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Antitumor activity and safety of combination therapy with the Toll-like receptor 9 agonist IMO-2055, erlotinib, and bevacizumab in advanced or metastatic non-small cell lung cancer patients who have progressed following chemotherapy.
Smith DA, Conkling P, Richards DA, Nemunaitis JJ, Boyd TE, Mita AC, de La Bourdonnaye G, Wages D, Bexon AS. Smith DA, et al. Among authors: de la bourdonnaye g. Cancer Immunol Immunother. 2014 Aug;63(8):787-96. doi: 10.1007/s00262-014-1547-6. Epub 2014 Apr 27. Cancer Immunol Immunother. 2014. PMID: 24770667 Clinical Trial.
Open-label phase 1b study of FOLFIRI plus cetuximab plus IMO-2055 in patients with colorectal cancer who have progressed following chemotherapy for advanced or metastatic disease.
Chan E, Kwak EL, Hwang J, Heiskala M, de La Bourdonnaye G, Mita M. Chan E, et al. Among authors: de la bourdonnaye g. Cancer Chemother Pharmacol. 2015 Apr;75(4):701-9. doi: 10.1007/s00280-015-2682-2. Epub 2015 Jan 28. Cancer Chemother Pharmacol. 2015. PMID: 25627002 Clinical Trial.
Computer-aided engineering of stabilized fibroblast growth factor 21.
de La Bourdonnaye G, Ghazalova T, Fojtik P, Kutalkova K, Bednar D, Damborsky J, Rotrekl V, Stepankova V, Chaloupkova R. de La Bourdonnaye G, et al. Comput Struct Biotechnol J. 2024 Feb 7;23:942-951. doi: 10.1016/j.csbj.2024.02.001. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 38379823 Free PMC article.
Smoking and apolipoprotein levels: A meta-analysis of published data.
Kauss AR, Antunes M, de La Bourdonnaye G, Pouly S, Hankins M, Heremans A, van der Plas A. Kauss AR, et al. Among authors: de la bourdonnaye g. Toxicol Rep. 2022 May 17;9:1150-1171. doi: 10.1016/j.toxrep.2022.05.009. eCollection 2022. Toxicol Rep. 2022. PMID: 36518393 Free PMC article.
Impact of switching to a heat-not-burn tobacco product on CYP1A2 activity.
van der Plas A, Pouly S, Blanc N, Haziza C, de La Bourdonnaye G, Titz B, Hoeng J, Ivanov NV, Taranu B, Heremans A. van der Plas A, et al. Among authors: de la bourdonnaye g. Toxicol Rep. 2020 Oct 29;7:1480-1486. doi: 10.1016/j.toxrep.2020.10.017. eCollection 2020. Toxicol Rep. 2020. PMID: 33204648 Free PMC article.
Fibroblast Growth Factor 2 Protein Stability Provides Decreased Dependence on Heparin for Induction of FGFR Signaling and Alters ERK Signaling Dynamics.
Koledova Z, Sumbal J, Rabata A, de La Bourdonnaye G, Chaloupkova R, Hrdlickova B, Damborsky J, Stepankova V. Koledova Z, et al. Among authors: de la bourdonnaye g. Front Cell Dev Biol. 2019 Dec 12;7:331. doi: 10.3389/fcell.2019.00331. eCollection 2019. Front Cell Dev Biol. 2019. PMID: 31921844 Free PMC article.
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