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Mitochondrial biogenesis and healthy aging.
López-Lluch G, Irusta PM, Navas P, de Cabo R. López-Lluch G, et al. Exp Gerontol. 2008 Sep;43(9):813-9. doi: 10.1016/j.exger.2008.06.014. Epub 2008 Jul 9. Exp Gerontol. 2008. PMID: 18662766 Free PMC article. Review.
Dietary fat modifies mitochondrial and plasma membrane apoptotic signaling in skeletal muscle of calorie-restricted mice.
López-Domínguez JA, Khraiwesh H, González-Reyes JA, López-Lluch G, Navas P, Ramsey JJ, de Cabo R, Burón MI, Villalba JM. López-Domínguez JA, et al. Age (Dordr). 2013 Dec;35(6):2027-44. doi: 10.1007/s11357-012-9492-9. Epub 2012 Nov 20. Age (Dordr). 2013. PMID: 23179253 Free PMC article.
The importance of plasma membrane coenzyme Q in aging and stress responses.
Navas P, Villalba JM, de Cabo R. Navas P, et al. Mitochondrion. 2007 Jun;7 Suppl:S34-40. doi: 10.1016/j.mito.2007.02.010. Epub 2007 Mar 16. Mitochondrion. 2007. PMID: 17482527 Review.
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.
Gomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA. Gomes AP, et al. Cell. 2013 Dec 19;155(7):1624-38. doi: 10.1016/j.cell.2013.11.037. Cell. 2013. PMID: 24360282 Free PMC article.
Overexpression of CYB5R3 and NQO1, two NAD+ -producing enzymes, mimics aspects of caloric restriction.
Diaz-Ruiz A, Lanasa M, Garcia J, Mora H, Fan F, Martin-Montalvo A, Di Francesco A, Calvo-Rubio M, Salvador-Pascual A, Aon MA, Fishbein KW, Pearson KJ, Villalba JM, Navas P, Bernier M, de Cabo R. Diaz-Ruiz A, et al. Aging Cell. 2018 Aug;17(4):e12767. doi: 10.1111/acel.12767. Epub 2018 Apr 28. Aging Cell. 2018. PMID: 29706024 Free PMC article.
Spermidine to the rescue for an aging heart.
de Cabo R, Navas P. de Cabo R, et al. Nat Med. 2016 Dec 6;22(12):1389-1390. doi: 10.1038/nm.4243. Nat Med. 2016. PMID: 27923032 Free PMC article.
Mitochondrial protection by resveratrol.
Ungvari Z, Sonntag WE, de Cabo R, Baur JA, Csiszar A. Ungvari Z, et al. Exerc Sport Sci Rev. 2011 Jul;39(3):128-32. doi: 10.1097/JES.0b013e3182141f80. Exerc Sport Sci Rev. 2011. PMID: 21383627 Free PMC article. Review.
Mitochondrial metabolic reprogramming induced by calorie restriction.
Martin-Montalvo A, de Cabo R. Martin-Montalvo A, et al. Antioxid Redox Signal. 2013 Jul 20;19(3):310-20. doi: 10.1089/ars.2012.4866. Epub 2012 Oct 15. Antioxid Redox Signal. 2013. PMID: 22901095 Free PMC article. Review.
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