Wijnen J, van Drimmelen M, Hissink E, Heijink L, Kruse CG. de Bruin NM, et al. Among authors: de haan m. Neurobiol Learn Mem. 2010 May;93(4):522-31. doi: 10.1016/j.nlm.2010.01.010. Epub 2010 Feb 2. Neurobiol Learn Mem. 2010. PMID: 20132903

2

The selective 5-HT6 receptor antagonist SLV has putative cognitive- and social interaction enhancing properties in rodent models of cognitive impairment.

de Bruin NMWJ, van Loevezijn A, Wicke KM, de Haan M, Venhorst J, Lange JHM, de Groote L, van der Neut MAW, Prickaerts J, Andriambeloson E, Foley AG, van Drimmelen M, van der Wetering M, Kruse CG. de Bruin NMWJ, et al. Neurobiol Learn Mem. 2016 Sep;133:100-117. doi: 10.1016/j.nlm.2016.06.020. Epub 2016 Jun 21. Neurobiol Learn Mem. 2016. PMID: 27344942

3

SLV330, a cannabinoid CB(1) receptor antagonist, attenuates ethanol and nicotine seeking and improves inhibitory response control in rats.

de Bruin NM, Lange JH, Kruse CG, Herremans AH, Schoffelmeer AN, van Drimmelen M, De Vries TJ. de Bruin NM, et al. Among authors: de vries tj. Behav Brain Res. 2011 Mar 1;217(2):408-15. doi: 10.1016/j.bbr.2010.11.013. Epub 2010 Nov 11. Behav Brain Res. 2011. PMID: 21074574

4

Two novel 5-HT6 receptor antagonists ameliorate scopolamine-induced memory deficits in the object recognition and object location tasks in Wistar rats.

de Bruin NM, Prickaerts J, van Loevezijn A, Venhorst J, de Groote L, Houba P, Reneerkens O, Akkerman S, Kruse CG. de Bruin NM, et al. Neurobiol Learn Mem. 2011 Sep;96(2):392-402. doi: 10.1016/j.nlm.2011.06.015. Epub 2011 Jul 3. Neurobiol Learn Mem. 2011. PMID: 21757018

5

Cannabinoid antagonist SLV326 induces convulsive seizures and changes in the interictal EEG in rats.

Perescis MF, de Bruin N, Heijink L, Kruse C, Vinogradova L, Lüttjohann A, van Luijtelaar G, van Rijn CM. Perescis MF, et al. PLoS One. 2017 Feb 2;12(2):e0165363. doi: 10.1371/journal.pone.0165363. eCollection 2017. PLoS One. 2017. PMID: 28151935 Free PMC article.

6

5-HT6 Receptor Antagonists: Potential Efficacy for the Treatment of Cognitive Impairment in Schizophrenia.

de Bruin NM, Kruse CG. de Bruin NM, et al. Curr Pharm Des. 2015;21(26):3739-59. doi: 10.2174/1381612821666150605112105. Curr Pharm Des. 2015. PMID: 26044973 Review.

7

A novel highly selective 5-HT6 receptor antagonist attenuates ethanol and nicotine seeking but does not affect inhibitory response control in Wistar rats.

de Bruin NMWJ, McCreary AC, van Loevezijn A, de Vries TJ, Venhorst J, van Drimmelen M, Kruse CG. de Bruin NMWJ, et al. Behav Brain Res. 2013 Jan 1;236(1):157-165. doi: 10.1016/j.bbr.2012.08.048. Epub 2012 Sep 4. Behav Brain Res. 2013. PMID: 22974550

8

Effects of risperidone, clozapine and the 5-HT6 antagonist GSK-742457 on PCP-induced deficits in reversal learning in the two-lever operant task in male Sprague Dawley rats.

de Bruin NM, van Drimmelen M, Kops M, van Elk J, Wetering MM, Schwienbacher I. de Bruin NM, et al. Behav Brain Res. 2013 May 1;244:15-28. doi: 10.1016/j.bbr.2013.01.035. Epub 2013 Feb 4. Behav Brain Res. 2013. PMID: 23384714

9

Biophysical and physicochemical methods differentiate highly ligand-efficient human D-amino acid oxidase inhibitors.

Lange JH, Venhorst J, van Dongen MJ, Frankena J, Bassissi F, de Bruin NM, den Besten C, de Beer SB, Oostenbrink C, Markova N, Kruse CG. Lange JH, et al. Among authors: de bruin nm. Eur J Med Chem. 2011 Oct;46(10):4808-19. doi: 10.1016/j.ejmech.2011.04.023. Epub 2011 May 13. Eur J Med Chem. 2011. PMID: 21880399

10

Optimization of N'-(arylsulfonyl)pyrazoline-1-carboxamidines by exploiting a novel interaction site in the 5-HT6 antagonistic binding pocket.

van Loevezijn A, Venhorst J, Iwema Bakker WI, Lange JHM, de Looff W, Henzen R, de Vries J, van de Woestijne RP, den Hartog AP, Verhoog S, van der Neut MAW, de Bruin NMWJ, Kruse CG. van Loevezijn A, et al. Among authors: de bruin nmwj. Bioorg Med Chem Lett. 2016 Mar 15;26(6):1605-1611. doi: 10.1016/j.bmcl.2016.02.001. Epub 2016 Feb 2. Bioorg Med Chem Lett. 2016. PMID: 26876931

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