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Zero-order rectal delivery of theophylline in man with an osmotic system.
de Leede LG, de Boer AG, van Velzen SL, Breimer DD. de Leede LG, et al. J Pharmacokinet Biopharm. 1982 Oct;10(5):525-37. doi: 10.1007/BF01059035. J Pharmacokinet Biopharm. 1982. PMID: 7166736
Rectal drug administration: clinical pharmacokinetic considerations.
de Boer AG, Moolenaar F, de Leede LG, Breimer DD. de Boer AG, et al. Clin Pharmacokinet. 1982 Jul-Aug;7(4):285-311. doi: 10.2165/00003088-198207040-00002. Clin Pharmacokinet. 1982. PMID: 6126289 Review.
Rectal infusion of the model drug antipyrine with an osmotic delivery system.
de Leede LG, de Boer AG, Breimer DD. de Leede LG, et al. Biopharm Drug Dispos. 1981 Apr-Jun;2(2):131-6. doi: 10.1002/bdd.2510020205. Biopharm Drug Dispos. 1981. PMID: 7248477
Nifedipine kinetics and dynamics during rectal infusion to steady state with an osmotic system.
Kleinbloesem CH, van Harten J, de Leede LG, van Brummelen P, Breimer DD. Kleinbloesem CH, et al. Clin Pharmacol Ther. 1984 Sep;36(3):396-401. doi: 10.1038/clpt.1984.194. Clin Pharmacol Ther. 1984. PMID: 6467800 Clinical Trial.
Drug absorption by sublingual and rectal routes.
De Boer AG, De Leede LG, Breimer DD. De Boer AG, et al. Br J Anaesth. 1984 Jan;56(1):69-82. doi: 10.1093/bja/56.1.69. Br J Anaesth. 1984. PMID: 6140933 Review. No abstract available.
Pharmacokinetics of lidocaine and bupivacaine and stable isotope labelled analogues: a study in healthy volunteers.
Burm AG, de Boer AG, van Kleef JW, Vermeulen NP, de Leede LG, Spierdijk J, Breimer DD. Burm AG, et al. Biopharm Drug Dispos. 1988 Jan-Feb;9(1):85-95. doi: 10.1002/bod.2510090109. Biopharm Drug Dispos. 1988. PMID: 3342287 Clinical Trial.
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