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APRIL modulates B and T cell immunity.
Stein JV, López-Fraga M, Elustondo FA, Carvalho-Pinto CE, Rodríguez D, Gómez-Caro R, De Jong J, Martínez-A C, Medema JP, Hahne M. Stein JV, et al. J Clin Invest. 2002 Jun;109(12):1587-98. doi: 10.1172/JCI15034. J Clin Invest. 2002. PMID: 12070306 Free PMC article.
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.
Vermeulen L, De Sousa E Melo F, van der Heijden M, Cameron K, de Jong JH, Borovski T, Tuynman JB, Todaro M, Merz C, Rodermond H, Sprick MR, Kemper K, Richel DJ, Stassi G, Medema JP. Vermeulen L, et al. Among authors: de sousa e melo f, de jong jh. Nat Cell Biol. 2010 May;12(5):468-76. doi: 10.1038/ncb2048. Epub 2010 Apr 25. Nat Cell Biol. 2010. PMID: 20418870
Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients.
de Sousa E Melo F, Colak S, Buikhuisen J, Koster J, Cameron K, de Jong JH, Tuynman JB, Prasetyanti PR, Fessler E, van den Bergh SP, Rodermond H, Dekker E, van der Loos CM, Pals ST, van de Vijver MJ, Versteeg R, Richel DJ, Vermeulen L, Medema JP. de Sousa E Melo F, et al. Among authors: de jong jh. Cell Stem Cell. 2011 Nov 4;9(5):476-85. doi: 10.1016/j.stem.2011.10.008. Cell Stem Cell. 2011. PMID: 22056143 Free article.
Mutations in the Ras-Raf Axis underlie the prognostic value of CD133 in colorectal cancer.
Kemper K, Versloot M, Cameron K, Colak S, de Sousa e Melo F, de Jong JH, Bleackley J, Vermeulen L, Versteeg R, Koster J, Medema JP. Kemper K, et al. Among authors: de sousa e melo f, de jong jh. Clin Cancer Res. 2012 Jun 1;18(11):3132-41. doi: 10.1158/1078-0432.CCR-11-3066. Epub 2012 Apr 10. Clin Cancer Res. 2012. PMID: 22496204
Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions.
De Sousa E Melo F, Wang X, Jansen M, Fessler E, Trinh A, de Rooij LP, de Jong JH, de Boer OJ, van Leersum R, Bijlsma MF, Rodermond H, van der Heijden M, van Noesel CJ, Tuynman JB, Dekker E, Markowetz F, Medema JP, Vermeulen L. De Sousa E Melo F, et al. Among authors: de jong jh, de boer oj, de rooij lp. Nat Med. 2013 May;19(5):614-8. doi: 10.1038/nm.3174. Epub 2013 Apr 14. Nat Med. 2013. PMID: 23584090
A multidimensional network approach reveals microRNAs as determinants of the mesenchymal colorectal cancer subtype.
Fessler E, Jansen M, De Sousa E Melo F, Zhao L, Prasetyanti PR, Rodermond H, Kandimalla R, Linnekamp JF, Franitza M, van Hooff SR, de Jong JH, Oppeneer SC, van Noesel CJ, Dekker E, Stassi G, Wang X, Medema JP, Vermeulen L. Fessler E, et al. Among authors: de sousa e melo f, de jong jh. Oncogene. 2016 Nov 17;35(46):6026-6037. doi: 10.1038/onc.2016.134. Epub 2016 May 9. Oncogene. 2016. PMID: 27157610 Free PMC article.
Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry.
Trinh A, Trumpi K, De Sousa E Melo F, Wang X, de Jong JH, Fessler E, Kuppen PJ, Reimers MS, Swets M, Koopman M, Nagtegaal ID, Jansen M, Hooijer GK, Offerhaus GJ, Kranenburg O, Punt CJ, Medema JP, Markowetz F, Vermeulen L. Trinh A, et al. Among authors: de sousa e melo f, de jong jh. Clin Cancer Res. 2017 Jan 15;23(2):387-398. doi: 10.1158/1078-0432.CCR-16-0680. Epub 2016 Jul 26. Clin Cancer Res. 2017. PMID: 27459899
Capturing colorectal cancer inter-tumor heterogeneity in patient-derived xenograft (PDX) models.
Prasetyanti PR, van Hooff SR, van Herwaarden T, de Vries N, Kalloe K, Rodermond H, van Leersum R, de Jong JH, Franitza M, Nürnberg P, Todaro M, Stassi G, Medema JP. Prasetyanti PR, et al. Among authors: de jong jh, de vries n. Int J Cancer. 2019 Jan 15;144(2):366-371. doi: 10.1002/ijc.31767. Epub 2018 Oct 22. Int J Cancer. 2019. PMID: 30151914 Free PMC article.
75 results