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Three essential and conserved regions of the group II intron are proximal to the 5'-splice site.
de Lencastre A, Pyle AM. de Lencastre A, et al. RNA. 2008 Jan;14(1):11-24. doi: 10.1261/rna.774008. Epub 2007 Nov 26. RNA. 2008. PMID: 18039742 Free PMC article.
MicroRNAs both promote and antagonize longevity in C. elegans.
de Lencastre A, Pincus Z, Zhou K, Kato M, Lee SS, Slack FJ. de Lencastre A, et al. Curr Biol. 2010 Dec 21;20(24):2159-68. doi: 10.1016/j.cub.2010.11.015. Epub 2010 Dec 2. Curr Biol. 2010. PMID: 21129974 Free PMC article.
A microRNA feedback loop regulates global microRNA abundance during aging.
Inukai S, Pincus Z, de Lencastre A, Slack FJ. Inukai S, et al. Among authors: de lencastre a. RNA. 2018 Feb;24(2):159-172. doi: 10.1261/rna.062190.117. Epub 2017 Nov 7. RNA. 2018. PMID: 29114017 Free PMC article.
A single active-site region for a group II intron.
de Lencastre A, Hamill S, Pyle AM. de Lencastre A, et al. Nat Struct Mol Biol. 2005 Jul;12(7):626-7. doi: 10.1038/nsmb957. Epub 2005 Jun 26. Nat Struct Mol Biol. 2005. PMID: 15980867
A new protein folding screen: application to the ligand binding domains of a glutamate and kainate receptor and to lysozyme and carbonic anhydrase.
Armstrong N, de Lencastre A, Gouaux E. Armstrong N, et al. Among authors: de lencastre a. Protein Sci. 1999 Jul;8(7):1475-83. doi: 10.1110/ps.8.7.1475. Protein Sci. 1999. PMID: 10422836 Free PMC article.
A tertiary interaction that links active-site domains to the 5' splice site of a group II intron.
Boudvillain M, de Lencastre A, Pyle AM. Boudvillain M, et al. Among authors: de lencastre a. Nature. 2000 Jul 20;406(6793):315-8. doi: 10.1038/35018589. Nature. 2000. PMID: 10917534
Novel microRNAs differentially expressed during aging in the mouse brain.
Inukai S, de Lencastre A, Turner M, Slack F. Inukai S, et al. Among authors: de lencastre a. PLoS One. 2012;7(7):e40028. doi: 10.1371/journal.pone.0040028. Epub 2012 Jul 23. PLoS One. 2012. PMID: 22844398 Free PMC article.
Discovery of Novel microRNAs in Aging Caenorhabditis elegans.
de Lencastre A, Slack F. de Lencastre A, et al. Methods Mol Biol. 2015;1343:235-48. doi: 10.1007/978-1-4939-2963-4_18. Methods Mol Biol. 2015. PMID: 26420721
MicroRNAs mediate dietary-restriction-induced longevity through PHA-4/FOXA and SKN-1/Nrf transcription factors.
Smith-Vikos T, de Lencastre A, Inukai S, Shlomchik M, Holtrup B, Slack FJ. Smith-Vikos T, et al. Among authors: de lencastre a. Curr Biol. 2014 Oct 6;24(19):2238-46. doi: 10.1016/j.cub.2014.08.013. Epub 2014 Sep 18. Curr Biol. 2014. PMID: 25242029 Free PMC article.
Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development.
Kato M, de Lencastre A, Pincus Z, Slack FJ. Kato M, et al. Among authors: de lencastre a. Genome Biol. 2009;10(5):R54. doi: 10.1186/gb-2009-10-5-r54. Epub 2009 May 21. Genome Biol. 2009. PMID: 19460142 Free PMC article.
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