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TRPV5: an ingeniously controlled calcium channel.
de Groot T, Bindels RJ, Hoenderop JG. de Groot T, et al. Kidney Int. 2008 Nov;74(10):1241-6. doi: 10.1038/ki.2008.320. Epub 2008 Jul 2. Kidney Int. 2008. PMID: 18596722 Review.
Extracellular pH dynamically controls cell surface delivery of functional TRPV5 channels.
Lambers TT, Oancea E, de Groot T, Topala CN, Hoenderop JG, Bindels RJ. Lambers TT, et al. Mol Cell Biol. 2007 Feb;27(4):1486-94. doi: 10.1128/MCB.01468-06. Epub 2006 Dec 18. Mol Cell Biol. 2007. PMID: 17178838 Free PMC article.
Parathyroid hormone activates TRPV5 via PKA-dependent phosphorylation.
de Groot T, Lee K, Langeslag M, Xi Q, Jalink K, Bindels RJ, Hoenderop JG. de Groot T, et al. J Am Soc Nephrol. 2009 Aug;20(8):1693-704. doi: 10.1681/ASN.2008080873. Epub 2009 May 7. J Am Soc Nephrol. 2009. PMID: 19423690 Free PMC article.
Molecular mechanisms of calmodulin action on TRPV5 and modulation by parathyroid hormone.
de Groot T, Kovalevskaya NV, Verkaart S, Schilderink N, Felici M, van der Hagen EA, Bindels RJ, Vuister GW, Hoenderop JG. de Groot T, et al. Mol Cell Biol. 2011 Jul;31(14):2845-53. doi: 10.1128/MCB.01319-10. Epub 2011 May 16. Mol Cell Biol. 2011. PMID: 21576356 Free PMC article.
Role of the transient receptor potential vanilloid 5 (TRPV5) protein N terminus in channel activity, tetramerization, and trafficking.
de Groot T, van der Hagen EA, Verkaart S, te Boekhorst VA, Bindels RJ, Hoenderop JG. de Groot T, et al. J Biol Chem. 2011 Sep 16;286(37):32132-9. doi: 10.1074/jbc.M111.226878. Epub 2011 Jul 27. J Biol Chem. 2011. PMID: 21795703 Free PMC article.
Hydrochlorothiazide attenuates lithium-induced nephrogenic diabetes insipidus independently of the sodium-chloride cotransporter.
Sinke AP, Kortenoeven ML, de Groot T, Baumgarten R, Devuyst O, Wetzels JF, Loffing J, Deen PM. Sinke AP, et al. Am J Physiol Renal Physiol. 2014 Mar 1;306(5):F525-33. doi: 10.1152/ajprenal.00617.2013. Epub 2013 Dec 18. Am J Physiol Renal Physiol. 2014. PMID: 24352504
Single-tubule RNA-Seq uncovers signaling mechanisms that defend against hyponatremia in SIADH.
Lee JW, Alsady M, Chou CL, de Groot T, Deen PMT, Knepper MA, Ecelbarger CM. Lee JW, et al. Kidney Int. 2018 Jan;93(1):128-146. doi: 10.1016/j.kint.2017.06.008. Epub 2017 Aug 23. Kidney Int. 2018. PMID: 28843412 Free PMC article.
Lithium in the Kidney: Friend and Foe?
Alsady M, Baumgarten R, Deen PM, de Groot T. Alsady M, et al. J Am Soc Nephrol. 2016 Jun;27(6):1587-95. doi: 10.1681/ASN.2015080907. Epub 2015 Nov 17. J Am Soc Nephrol. 2016. PMID: 26577775 Free PMC article. Review.
Inhibition of mitochondrial Na+-Ca2+ exchange restores agonist-induced ATP production and Ca2+ handling in human complex I deficiency.
Visch HJ, Rutter GA, Koopman WJ, Koenderink JB, Verkaart S, de Groot T, Varadi A, Mitchell KJ, van den Heuvel LP, Smeitink JA, Willems PH. Visch HJ, et al. J Biol Chem. 2004 Sep 24;279(39):40328-36. doi: 10.1074/jbc.M408068200. Epub 2004 Jul 21. J Biol Chem. 2004. PMID: 15269216
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