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53 results
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Evaluation of the intestinal toxicity and transport of xenobiotics utilizing precision-cut slices.
Niu X, de Graaf IA, Groothuis GM. Niu X, et al. Among authors: de graaf ia. Xenobiotica. 2013 Jan;43(1):73-83. doi: 10.3109/00498254.2012.729870. Epub 2012 Oct 30. Xenobiotica. 2013. PMID: 23106567 Review.
Intercellular communication and cell proliferation in precision-cut rat liver slices: effect of medium composition and DDT.
de Graaf IA, Tajima O, Groten JP, Wolterbeek AP. de Graaf IA, et al. Cancer Lett. 2000 Jun 1;154(1):53-62. doi: 10.1016/s0304-3835(00)00377-3. Cancer Lett. 2000. PMID: 10799739
Assessment of some critical factors in the freezing technique for the cryopreservation of precision-cut rat liver slices.
Maas WJ, de Graaf IA, Schoen ED, Koster HJ, van de Sandt JJ, Groten JP. Maas WJ, et al. Among authors: de graaf ia. Cryobiology. 2000 May;40(3):250-63. doi: 10.1006/cryo.2000.2246. Cryobiology. 2000. PMID: 10860624
Cryopreservation of precision-cut tissue slices for application in drug metabolism research.
de Graaf IA, Koster HJ. de Graaf IA, et al. Toxicol In Vitro. 2003 Feb;17(1):1-17. doi: 10.1016/s0887-2333(02)00117-0. Toxicol In Vitro. 2003. PMID: 12537957 Review.
Prediction of whole-body metabolic clearance of drugs through the combined use of slices from rat liver, lung, kidney, small intestine and colon.
De Kanter R, Monshouwer M, Draaisma AL, De Jager MH, de Graaf IA, Proost JH, Meijer DK, Groothuis GM. De Kanter R, et al. Among authors: de jager mh, de graaf ia. Xenobiotica. 2004 Mar;34(3):229-41. doi: 10.1080/004982502000196758. Xenobiotica. 2004. PMID: 15204696
Characterization of rat small intestinal and colon precision-cut slices as an in vitro system for drug metabolism and induction studies.
van de Kerkhof EG, de Graaf IA, de Jager MH, Meijer DK, Groothuis GM. van de Kerkhof EG, et al. Among authors: de jager mh, de graaf ia. Drug Metab Dispos. 2005 Nov;33(11):1613-20. doi: 10.1124/dmd.105.005686. Epub 2005 Jul 28. Drug Metab Dispos. 2005. PMID: 16051733
Empirical validation of a rat in vitro organ slice model as a tool for in vivo clearance prediction.
de Graaf IA, de Kanter R, de Jager MH, Camacho R, Langenkamp E, van de Kerkhof EG, Groothuis GM. de Graaf IA, et al. Among authors: de jager mh, de kanter r. Drug Metab Dispos. 2006 Apr;34(4):591-9. doi: 10.1124/dmd.105.006726. Epub 2006 Jan 13. Drug Metab Dispos. 2006. PMID: 16415126
Innovative methods to study human intestinal drug metabolism in vitro: precision-cut slices compared with ussing chamber preparations.
van de Kerkhof EG, Ungell AL, Sjöberg AK, de Jager MH, Hilgendorf C, de Graaf IA, Groothuis GM. van de Kerkhof EG, et al. Among authors: de jager mh, de graaf ia. Drug Metab Dispos. 2006 Nov;34(11):1893-902. doi: 10.1124/dmd.106.011148. Epub 2006 Aug 16. Drug Metab Dispos. 2006. PMID: 16914511
Cryopreservation of rat precision-cut liver and kidney slices by rapid freezing and vitrification.
de Graaf IA, Draaisma AL, Schoeman O, Fahy GM, Groothuis GM, Koster HJ. de Graaf IA, et al. Cryobiology. 2007 Feb;54(1):1-12. doi: 10.1016/j.cryobiol.2006.09.002. Epub 2006 Dec 12. Cryobiology. 2007. PMID: 17166492
Induction of phase I and II drug metabolism in rat small intestine and colon in vitro.
van de Kerkhof EG, de Graaf IA, de Jager MH, Groothuis GM. van de Kerkhof EG, et al. Among authors: de jager mh, de graaf ia. Drug Metab Dispos. 2007 Jun;35(6):898-907. doi: 10.1124/dmd.106.014563. Epub 2007 Mar 7. Drug Metab Dispos. 2007. PMID: 17344336
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