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The hypocretins: setting the arousal threshold.
Sutcliffe JG, de Lecea L. Sutcliffe JG, et al. Among authors: de lecea l. Nat Rev Neurosci. 2002 May;3(5):339-49. doi: 10.1038/nrn808. Nat Rev Neurosci. 2002. PMID: 11988773 Review.
Four structurally distinct neuron-specific olfactomedin-related glycoproteins produced by differential promoter utilization and alternative mRNA splicing from a single gene.
Danielson PE, Forss-Petter S, Battenberg EL, deLecea L, Bloom FE, Sutcliffe JG. Danielson PE, et al. J Neurosci Res. 1994 Jul 1;38(4):468-78. doi: 10.1002/jnr.490380413. J Neurosci Res. 1994. PMID: 7932877
Isolation of clones of rat striatum-specific mRNAs by directional tag PCR subtraction.
Usui H, Falk JD, Dopazo A, de Lecea L, Erlander MG, Sutcliffe JG. Usui H, et al. Among authors: de lecea l. J Neurosci. 1994 Aug;14(8):4915-26. doi: 10.1523/JNEUROSCI.14-08-04915.1994. J Neurosci. 1994. PMID: 8046460 Free PMC article.
A cortical neuropeptide with neuronal depressant and sleep-modulating properties.
de Lecea L, Criado JR, Prospero-Garcia O, Gautvik KM, Schweitzer P, Danielson PE, Dunlop CL, Siggins GR, Henriksen SJ, Sutcliffe JG. de Lecea L, et al. Nature. 1996 May 16;381(6579):242-5. doi: 10.1038/381242a0. Nature. 1996. PMID: 8622767
Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin.
de Lecea L, Ruiz-Lozano P, Danielson PE, Peelle-Kirley J, Foye PE, Frankel WN, Sutcliffe JG. de Lecea L, et al. Genomics. 1997 Jun 15;42(3):499-506. doi: 10.1006/geno.1997.4763. Genomics. 1997. PMID: 9205124
Cortistatin is expressed in a distinct subset of cortical interneurons.
de Lecea L, del Rio JA, Criado JR, Alcántara S, Morales M, Danielson PE, Henriksen SJ, Soriano E, Sutcliffe JG. de Lecea L, et al. J Neurosci. 1997 Aug 1;17(15):5868-80. doi: 10.1523/JNEUROSCI.17-15-05868.1997. J Neurosci. 1997. PMID: 9221784 Free PMC article.
The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity.
de Lecea L, Kilduff TS, Peyron C, Gao X, Foye PE, Danielson PE, Fukuhara C, Battenberg EL, Gautvik VT, Bartlett FS 2nd, Frankel WN, van den Pol AN, Bloom FE, Gautvik KM, Sutcliffe JG. de Lecea L, et al. Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):322-7. doi: 10.1073/pnas.95.1.322. Proc Natl Acad Sci U S A. 1998. PMID: 9419374 Free PMC article.
Endogenous protein kinase A inhibitor (PKIalpha) modulates synaptic activity.
de Lecea L, Criado JR, Rivera S, Wen W, Soriano E, Henriksen SJ, Taylor SS, Gall CM, Sutcliffe JG. de Lecea L, et al. J Neurosci Res. 1998 Aug 1;53(3):269-78. doi: 10.1002/(SICI)1097-4547(19980801)53:3<269::AID-JNR1>3.0.CO;2-8. J Neurosci Res. 1998. PMID: 9698155
Neurons containing hypocretin (orexin) project to multiple neuronal systems.
Peyron C, Tighe DK, van den Pol AN, de Lecea L, Heller HC, Sutcliffe JG, Kilduff TS. Peyron C, et al. Among authors: de lecea l. J Neurosci. 1998 Dec 1;18(23):9996-10015. doi: 10.1523/JNEUROSCI.18-23-09996.1998. J Neurosci. 1998. PMID: 9822755 Free PMC article.
Structural and compositional determinants of cortistatin activity.
Criado JR, Li H, Jiang X, Spina M, Huitrón-Reséndiz S, Liapakis G, Calbet M, Siehler S, Henriksen SJ, Koob G, Hoyer D, Sutcliffe JG, Goodman M, de Lecea L. Criado JR, et al. Among authors: de lecea l. J Neurosci Res. 1999 Jun 15;56(6):611-9. doi: 10.1002/(SICI)1097-4547(19990615)56:6<611::AID-JNR7>3.0.CO;2-G. J Neurosci Res. 1999. PMID: 10374816
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