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Nicotinic acid effects on insulin sensitivity and hepatic lipid metabolism: an in vivo to in vitro study.
Blond E, Rieusset J, Alligier M, Lambert-Porcheron S, Bendridi N, Gabert L, Chetiveaux M, Debard C, Chauvin MA, Normand S, Roth H, de Gouville AC, Krempf M, Vidal H, Goudable J, Laville M; “Niacin” Study Group. Blond E, et al. Among authors: de gouville ac. Horm Metab Res. 2014 Jun;46(6):390-6. doi: 10.1055/s-0034-1372600. Epub 2014 May 7. Horm Metab Res. 2014. PMID: 24806747 Clinical Trial.
A Randomized, Placebo-Controlled Trial to Assess the Effects of 8 Weeks of Administration of GSK256073, a Selective GPR109A Agonist, on High-Density Lipoprotein Cholesterol in Subjects With Dyslipidemia.
Olson EJ, Mahar KM, Haws TF, Fossler MJ, Gao F, de Gouville AC, Sprecher DL, Lepore JJ. Olson EJ, et al. Among authors: de gouville ac. Clin Pharmacol Drug Dev. 2019 Oct;8(7):871-883. doi: 10.1002/cpdd.704. Epub 2019 Jul 3. Clin Pharmacol Drug Dev. 2019. PMID: 31268250 Clinical Trial.
Effects of Extended-Release Nicotinic Acid on Apolipoprotein (a) Kinetics in Hypertriglyceridemic Patients.
Croyal M, Ouguerram K, Passard M, Ferchaud-Roucher V, Chétiveaux M, Billon-Crossouard S, de Gouville AC, Lambert G, Krempf M, Nobécourt E. Croyal M, et al. Among authors: de gouville ac. Arterioscler Thromb Vasc Biol. 2015 Sep;35(9):2042-7. doi: 10.1161/ATVBAHA.115.305835. Epub 2015 Jul 9. Arterioscler Thromb Vasc Biol. 2015. PMID: 26160958 Clinical Trial.
Inhibition of ALK5 signaling induces physeal dysplasia in rats.
Frazier K, Thomas R, Scicchitano M, Mirabile R, Boyce R, Zimmerman D, Grygielko E, Nold J, DeGouville AC, Huet S, Laping N, Gellibert F. Frazier K, et al. Toxicol Pathol. 2007 Feb;35(2):284-95. doi: 10.1080/01926230701198469. Toxicol Pathol. 2007. PMID: 17366323
Discovery of 4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl}-N-(tetrahydro-2H- pyran-4-yl)benzamide (GW788388): a potent, selective, and orally active transforming growth factor-beta type I receptor inhibitor.
Gellibert F, de Gouville AC, Woolven J, Mathews N, Nguyen VL, Bertho-Ruault C, Patikis A, Grygielko ET, Laping NJ, Huet S. Gellibert F, et al. Among authors: de gouville ac. J Med Chem. 2006 Apr 6;49(7):2210-21. doi: 10.1021/jm0509905. J Med Chem. 2006. PMID: 16570917
13 results